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Mistakes in mismatch repair genes may accurately predict response to certain immunotherapy drugs

In a report of a proof-of-principle study of patients with colon and other cancers for whom standard therapies failed, researchers at the Johns Hopkins Kimmel Cancer Center say that mistakes in so-called mismatch repair genes, first identified by Johns Hopkins and other scientists two decades ago, may accurately predict who will respond to certain immunotherapy drugs known as PD-1 inhibitors. Such drugs aim to disarm systems developed by cancer cells to evade detection and destruction by immune system cells.

30 May 2015

PEPRR intervention successfully reduces stress of cancer caregivers

Stem cell transplant is essential in the care of many blood cancers, but leaves patients requiring in-home care for months after.

30 May 2015

KeyGenes platform could be useful for testing quality of stem cell transplants

A snapshot of gene activity is now all that's necessary to determine what organ or tissue type that a cluster of fetal stem cells will ultimately become. An algorithm developed by a team of Dutch scientists makes it possible to match what's happening inside of an immature stem cell to known human fetal cell gene expression, thus identifying what the stem cell has the potential to be.

30 May 2015

RPCI-led research team to share clinical results of entolimod drug at ASCO 2015

A collaborative team of researchers led by Alex A. Adjei, MD, PhD, FACP, of Roswell Park Cancer Institute (RPCI) will share results from the first clinical study of the anticancer effects of the novel agent entolimod at the American Society of Clinical Oncology (ASCO) 51st Annual Meeting in Chicago.

30 May 2015

Novel biosensor chip measures pH, temperature, drugs and metabolism-related molecules

The future of medicine lies in ever greater precision, not only when it comes to diagnosis but also drug dosage. The blood work that medical staff rely on is generally a snapshot indicative of the moment the blood is drawn before it undergoes hours - or even days - of analysis.

30 May 2015

2015 EuroHeartCare annual meeting to highlight recent advances in cardiovascular nursing research, practice

The cardiovascular nursing event of the year is heading south to Croatia. EuroHeartCare is the official annual meeting of the Council on Cardiovascular Nursing and Allied Professions (CCNAP) of the European Society of Cardiology (ESC).

30 May 2015

Penn researchers to present clinical data at 2015 ASCO Annual Meeting

Researchers from the Abramson Cancer Center of the University of Pennsylvania and Penn's Perelman School of Medicine will present results from several clinical trials and other key studies during the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting from May 29 through June 2.

30 May 2015

Researchers discover new source for cells that can develop into coronary vessels

The heart has its own dedicated blood supply, with coronary arteries that supply oxygen-rich blood to the heart and cardiac veins that remove deoxygenated blood. This system of vessels nourishes the heart, enabling it to pump blood to all the other organs and tissues of the body. Yet despite their critical importance, the process and molecules required for coronary vessel development have not been fully determined.

30 May 2015

Fragrance chemical linalyl acetate could cause allergic eczema

Linalyl acetate, a fragrance chemical that is one of the main constituents of the essential oil of lavender, is not on the list of allergenic compounds pursuant to the EU Cosmetics Directive. Thus, it does not need to be declared on cosmetic products sold within the EU. Recent studies at the University of Gothenburg have shown that linalyl acetate can cause allergic eczema.

30 May 2015

Researchers uncover critical role for two proteins in chromatin structure

A team of researchers at the IRCM led by François Robert, PhD, uncovered a critical role for two proteins in chromatin structure. Their breakthrough, recently published in the scientific journal Molecular Cell, helps explain how DNA is organized in our cells. This discovery could lead to a better understanding of what causes certain types of cancer, such as lymphoma.

30 May 2015

B Floral raises awareness for Ovarian Cancer Research Fund

From Los Angeles to the Hamptons, New York's premiere floral event design company, B Floral, is giving back and helping raise awareness for Ovarian Cancer Research Fund (OCRF).

30 May 2015

Researchers awarded $3.86 million NIH grant to tackle the issue of 'mosaicism' in schizophrenia

Why does schizophrenia happen, and how can we improve treatment for it? These basic questions persist despite years of research on one of the most puzzling, and debilitating, mental illnesses. Now, a University of Michigan Medical School team and their colleagues will take a new approach to addressing these questions by searching for genetic clues in postmortem brain tissues of people with and without schizophrenia.

30 May 2015

Study suggests race-specific equations to aid clinicians better calculate warfarin dosage

A new report demonstrates that clinical and genetic factors affecting dose requirements for warfarin vary by race. The study, published online today in Blood, the Journal of the American Society of Hematology, proposes race-specific equations to help clinicians better calculate warfarin dosage.

30 May 2015

Brain Tumor Biotech Summit held in Manhattan on 29 May, 2015

Voices Against Brain Cancer, a national non-profit organization committed to finding a cure for brain cancer and brain tumors, and the Feinstein Institute for Medical Research in Long Island, will be hosting a Brain Tumor Biotech Summit on Friday, May 29th, 2015 at Lenox Hill Hospital's Einhorn Auditorium in Manhattan.

30 May 2015

Modified herpes virus improves survival in melanoma patients

University of Louisville researcher Jason Chesney, M.D., Ph.D., deputy director of the James Graham Brown Cancer Center, and a team of international scientists found that stage IIIb to IV melanoma patients treated with a modified cold sore (herpes) virus had improved survival.

30 May 2015

Racial socialization in early childhood may increase child's ability to excel in school

A child's ability to succeed academically is one of the strongest determinants of his or her future quality of life. In particular, it has been directly linked to overall longevity and several other critical health outcomes.

30 May 2015

MD Anderson Cancer Center's Jim Allison to receive Science of Oncology Award at ASCO 2015

The world's leading organization of oncologists will honor Jim Allison, Ph.D., for his pioneering research that led to a new way to treat cancer by unleashing an immune system attack rather than targeting tumors directly.

30 May 2015

Migraine surgery found effective among adolescent patients

As in adults, migraine surgery is effective for selected adolescent patients with severe migraine headaches that don't respond to standard treatments, reports a study in the June issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

30 May 2015

FVCG portfolio companies selected to present research at Bio International 2015

Actinobac Biomed, NovoPedics, Inc. and MentiNova, Inc., three biotech start-up companies originally funded with investments from Foundation Venture Capital Group (FVCG), have been selected to present their research at Bio International 2015 as part of the Start-Up Stadium and Company Presentation forums offered at the Conference, announced FVCG President James M. Golubieski.

30 May 2015

Doctor Evidence to contribute valuable clinical data to IBM Watson's oncology solutions, developer ecosystem

Today, Doctor Evidence, a clinical health research data provider, announced a content partnership with IBM Watson to contribute valuable clinical cancer research content to Watson's oncology solutions and developer ecosystem.

30 May 2015

Research News and Research

Mistakes in mismatch repair genes may accurately predict response to certain immunotherapy drugs

PEPRR intervention successfully reduces stress of cancer caregivers

KeyGenes platform could be useful for testing quality of stem cell transplants

RPCI-led research team to share clinical results of entolimod drug at ASCO 2015

Novel biosensor chip measures pH, temperature, drugs and metabolism-related molecules

2015 EuroHeartCare annual meeting to highlight recent advances in cardiovascular nursing research, practice

Penn researchers to present clinical data at 2015 ASCO Annual Meeting

Researchers discover new source for cells that can develop into coronary vessels

Fragrance chemical linalyl acetate could cause allergic eczema

Researchers uncover critical role for two proteins in chromatin structure

B Floral raises awareness for Ovarian Cancer Research Fund

Researchers awarded $3.86 million NIH grant to tackle the issue of 'mosaicism' in schizophrenia

Study suggests race-specific equations to aid clinicians better calculate warfarin dosage

Brain Tumor Biotech Summit held in Manhattan on 29 May, 2015

Modified herpes virus improves survival in melanoma patients

Racial socialization in early childhood may increase child's ability to excel in school

MD Anderson Cancer Center's Jim Allison to receive Science of Oncology Award at ASCO 2015

Migraine surgery found effective among adolescent patients

FVCG portfolio companies selected to present research at Bio International 2015

Doctor Evidence to contribute valuable clinical data to IBM Watson's oncology solutions, developer ecosystem

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