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Children are active transmitters of COVID-19, shows study

A team of investigators from CDDEP, the Government of Tamil Nadu, and Andhra Pradesh studied disease transmission patterns in 575,071 individuals exposed to 84,965 confirmed cases of COVID-19.

1 Oct 2020

Long-term care system in British Columbia minimizes SARS-CoV-2 transmission

British Columbia found that BC was better prepared for the pandemic and responded in a more coordinated and decisive manner, leading to far fewer deaths than in Ontario.

1 Oct 2020

23 SARS-CoV-2 strains circulating in the Philippines

In a new study published on the medRxiv* preprint server, scientists reported coding of complete genome sequences of 23 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains in the Philippines.

1 Oct 2020

Children and young adults have greater potential to transmit SARS-CoV-2 virus

A study of more than a half-million people in India who were exposed to the novel coronavirus SARS-CoV-2, or COVID-19, suggests that the virus' continued spread is driven by only a small percentage of those who become infected.

1 Oct 2020

Lung tissue in fatal COVID-19 shows broad cell tropism and extensive damage

In a recent preprint paper published on the medRxiv server, researchers demonstrated their investigation of fatal COVID-19 patients to assess infection in various cell types and the extent of damage it caused to the lung tissues.

30 Sep 2020

Genetic heritage from Neanderthals linked to severe COVID-19

Since first appearing in late 2019, the novel virus, SARS-CoV-2, has had a range of impacts on those it infects. Some people become severely ill with COVID-19, the disease caused by the virus, and require hospitalization, whereas others have mild symptoms or are even asymptomatic.

30 Sep 2020

Tufts University to lead $100 million program to address threats posed by zoonotic viral diseases

Tufts University will lead a $100 million, five-year program to understand and address threats posed by zoonotic viral diseases that can "spill over" from animals to humans, such as SARS-CoV-2, in an effort to reduce risk of infection, amplification, and spread, the United States Agency for International Development announced today.

30 Sep 2020

Investigational mRNA vaccine to prevent SARS-CoV-2 shows promise in older adults

A Phase 1 trial of an investigational mRNA vaccine to prevent SARS-CoV-2 infection has shown that the vaccine is well-tolerated and generates a strong immune response in older adults.

30 Sep 2020

Researchers identify the target structures for T-cell response against SARS-CoV-2

Our immune system can efficiently fend off viral diseases. Two types of immune cells play an important role in this process: The T-cells, which firstly can directly destroy virus-infected cells and secondly enable the formation of efficient, virus-neutralizing antibodies by B-cells.

30 Sep 2020

Maternal immune cells could bring SARS-CoV-2 to the placenta

Researchers from Canada and Brazil collaborated to explore the possibility of perinatal transmission of the virus from pregnant mothers to their babies and the risk of preterm birth.

30 Sep 2020

Discovery of high affinity binders for SARS-CoV-2 spike protein

An exciting, 'tour-de-force' paper by researchers from the Massachusetts Institute of Technology describes de novo discovery of high-affinity peptide binders for SARS-CoV-2 spike glycoprotein, which opens the door for the development of rapid viral identification or conjugates for virus-directed delivery of therapeutics.

30 Sep 2020

SARS-CoV-2 D614G variant enhances infectivity, replication and transmission

Researchers in the United States and Japan have conducted a study showing a common mutation in the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) - the agent that causes coronavirus disease 2019 (COVD-19) - enhances the infectivity, replication, and early transmission of the virus.

30 Sep 2020

Researchers create drug-like compounds to destroy coronavirus' frameshifting element

Scripps Research chemist Matthew Disney, PhD, and colleagues have created drug-like compounds that, in human cell studies, bind and destroy the pandemic coronavirus' so-called "frameshifting element" to stop the virus from replicating.

30 Sep 2020

Neanderthal gene variant linked to higher risk of developing severe COVID-19

A study published in Nature shows that a segment of DNA that causes their carriers to have an up to three times higher risk of developing severe COVID-19 is inherited from Neandertals. The study was conducted by researchers at Karolinska Institutet and Max Planck Institute for Evolutionary Anthropology.

30 Sep 2020

Danish vs. Swedish data shows social interaction major risk factor for SARS-CoV-2 infection

A new study published on the preprint server medRxiv* in September 2020 compares the prevalence of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Danish and Swedish healthcare workers, to conclude that “social interaction is one of the biggest risk factors for getting infected with SARS-CoV-2.”

30 Sep 2020

Study shows how human cells fight viral infections with the emergence of SARS-CoV-2

Science's pursuits of unraveling how human cells fight viral infections kicked into high gear in 2020 with the devastating emergence of the SARS-CoV-2 virus.

30 Sep 2020

A TLR2 agonist reduces SARS-CoV-2 in upper respiratory tract of ferret model

In a recent bioRxiv* preprint paper, Professor Miles W. Carroll et al. study an agonist for reducing the SARS-CoV-2's viral load. They show that prophylactic intra-nasal administration of TLR2/6 (toll-like receptor) agonist, INNA-051, reduces viral RNA in the nose and throat, in a ferret model.

30 Sep 2020

Different triggers for Kawasaki disease suggest slightly different genetic susceptibilities

Researchers at University of California San Diego report that while Kawasaki disease (KD) occurs in clusters, the traits, and thus the triggers of the inflammatory disease vary among clusters. The findings are published in the September 2020 online issue of The Journal of Pediatrics.

30 Sep 2020

Researchers develop research model to understand the impact of coronavirus on lungs

Scientists at Boston University's National Emerging Infectious Diseases Laboratories (NEIDL) and the Center for Regenerative Medicine (CReM) joined forces to develop the most relevant research model possible for understanding how the coronavirus virus impacts the lungs, by engineering living, "breathing" human lung cells from stem cells for the task.

30 Sep 2020

Abacus Diagnostica's new multiplex assay provides reliable influenza, COVID-19 diagnosis in 75 minutes

Abacus Diagnostica is a small Finnish company developing and manufacturing assays and devices for rapid molecular diagnostics. Since the beginning of COVID-19 outbreak the company has worked decisively on the development of SARS-CoV-2 diagnostics.

30 Sep 2020

SARS News and Research

Children are active transmitters of COVID-19, shows study

Long-term care system in British Columbia minimizes SARS-CoV-2 transmission

23 SARS-CoV-2 strains circulating in the Philippines

Children and young adults have greater potential to transmit SARS-CoV-2 virus

Lung tissue in fatal COVID-19 shows broad cell tropism and extensive damage

Genetic heritage from Neanderthals linked to severe COVID-19

Tufts University to lead $100 million program to address threats posed by zoonotic viral diseases

Investigational mRNA vaccine to prevent SARS-CoV-2 shows promise in older adults

Researchers identify the target structures for T-cell response against SARS-CoV-2

Maternal immune cells could bring SARS-CoV-2 to the placenta

Discovery of high affinity binders for SARS-CoV-2 spike protein

SARS-CoV-2 D614G variant enhances infectivity, replication and transmission

Researchers create drug-like compounds to destroy coronavirus' frameshifting element

Neanderthal gene variant linked to higher risk of developing severe COVID-19

Danish vs. Swedish data shows social interaction major risk factor for SARS-CoV-2 infection

Study shows how human cells fight viral infections with the emergence of SARS-CoV-2

A TLR2 agonist reduces SARS-CoV-2 in upper respiratory tract of ferret model

Different triggers for Kawasaki disease suggest slightly different genetic susceptibilities

Researchers develop research model to understand the impact of coronavirus on lungs

Abacus Diagnostica's new multiplex assay provides reliable influenza, COVID-19 diagnosis in 75 minutes

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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