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New computational method identifies routes of cellular differentiation in acute myeloid leukemia

Researchers have developed a new method to distinguish between cancerous and healthy stem cells and progenitor cells from samples of patients with acute myeloid leukemia (AML), a disease driven by malignant blood stem cells that have historically been difficult to identify.

24 Apr 2023

Mount Sinai announces creation of the Institute for Regenerative Medicine

Regenerative medicine - the process of replacing, engineering or regenerating human cells, tissues or organs - holds exciting potential for the field of health care.

24 Apr 2023

Research findings could help inform more effective therapies for AML

Acute myeloid leukemia (AML) is a type of cancer in which the bone marrow makes a large number of abnormal blood cells. It is the most common type of acute leukemia in adults.

24 Apr 2023

Repair crews may move in to help fix the oxidative damage in protein factories

In a discovery fundamental to the inner workings of cells, scientists have discovered that if oxidative stress damages protein factories called ribosomes, repair crews may move in to help fix the damage so work can quickly resume.

24 Apr 2023

Mitophagy helps blood cancer cells to evade the killing effects of BH3 mimetic drug

Despite the promise of new medications that promote cancer cell death in people with acute myeloid leukemia, leukemic cells often adopt features that let them evade the drugs' effects within a year.

24 Apr 2023

Novel cell signaling pathway could be targeted against aggressive pancreatic cancers

Researchers at the Johns Hopkins Kimmel Cancer Center identified a novel cell signaling pathway that potentially could be targeted in therapy for patients with aggressive pancreatic cancers.

24 Apr 2023

Bioengineered drug candidate can counter S. aureus infection in early tests

Researchers at NYU Grossman School of Medicine and Janssen Biotech, Inc. have shown in early tests that a bioengineered drug candidate can counter infection with Staphylococcus aureus – a bacterial species widely resistant to antibiotics and a major cause of death in hospitalized patients.

24 Apr 2023

Discovery about inflammation ‘brake’ gene paves way to personalized treatments for kidney disease

A discovery about gene variants of an inflammation 'brake' brings scientists a step closer to personalised treatment for patients at risk of kidney disease and kidney failure.

24 Apr 2023

Researchers discover a key player in preventing 'insulin shock'

Just over a century has passed since the discovery of insulin, a time period during which the therapeutic powers of the hormone have broadened and refined. Insulin is an essential treatment for type 1 diabetes and often for type 2 diabetes, as well.

24 Apr 2023

Sphere Fluidics begins work with partners on 3DSecret program to investigate mechanisms of metastasis in cancer

Sphere Fluidics announced its involvement in 3DSecret.

From Fluidic Sciences and Sphere Bio 24 Apr 2023

Revolutionizing Glycobiology: A Mass Spectrometrist's Perspective

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to Professor Albert Heck and gained a mass spectrometrist's perspective on the field of glycobiology.

From Pittcon 24 Apr 2023

Deciphering immunological imprinting in the context of COVID-19

In a recent article published in the journal Immunity, researchers explained the concept of immunological imprinting and its underlying principles. They also discussed its potential role in the context of coronavirus disease 2019 (COVID-19) vaccines.

24 Apr 2023

What are the gastrointestinal benefits of consuming soybean?

In a recent review published in the journal Nutrients, researchers at Australia’s CSIRO reviewed existing literature on the nutritional implications of soy intake concerning the intestinal microbiome.

23 Apr 2023

Novel self-amplifying RNA vaccine confers durable protection against COVID-19, reduces viral shedding in primate study

A self-amplifying replicon RNA vaccine against SARS-CoV-2 can elicit durable and protective immunity in pigtail macaques, even after neutralizing antibody responses have waned to undetectable levels.

23 Apr 2023

Underrepresentation of women in research studies correlates with lack of female scientists

The underrepresentation of female research subjects has been documented from clinical trials down to sources for cell cultures.

21 Apr 2023

Researchers develop a backpack-based myeloid cell therapy for MS patients

Multiple sclerosis (MS) is a devastating autoimmune disease that destroys the protective myelin covering around nerves, disrupting communication between the brain and body, and causing patients' ability to move and function to progressively decline.

21 Apr 2023

New tool offers high accuracy in the interpretation of genetic mutations in disease genes

Despite the increasing use of genomic sequencing in clinical practice, interpreting rare genetic mutations, even among well-studied disease genes, remains difficult.

21 Apr 2023

New injectable cell therapy shows promise for treating osteoarthritis

Wake Forest Institute for Regenerative Medicine (WFIRM) scientists have created a promising injectable cell therapy to treat osteoarthritis that both reduces inflammation and also regenerates articular cartilage.

21 Apr 2023

Researchers identify a type of immune cell that drives chronic organ transplant failure

University of Pittsburgh researchers have identified a type of immune cell that drives chronic organ transplant failure in a mouse model of kidney transplantation and uncovered pathways that could be therapeutically targeted to improve patient outcomes.

21 Apr 2023

Weight loss surgery more effective for the treatment of non-alcoholic fatty liver disease

Metabolic (bariatric) surgery is more effective than medications and lifestyle interventions for the treatment of advanced non-alcoholic fatty liver disease.

21 Apr 2023

Cell News and Research

New computational method identifies routes of cellular differentiation in acute myeloid leukemia

Mount Sinai announces creation of the Institute for Regenerative Medicine

Research findings could help inform more effective therapies for AML

Repair crews may move in to help fix the oxidative damage in protein factories

Mitophagy helps blood cancer cells to evade the killing effects of BH3 mimetic drug

Novel cell signaling pathway could be targeted against aggressive pancreatic cancers

Bioengineered drug candidate can counter S. aureus infection in early tests

Discovery about inflammation ‘brake’ gene paves way to personalized treatments for kidney disease

Researchers discover a key player in preventing 'insulin shock'

Sphere Fluidics begins work with partners on 3DSecret program to investigate mechanisms of metastasis in cancer

Revolutionizing Glycobiology: A Mass Spectrometrist's Perspective

Deciphering immunological imprinting in the context of COVID-19

What are the gastrointestinal benefits of consuming soybean?

Novel self-amplifying RNA vaccine confers durable protection against COVID-19, reduces viral shedding in primate study

Underrepresentation of women in research studies correlates with lack of female scientists

Researchers develop a backpack-based myeloid cell therapy for MS patients

New tool offers high accuracy in the interpretation of genetic mutations in disease genes

New injectable cell therapy shows promise for treating osteoarthritis

Researchers identify a type of immune cell that drives chronic organ transplant failure

Weight loss surgery more effective for the treatment of non-alcoholic fatty liver disease

What are the challenges of cell line development? eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo