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DAPK1 protein may be a promising new therapeutic target for most aggressive breast cancers

Although traditionally understood to induce death in cancer cells, researchers at The University of Texas MD Anderson Cancer Center have discovered that the DAPK1 protein is actually essential for growth in breast and other cancers with mutations in the TP53 gene. This discovery indicates DAPK1 may be a promising new therapeutic target for many of the most aggressive cancers.

16 Jun 2015

Vitamin D deficiency can leave people less able to fight HIV-1 infection

Vitamin D plays an important part in the human immune response and deficiency can leave individuals less able to fight infections like HIV-1. Now an international team of researchers has found that high-dose vitamin D supplementation can reverse the deficiency and also improve immune response.

16 Jun 2015

Study highlights discovery of genetic variants linked to mucinous ovarian carcinomas

New research by an international team including Keck Medicine of USC scientists is bringing the origins of ovarian cancer into sharper focus.

16 Jun 2015

Mayo Clinic, United Therapeutics partner to build and operate new lung restoration center on Mayo campus

Mayo Clinic in Jacksonville, Fla., and United Therapeutics Corporation today announced a collaboration to build and operate a lung restoration center on the Mayo campus. The goal is to significantly increase the volume of lungs for transplantation by preserving and restoring selected marginal donor lungs, making them viable for transplantation. The restored lungs will be made available to patients at Mayo Clinic and other transplant centers throughout the United States.

16 Jun 2015

Stress and worry of premature birth does not affect mother's parenting behaviour

The stress and worry of giving birth prematurely does not adversely affect a mother's parenting behaviour, according to researchers at the University of Warwick.

16 Jun 2015

Researchers uncover new mechanism that innate immune system uses to curb viral infections

An innovative mechanism that the innate immune system uses to control viral infections has been uncovered by researchers at the University Medical Centers in Mainz and Freiburg. Central to this is the discovery that two different but related elements of the immune system can act together in concert to fight, for example, rotavirus infections.

16 Jun 2015

Scientists report that mouse with weak bones appears to have strong metabolism

One mouse with weak bones appears to have a strong metabolism, even on a high-fat diet, scientists report. While weaker bones are clearly not a good thing, scientists suspect that, somewhere in the conversation between the genetically engineered mouse's skeleton and the rest of its body, there may be an answer that helps obese individuals avoid some of the worst ravages of this health epidemic.

16 Jun 2015

Helmholtz Zentrum München scientists identify how Epstein-Barr virus conceals in human cells

Scientists at Helmholtz Zentrum München have now discovered how Epstein-Barr virus (EBV) conceals itself in human cells. A main culprit for its bad visibility by the immune system is the viral protein LMP2A. As published in the scientific journal PLOS Pathogens, the protein helps EBV-infected cells hide from T cells. This camouflage through the LMP2A protein may play a major role in the causation of cancer by EBV.

16 Jun 2015

New evidence suggests that biodiversity limits disease outbreaks among humans, wildlife

With infectious diseases increasing worldwide, the need to understand how and why disease outbreaks occur is becoming increasingly important. Looking for answers, a team of University of South Florida biologists and colleagues found broad evidence that supports the controversial 'dilution effect hypothesis,' which suggests that biodiversity limits outbreaks of disease among humans and wildlife.

16 Jun 2015

Orange sweet potato reduces prevalence and duration of diarrhea in children

A new study has found that orange sweet potato (OSP) reduced both the prevalence and duration of diarrhea in young children in Mozambique.

16 Jun 2015

Scientists develop new technique to analyze bacterial populations

Scientists from the Icahn School of Medicine at Mount Sinai have developed a new technique to more precisely analyze bacterial populations, to reveal epigenetic mechanisms that can drive virulence. The new methods hold the promise of a potent new tool to offset the growing challenge of antibiotic resistance by bacterial pathogens.

16 Jun 2015

Researchers find lymphatic vessels in the central nervous system

In a study published in The Journal of Experimental Medicine, researchers working at the Wihuri Research Institute and the University of Helsinki report a surprising finding that challenges current anatomy and histology textbook knowledge: Lymphatic vessels are found in the central nervous system where they were not known to exist.

16 Jun 2015

Innovative programme reduces teachers’ violence in Ugandan primary schools

An innovative programme of activities used in Ugandan primary schools has succeeded in reducing violence by teachers against children by 42%, according to new research published in The Lancet Global Health. The study is published on 16 June, the Day of the African Child.

15 Jun 2015

SynGenXTM-1000 System adopted by Anthony Nolan Cell Therapy Centre

SynGen Inc., a company that focuses on the development and commercialization of instrument systems that harvest stem and progenitor cells from umbilical cord blood, bone marrow, peripheral blood, and cell culture, announced today that, after extensive review of competitive systems, The Anthony Nolan Cell Therapy Centre in Nottingham UK has chosen the SynGenXTM-1000 System and the CryoPRO Workstation to process its umbilical cord blood units. Anthony Nolan has signed a 5-year contract with Deva Medical Electronics Ltd, SynGen Inc.’s UK distributor, for the supply of SynGen’s products and all post-sales support, starting late summer 2015.

15 Jun 2015

BioLight expands relationship with Ora to develop TeaRx multi-parameter diagnostic test for DES

BioLight Life Sciences Investments, a firm that invests in, manages and commercializes biomedical innovations in ophthalmology and cancer diagnostics, today announced that it has expanded its relationship with Ora, Inc., a world-leading independent, full-service ophthalmic contract research organization and product development firm, via the signing of a Collaboration Agreement (the "Agreement") pursuant to which the companies will work together to advance the clinical, regulatory and commercial development of BioLight's TeaRx multi-parameter diagnostic test for dry eye syndrome ("DES").

15 Jun 2015

OmniVision introduces CameraChip sensor for medical and industrial applications

OmniVision Technologies, Inc., a leading developer of advanced digital imaging solutions, today announced a new ultra-compact CameraChip sensor for medical and industrial applications.

15 Jun 2015

Laurent reports positive topline results from LAU-7b Phase 1b trial in adult CF patients

Laurent Pharmaceuticals Inc. announced today positive topline results from a Phase 1b clinical trial with LAU-7b in adult CF patients. LAU-7b is a novel oral formulation of fenretinide, a synthetic retinoid investigated for its lipid modulating properties and potential to address the aberrant inflammatory response in CF.

15 Jun 2015

Scientists find way to accelerate wound healing in diabetic mice

One of the body's own tools for preventing wound infections may actually interfere with wound healing, according to new research from Boston Children's Hospital. In a study published online in Nature Medicine, scientists from the hospital's Program in Cellular and Molecular Medicine found they could speed up wound healing in diabetic mice by keeping immune cells called neutrophils from producing bacteria-trapping neutrophil extracellular traps (NETs).

15 Jun 2015

Supporting Innovation in Life Sciences

In this interview, News-Medical speaks to Ger Brophy about the importance of supporting technological innovation in the life sciences.

15 Jun 2015

DATATRAK International introduces next generation clinical trial management system

DATATRAK International, Inc., the leader in developing cloud-based, unified dClinical® technologies and delivering related services for the clinical trials industry, today introduced the next generation clinical trial management system, UX CTMS 360.

15 Jun 2015

Research News and Research

DAPK1 protein may be a promising new therapeutic target for most aggressive breast cancers

Vitamin D deficiency can leave people less able to fight HIV-1 infection

Study highlights discovery of genetic variants linked to mucinous ovarian carcinomas

Mayo Clinic, United Therapeutics partner to build and operate new lung restoration center on Mayo campus

Stress and worry of premature birth does not affect mother's parenting behaviour

Researchers uncover new mechanism that innate immune system uses to curb viral infections

Scientists report that mouse with weak bones appears to have strong metabolism

Helmholtz Zentrum München scientists identify how Epstein-Barr virus conceals in human cells

New evidence suggests that biodiversity limits disease outbreaks among humans, wildlife

Orange sweet potato reduces prevalence and duration of diarrhea in children

Scientists develop new technique to analyze bacterial populations

Researchers find lymphatic vessels in the central nervous system

Innovative programme reduces teachers’ violence in Ugandan primary schools

SynGenXTM-1000 System adopted by Anthony Nolan Cell Therapy Centre

BioLight expands relationship with Ora to develop TeaRx multi-parameter diagnostic test for DES

OmniVision introduces CameraChip sensor for medical and industrial applications

Laurent reports positive topline results from LAU-7b Phase 1b trial in adult CF patients

Scientists find way to accelerate wound healing in diabetic mice

Supporting Innovation in Life Sciences

DATATRAK International introduces next generation clinical trial management system

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