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Early intensive epoprostenol yields best haemodynamic outcomes in PAH

Patients with pulmonary arterial hypertension achieve greater improvements in right heart haemodynamics if epoprostenol is given rapidly and at a high dose, research suggests.

15 May 2015

New study shows safe levels of exercise differ for men and women with Atrial Firbrillation

Data from nearly 380,000 patients presented at Heart Rhythm 2015 reveals that moderate exercise is beneficial, yet vigorous exercise can increase the risk of AF for men

15 May 2015

Study finds botulinum toxin injections in epicardial fat pads reduce AF risk immediately following surgery and after one year of follow-up

AF is the most common arrhythmia complicating cardiac surgery and occurs in approximately 30-40 percent of patients undergoing CABG surgery...

15 May 2015

Study compares effectiveness of treatments for metastatic non-clear cell kidney cancers

A head-to-head comparison of two biologic therapies used to treat a subset of patients with advanced kidney cancers provides much-needed clarity on the preferred treatment for the first line of attack.

15 May 2015

New affordable advanced NGS cancer test launched by EKF subsidiary

This new NGS panel molecular test is an important step towards readily accessible and affordable personalized medicine in cancer...

From EKF Diagnostics 15 May 2015

Research leads way for noninvasive detection of early stage liver cancer

Led by Georgia State University, researchers have developed the first robust and noninvasive detection of early stage liver cancer and liver metastases, in addition to other liver diseases, such as cirrhosis and liver fibrosis.

15 May 2015

Researchers discover how and where chromosome fragile sites occur in human DNA

Using a novel method they developed to map chromosome breaks in a model organism, the budding yeast, Wenyi Feng, Ph.D., of Upstate Medical University and her colleagues have discovered new information as to how and where chromosome fragile sites can occur in human DNA. These sites are frequently observed in cancer cells and are responsible for causing genomic rearrangements.

15 May 2015

CASI Pharmaceuticals reports net loss of $1.8 million for first quarter 2015

CASI Pharmaceuticals, Inc., a biopharmaceutical company dedicated to the acquisition, development and commercialization of innovative therapeutics addressing cancer and other unmet medical needs for the global market with a commercial focus on China today reported financial results for the three months ended March 31, 2015.

15 May 2015

APS honors recipients of Clinical Centers of Excellence in Pain Management Awards

The American Pain Society today honored the recipients of its annual Clinical Centers of Excellence in Pain Management Awards recognizing the nation's outstanding pain care centers. Five multidisciplinary pain programs were recognized.

15 May 2015

Drug combination lengthens lives of metastatic colorectal cancer patients

A drug developed 50 years ago and abandoned because it was considered to be too toxic has gained a second life in an international clinical trial. Research led by scientists at Dana-Farber Cancer Institute showed the drug and a potentiating agent lengthened the lives of patients with metastatic colorectal cancer, all of whom had exhausted available standard treatments.

15 May 2015

Handshakes better than your blood pressure at assessing your health

The firmness of your hand grip is better than your blood pressure at assessing your health, Hamilton researchers have found, and reduced muscular strength, measured by your grip, is consistently linked with early death, disability and illness.

15 May 2015

New genomics laboratory in Liberia enables scientists to monitor genetic changes in Ebola virus

Army scientists working to support the Ebola virus outbreak response in West Africa have established the first genomic surveillance capability in Liberia, enabling them to monitor genetic changes in the virus within one week of sample collection. An article describing their work was recently published ahead of print in the online edition of Emerging Infectious Diseases.

15 May 2015

Results from four major studies on cancer treatments to be presented at ASCO Annual Meeting

The American Society of Clinical Oncology today announced results from four major studies to be presented at ASCO's 51st Annual Meeting, May 29-June 2, in Chicago. Findings showed that use of a widely available vitamin pill reduces the risk of non-melanoma skin cancers; that early chemotherapy extends the lives of men with advanced prostate cancers; and that new therapies can improve outcomes for children with a rare form of kidney cancer and adults with relapsed multiple myeloma.

15 May 2015

Vagus nerve stimulation effective in inhibiting cortical spreading depression

A poster presentation at the International Headache Congress in Valencia, Spain reports that VNS inhibits cortical spreading depression (CSD), which is known to be the cause of migraine aura and a trigger for headache.

15 May 2015

Mifepristone-eribulin combination clinically active in triple-negative breast cancer patients

Corcept Therapeutics Incorporated, a pharmaceutical company engaged in the discovery, development and commercialization of drugs that treat severe metabolic, oncologic and psychiatric disorders by modulating the effects of cortisol, today announced results of a multi-center Phase 1/2 dose-escalation study of mifepristone and chemotherapy drug eribulin (Halaven) that show it is well tolerated and clinically active in patients with triple-negative breast cancer.

15 May 2015

Sheffield scientists to showcase novel medical discoveries during International Clinical Trials Day

WORLD-leading researchers and scientists from Sheffield Teaching Hospitals Foundation Trust and the University of Sheffield will be giving people in Sheffield and beyond a unique insight into how they can contribute to groundbreaking medical discoveries during International Clinical Trials Day (Wednesday 20 May 2015).

15 May 2015

Itamar Medical provides comprehensive solution for obstructive sleep apnea to cardiologists

In light of the growing evidence of the link between cardiovascular disease and obstructive sleep apnea (OSA), Itamar Medical Ltd. is expanding its business model by offering a comprehensive sleep apnea management solution to cardiologists, who seek to create a streamlined pathway for effective treatment.

15 May 2015

Raising awareness of mouth and throat cancer increases screening in Florida's poorest counties

Raising awareness of the dangers of mouth and throat cancer increased the number of black men in some of Florida's poorest counties who sought screening for the first time, opening the door to improved survival rates through early detection and treatment, UF Health researchers report.

15 May 2015

Study evaluates prenatal nutrition and genome-wide DNA patterns in adults exposed to malnutrition

Researchers at Columbia University's Mailman School of Public Health and Leiden University in the Netherlands found that children whose mothers were malnourished at famine levels during the first 10 weeks of pregnancy had changes in DNA methylation known to suppress genes involved in growth, development, and metabolism documented at age 59.

15 May 2015

Combination of contraceptive and cholesterol-lowering drugs kills cancer cells in a new way

The combination of a cholesterol-lowering drug, Bezafibrate, and a contraceptive steroid, Medroxyprogesterone Acetate, could be an effective, non-toxic treatment for a range of cancers, researchers at the University of Birmingham have found.

15 May 2015

Research News and Research

Early intensive epoprostenol yields best haemodynamic outcomes in PAH

New study shows safe levels of exercise differ for men and women with Atrial Firbrillation

Study finds botulinum toxin injections in epicardial fat pads reduce AF risk immediately following surgery and after one year of follow-up

Study compares effectiveness of treatments for metastatic non-clear cell kidney cancers

New affordable advanced NGS cancer test launched by EKF subsidiary

Research leads way for noninvasive detection of early stage liver cancer

Researchers discover how and where chromosome fragile sites occur in human DNA

CASI Pharmaceuticals reports net loss of $1.8 million for first quarter 2015

APS honors recipients of Clinical Centers of Excellence in Pain Management Awards

Drug combination lengthens lives of metastatic colorectal cancer patients

Handshakes better than your blood pressure at assessing your health

New genomics laboratory in Liberia enables scientists to monitor genetic changes in Ebola virus

Results from four major studies on cancer treatments to be presented at ASCO Annual Meeting

Vagus nerve stimulation effective in inhibiting cortical spreading depression

Mifepristone-eribulin combination clinically active in triple-negative breast cancer patients

Sheffield scientists to showcase novel medical discoveries during International Clinical Trials Day

Itamar Medical provides comprehensive solution for obstructive sleep apnea to cardiologists

Raising awareness of mouth and throat cancer increases screening in Florida's poorest counties

Study evaluates prenatal nutrition and genome-wide DNA patterns in adults exposed to malnutrition

Combination of contraceptive and cholesterol-lowering drugs kills cancer cells in a new way

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