Inflammation News and Research

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Adopting healthy diet can help reverse risk of high triglycerides, despite genetic predisposition

Triglycerides, a type of fat in the blood, are important for good health. But having high triglycerides might increase a person's risk of heart disease, and may be a sign of metabolic syndrome--a combination of high blood pressure, high blood sugar, and too much fat accumulation at the waist.

25 Oct 2017

APC gene mutations play dual role in development of colorectal cancer, research suggests

Adenomatous polyposis coli (APC) is a gene whose mutations are associated with a rare, hereditary form of colorectal cancer known as familial adenomatous polyposis. Research led by scientists at the Institut Pasteur and Inserm have recently demonstrated that mutations to this gene do not only lead to the emergence of colon polyps; they also harm the immune system, leaving it unable to tackle inflammation of the colonic mucosa.

24 Oct 2017

Pollutant from forest and crop fires induces genetic damage in human lung cells

When exposed in a laboratory to pollution levels comparable to those found in the atmosphere of the Amazon region during the forest and crop burning season, human lung cells suffer severe DNA damage and stop dividing. After 72 hours of exposure, over 30% of the cultured cells are dead.

24 Oct 2017

Failure of doctors to recognize diabetes subtype puts patients’ health at risk

The health of people with diabetes is being put at risk due to the failure of doctors to recognize which type of diabetes they have, a new study in the journal Diabetes Care reports.

24 Oct 2017

Lung microbiome plays major role in asthma severity and response to treatment

While the microbiome has gained significant attention for its impact on digestive health in recent years, its effect on lung disease has largely remained unstudied.

24 Oct 2017

Study identifies protein that plays crucial role in diabetic retinopathy

For millions of Americans, their world is dissolving into an unrecognizable blur. Diabetic retinopathy is an eye disease affecting one-third of the estimated 30 million Americans who struggle with diabetes. As the patients' vision slowly fades, it never recovers and few treatments are available.

24 Oct 2017

People with depressive symptoms before disaster may experience increase in inflammation

People who exhibit even a few depressive symptoms before a major life stressor, such as a disaster, may experience an increase in inflammation -- a major risk factor for heart disease and other negative health conditions -- after the event, according to new research from Rice University.

23 Oct 2017

KU Leuven researchers identify new rapid response mechanism against bacterial infections

When bacteria enter our body, they kick-start a powerful immune response. But this chain of reactions doesn't fully account for our immediate responses. Researchers at KU Leuven, Belgium, show that so-called ion channels play a key role as 'first responders'.

23 Oct 2017

Researchers discover new regulatory role for protein that links diet and disease

A team of researchers from Case Western Reserve University School of Medicine have discovered how uncontrolled vitamin A metabolism in the gut can cause harmful inflammation.

23 Oct 2017

Study offers solution to protect against vaccine-enhanced respiratory disease

Researchers have discovered that a virus-like particle vaccine can prime the body's immune response and prevent the severe respiratory disease that results when patients given an early form of a vaccine for respiratory syncytial virus (RSV) are exposed to RSV, according to a study led by Georgia State University.

23 Oct 2017

RAND researchers estimate health care savings over next decade from biosimilars

Introducing "biosimilar" versions of complex biologic drugs used to treat illnesses such as cancer and rheumatoid arthritis could cut health care spending in the United States by $54 billion over the next decade, according to new analysis from the RAND Corporation.

23 Oct 2017

New study explores how herpes simplex virus may change during familial transmission

A new study explores how herpes simplex virus might change when passed from one individual to another, information that may prove useful in future development of therapeutics and vaccines.

20 Oct 2017

Daily aspirin therapy linked to reduced risk of HBV‐related liver cancer

A new study presented this week at The Liver Meeting – held by the American Association for the Study of Liver Diseases – found that daily aspirin therapy was significantly associated with a reduced risk in hepatitis B virus‐related liver cancer.

20 Oct 2017

Pharmacological stimulation of nicotinic receptor could be strategy to treat lung inflammation

It has been amply proven that smoking can cause serious diseases such as emphysema and cancer. A new study, however, shows that pharmacological stimulation of a specific type of nicotinic receptor in cells of the immune system could be a strategy to treat inflammatory lung disease.

20 Oct 2017

Better post-weaning diet can reverse potential consequences of early-life high-fat exposure

Research has shown that a mother's diet during pregnancy, particularly one that is high-fat, may program her baby for future risk of certain diseases such as diabetes. A new study from nutrition researchers at the University of Illinois shows that switching the offspring to a new diet--a low-fat diet, in this case--can reverse that programming.

20 Oct 2017

UCSD researchers discover how mutant gene amplifies inflammation to fuel cancer

A human gene called p53, which is commonly known as the "guardian of the genome," is widely known to combat the formation and progression of tumors. Yet, mutant forms of p53 have been linked to more cases of human cancer than any other gene.

19 Oct 2017

Rheumatoid arthritis may increase risk of developing COPD, research suggests

New research suggests that rheumatoid arthritis may increase the risk of developing chronic obstructive pulmonary disease (COPD).

19 Oct 2017

Study finds more patients with ulcerative colitis but less number of surgeries

Today, a higher number of patients with ulcerative colitis are able to keep their bowel and steer clear of surgery, as shown in a study from örebro University.

17 Oct 2017

Study reveals link between cancer relapse and body’s immune system

Results from a new study conducted at the Institute of Cancer Research, London, suggests cancer cells that remain in the body after treatment, utilize the immune system of the body to wake themselves up and boost their growth.

17 Oct 2017

Timing is crucial for corticosteroids to aid healing of tendons

A corticosteroid can improve the healing of damaged tendons, but it must be given at the right time, according to a new study from Linköping University in Sweden. In rats, the tendon became twice as strong. The results are presented in the journal Scientific Reports.

17 Oct 2017

Inflammation News and Research

Adopting healthy diet can help reverse risk of high triglycerides, despite genetic predisposition

APC gene mutations play dual role in development of colorectal cancer, research suggests

Pollutant from forest and crop fires induces genetic damage in human lung cells

Failure of doctors to recognize diabetes subtype puts patients’ health at risk

Lung microbiome plays major role in asthma severity and response to treatment

Study identifies protein that plays crucial role in diabetic retinopathy

People with depressive symptoms before disaster may experience increase in inflammation

KU Leuven researchers identify new rapid response mechanism against bacterial infections

Researchers discover new regulatory role for protein that links diet and disease

Study offers solution to protect against vaccine-enhanced respiratory disease

RAND researchers estimate health care savings over next decade from biosimilars

New study explores how herpes simplex virus may change during familial transmission

Daily aspirin therapy linked to reduced risk of HBV‐related liver cancer

Pharmacological stimulation of nicotinic receptor could be strategy to treat lung inflammation

Better post-weaning diet can reverse potential consequences of early-life high-fat exposure

UCSD researchers discover how mutant gene amplifies inflammation to fuel cancer

Rheumatoid arthritis may increase risk of developing COPD, research suggests

Study finds more patients with ulcerative colitis but less number of surgeries

Study reveals link between cancer relapse and body’s immune system

Timing is crucial for corticosteroids to aid healing of tendons

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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