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New insights into how endoplasmic reticulum and lysosomes coordinate protein production

Janelia researchers have uncovered a novel way that two of the structures inside cells-the endoplasmic reticulum (ER) and lysosomes-coordinate the production of proteins, highlighting how interactions between organelles are important for regulating cellular processes.

11 Nov 2025

AI repurposes routine CT scans to detect hidden bone loss

Computed tomography (CT) scans of the chest, abdomen, and spine, taken originally to detect problems such as kidney stones or growths on the lungs, can be repurposed through artificial intelligence (AI) to catch signs of bone loss, a new study shows.

11 Nov 2025

Amyloid-clearing drug fails to change waste clearance function in the brains of Alzheimer's patients

A group from Osaka Metropolitan University in Japan, led by graduate student Tatsushi Oura and Dr. Hiroyuki Tatekawa, found that treatment using the drug lecanemab to remove amyloid plaques in the brain does not change the waste clearance function in the brains of Alzheimer's disease (AD) patients in the short term.

11 Nov 2025

Midlife blood test may reveal Alzheimer’s disease risk in advance

A simple blood test for platelet activity at middle age could one day help identify people at risk for Alzheimer's disease decades ahead of time, allowing for possible preventive therapy.

11 Nov 2025

Nanoparticle vaccine eliminates HPV-induced tumors in animal model

A nanoparticle vaccine designed to fight cancers induced by human papillomavirus (HPV) eradicated tumors in an animal model of late-stage metastatic disease, UT Southwestern Medical Center scientists report in a new study published in the Proceedings of the National Academy of Sciences (PNAS).

11 Nov 2025

Anticoagulants increase bleeding post-ablation with no added stroke benefit

A minimally invasive heart procedure to correct irregular heart rhythms called catheter ablation may reduce the risk of stroke enough that some patients can discontinue blood thinners, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

11 Nov 2025

One-month dual therapy strategy offers advantages for AFib patients and clinicians

New research found a simplified clot-preventing medication regimen following stent placement in adults with atrial fibrillation was just as safe and effective in preventing strokes, heart attack and death, when compared to a standard year-long treatment regimen, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

11 Nov 2025

St. Jude study maps treatment strategy for rare infant gliomas

Clinician-scientists at St. Jude Children's Research Hospital and collaborators have conducted the largest study of infant-type hemispheric glioma (IHG) ever reported, uncovering key factors that could be used to guide treatment strategies for this rare pediatric brain tumor.

11 Nov 2025

Researchers achieve long-term remission with novel T cell therapies for HPV-related cancers

Researchers from Rutgers Cancer Institute, New Jersey's only National Cancer Institute (NCI) - designated Comprehensive Cancer Center, and RWJBarnabas Health, along with colleagues from the National Cancer Institute, a center of the National Institutes of Health, announced findings from two HPV-related studies that highlight the potential of novel T cell therapies to achieve long-lasting remission and complete tumor regression in patients with advanced epithelial cancers.

10 Nov 2025

Single daily polypill improves heart function and quality of life in heart failure patients

Adults with heart failure with reduced ejection fraction (HFrEF) who took a "polypill" combining medications prescribed for the treatment of heart failure, had improved heart function and symptoms, better quality of life, fewer hospitalizations and greater medication adherence than those taking the medications individually, according to a late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

MRI-based blood flow testing offers better answers for unexplained chest pain

Chest pain may still be angina even when coronary angiogram testing shows the main heart arteries look clear. Using stress cardiac stress MRI testing to measure blood flow around the heart appears to improve diagnosis and patient quality of life.

10 Nov 2025

Study finds reduced cortical choline levels in people with anxiety disorders

People with anxiety disorders have lower levels of choline in their brains, according to research from UC Davis Health.

10 Nov 2025

As health companies get bigger, so do the bills. It’s unclear if Trump’s team will intervene.

A cancer patient might live in a town with four oncology groups, but only one accepts his insurance — the one owned by his insurer.

10 Nov 2025

OSU researchers design a highly effective, low-dose, manganese-MOF MRI agent

Scientists at Oregon State University have filed a patent on a design for a new magnetic resonance imaging contrast agent with the potential to outperform current agents while being less toxic to patients and more environmentally friendly.

7 Nov 2025

New radioimmunotherapy approach shows potential to cure HER2-positive breast cancer

A new radioimmunotherapy approach has the potential to cure human epidermal growth factor receptor 2 (HER2)-positive breast cancer, according to new research published in the November issue of The Journal of Nuclear Medicine.

7 Nov 2025

Harnessing nanotechnology to deliver CBD to the brain for neuropathic pain relief

Reaching for CBD-infused lotion or oil may seem like a low-risk way to find pain relief, but little is actually known about the impact that CBD has on the nervous system.

7 Nov 2025

Mapping the brain's body regulation and sensing system using 7 Tesla MRI

Jiahe Zhang, PhD, of the Department of Psychiatry at Mass General Brigham, is the lead author of the paper published in Nature Neuroscience, "Cortical and subcortical mapping of the human allostatic-interoceptive system using 7 Tesla fMRI."

7 Nov 2025

Comprehensive kinase atlas reveals new insights into cell signaling and disease

The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme's "tail" called phosphorylation patterns.

7 Nov 2025

New initiative focuses on advancing human disease research through AI and frontier biology

Mark Zuckerberg and Priscilla Chan today announced the launch of a first-of-its-kind initiative combining frontier artificial intelligence and frontier biology to dramatically accelerate scientific progress toward understanding and addressing human disease.

7 Nov 2025

Researchers identify a previously unknown cellular mechanism crucial to coronavirus replication

The discovery could serve as a starting point for antiviral strategies. A research team at Ruhr University Bochum, Germany, has identified a previously unknown cellular mechanism crucial to the replication of coronaviruses: c-Jun N-terminal kinase (JNK) is activated during infection with human coronavirus HCoV-229E and mediates the phosphorylation of the viral nucleocapsid (N) protein, an integral step in the virus cycle.

7 Nov 2025

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Imaging News and Research

New insights into how endoplasmic reticulum and lysosomes coordinate protein production

AI repurposes routine CT scans to detect hidden bone loss

Amyloid-clearing drug fails to change waste clearance function in the brains of Alzheimer's patients

Midlife blood test may reveal Alzheimer’s disease risk in advance

Nanoparticle vaccine eliminates HPV-induced tumors in animal model

Anticoagulants increase bleeding post-ablation with no added stroke benefit

One-month dual therapy strategy offers advantages for AFib patients and clinicians

St. Jude study maps treatment strategy for rare infant gliomas

Researchers achieve long-term remission with novel T cell therapies for HPV-related cancers

Single daily polypill improves heart function and quality of life in heart failure patients

MRI-based blood flow testing offers better answers for unexplained chest pain

Study finds reduced cortical choline levels in people with anxiety disorders

As health companies get bigger, so do the bills. It’s unclear if Trump’s team will intervene.

OSU researchers design a highly effective, low-dose, manganese-MOF MRI agent

New radioimmunotherapy approach shows potential to cure HER2-positive breast cancer

Harnessing nanotechnology to deliver CBD to the brain for neuropathic pain relief

Mapping the brain's body regulation and sensing system using 7 Tesla MRI

Comprehensive kinase atlas reveals new insights into cell signaling and disease

New initiative focuses on advancing human disease research through AI and frontier biology

Researchers identify a previously unknown cellular mechanism crucial to coronavirus replication

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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