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Amgen creates catalog of qualified tools and reagents to advance basic discoveries in biology

Amgen today announced the creation of a catalog of qualified tools and reagents available to academic institutions to help further research and advance basic discoveries in biology, as well as deepen relationships with academic institutions.

29 May 2015

Study highlights recent trends in non-fatal suicidal events in the U.S. Army

Although the U.S. Army suicide rate is known to have risen sharply over the past decade, information about medically documented, non-fatal suicidal behaviors is far more limited. According to findings published in Psychiatry: Interpersonal & Biological Processes incidence rates of suicide ideation and suicide attempts increased annually among Soldiers during the years 2004-2009.

29 May 2015

DNA analysis reveals how ovarian cancer takes genetic twists and turns to outsmart chemotherapy

The largest complete DNA analysis of ovarian cancer in the world, published overnight in Nature, has revealed unprecedented new insight into the genetic twists and turns a deadly form of the disease takes to outsmart chemotherapy, potentially changing treatment approaches for women around the world.

29 May 2015

Incidence of melanoma on the rise among children and young adults

The incidence of melanoma, a deadly form of skin cancer, has increased by more than 250% among children, adolescents and young adults since 1973, according to award-winning research to be presented by Roswell Park Cancer Institute (RPCI) at the American Society of Clinical Oncology (ASCO) 51st Annual Meeting in Chicago.

29 May 2015

Poor sleep significantly decreases cognitive performance in autistic and neurotypical children

One night of poor sleep significantly decreases performance on intelligence tests in children with autism spectrum disorder (ASD) and also in neurotypical children (without ASD). This is the conclusion made by researchers at the Hôpital Rivière-des-Prairies, affiliated with the Institut universitaire en santé mentale de Montréal and Université de Montréal.

29 May 2015

Study reveals new molecular mechanism that helps protect genome from harmful effect of UV radiations

Researchers have uncovered a new molecular mechanism whereby human cells protect their genome from the detrimental effect of UV radiation and govern DNA replication in cellular mitosis, which, when it malfunctions, leads to harmful results.

29 May 2015

Strategy-based cognitive training improves cognitive, psychological health after traumatic brain injury

In the first study of its kind, veterans and civilians with traumatic brain injury showed improved cognitive performance and psychological and neural health following strategy-based cognitive training. The Department of Defense-funded study, published this week in Neuropsychological Rehabilitation, was conducted by an interdisciplinary team of cognitive neuroscientists, rehabilitation specialists, and neuroimaging experts from the Center for BrainHealth at The University of Texas at Dallas.

29 May 2015

UCLA researchers successfully measure liver function in potential organ donors using finger-probe device

A portable, finger-probe device successfully measured liver function in brain dead adult organ donors, a finding that could change the way organs are assessed and save thousands of dollars per transplant, a UCLA study has found.

29 May 2015

Monoclonal antibody nivolumab improves survival rates of melanoma patients

The monoclonal antibody nivolumab has shown promise as a therapeutic agent, particularly by improving the survival rates of melanoma patients. Jeffrey S. Weber, M.D., Ph.D., director of the Donald A. Adam Comprehensive Melanoma Research Center at Moffitt Cancer Center will be presenting data from a retrospective analysis of the safety of nivolumab in 4 ongoing phase I-III studies in melanoma patients at the 2015 American Society of Clinical Oncology Annual Meeting in Chicago.

29 May 2015

MIT researchers find neural circuit that appears to cause decision-making in approach-avoidance conflict

Some decisions arouse far more anxiety than others. Among the most anxiety-provoking are those that involve options with both positive and negative elements, such choosing to take a higher-paying job in a city far from family and friends, versus choosing to stay put with less pay.

29 May 2015

MEDI4736 and tremelimumab combination shows acceptable safety, potential efficacy in NSCLC patients

Advanced non-small cell lung cancer (NSCLC) patients have few effective treatment options and low 5-year survival rates. The checkpoint inhibitors MEDI4736 and tremelimumab have both demonstrated acceptable safety and potential efficacy when used as single-agents in several different types of cancer.

29 May 2015

JAK2 inhibitor ruxolitinib shows promise in treating CMML patients

Chronic myelomonocytic leukemia (CMML) is a rare type of myelodysplastic, myeloproliferative neoplasm characterized by increased numbers of peripheral monocytes and less than 20 percent blasts. CMML has few treatment options and patients only survive on average for 12 to 24 months.

29 May 2015

Researchers find weak spot in some antibiotic-resistant bacteria

Using a complex modeling program that helps analyze the physical dynamics of large, structurally complex protein molecules, a research team has made progress towards finding a weak spot in the architecture of a group of enzymes that are essential to antibiotic resistance in a number of bacteria.

29 May 2015

Green tea components may help prevent prostate cancer development in at-risk men

Prostate cancer is the second most common type of cancer in men and is predicted to result in an estimated 220,00 cases in the United States in 2015. In recent years, an emphasis has been placed on chemoprevention - the use of agents to prevent the development or progression of prostate cancer.

29 May 2015

Investigating epigenetic marks in ancient DNA could help understand health of ancient populations

A new study by anthropologists from The University of Texas at Austin shows for the first time that epigenetic marks on DNA can be detected in a large number of ancient human remains, which may lead to further understanding about the effects of famine and disease in the ancient world.

29 May 2015

Boehringer Ingelheim, University of Michigan partner to discover new medicines for diabetic nephropathy

Boehringer Ingelheim and the University of Michigan announce today that they have entered into a research collaboration focused on the discovery of new medicines for patients with diabetic nephropathy.

29 May 2015

Therapy for genetically-caused emphysema slows progression of lung disease

A landmark clinical study in the Lancet provides convincing evidence that a frequently overlooked therapy for genetically-caused emphysema is effective and slows the progression of lung disease.

29 May 2015

Healthcare workers serve as vector for MRSA transmission in nursing home settings

Healthcare workers frequently contaminate their gloves and gowns during every day care of nursing homes residents with drug resistant Staphylococcus aureus or MRSA, according to a new study. The findings were published online today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

29 May 2015

New study examines best practices in teaching medical students to better detect skin lesions

Each year, thousands of Canadians are given the news: they have skin cancer. It is the most common form of cancer in Canada and around the world, but if detected early, survival rates are extremely high. According to Liam Rourke, it doesn't happen nearly as often as it could.

29 May 2015

Sanford-Burnham, Takeda partner to develop new therapeutic targets for cardiovascular disease

Sanford-Burnham Medical Research Institute at Lake Nona today announced it has signed a two-year partnership agreement with Takeda Pharmaceutical Company Ltd. of Japan to study the potential role of several gene regulatory proteins as targets for the treatment of heart failure.

29 May 2015

Research News and Research

Amgen creates catalog of qualified tools and reagents to advance basic discoveries in biology

Study highlights recent trends in non-fatal suicidal events in the U.S. Army

DNA analysis reveals how ovarian cancer takes genetic twists and turns to outsmart chemotherapy

Incidence of melanoma on the rise among children and young adults

Poor sleep significantly decreases cognitive performance in autistic and neurotypical children

Study reveals new molecular mechanism that helps protect genome from harmful effect of UV radiations

Strategy-based cognitive training improves cognitive, psychological health after traumatic brain injury

UCLA researchers successfully measure liver function in potential organ donors using finger-probe device

Monoclonal antibody nivolumab improves survival rates of melanoma patients

MIT researchers find neural circuit that appears to cause decision-making in approach-avoidance conflict

MEDI4736 and tremelimumab combination shows acceptable safety, potential efficacy in NSCLC patients

JAK2 inhibitor ruxolitinib shows promise in treating CMML patients

Researchers find weak spot in some antibiotic-resistant bacteria

Green tea components may help prevent prostate cancer development in at-risk men

Investigating epigenetic marks in ancient DNA could help understand health of ancient populations

Boehringer Ingelheim, University of Michigan partner to discover new medicines for diabetic nephropathy

Therapy for genetically-caused emphysema slows progression of lung disease

Healthcare workers serve as vector for MRSA transmission in nursing home settings

New study examines best practices in teaching medical students to better detect skin lesions

Sanford-Burnham, Takeda partner to develop new therapeutic targets for cardiovascular disease

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