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FDA clears Insmed IND for ARIKACE Phase 3 clinical trial in nontuberculous mycobacteria lung infections

Insmed Incorporated, a biopharmaceutical company, announced today that the Company's Investigational New Drug Application (IND) to conduct a pivotal Phase 3 clinical trial of ARIKACE™ (liposomal amikacin for inhalation) in nontuberculous mycobacteria (NTM) lung infections has been cleared by the U.S. Food and Drug Administration (FDA).

21 Mar 2011

NanoViricides reports improved efficacy with optimized FluCide nanoviricide drug candidates for influenza

NanoViricides, Inc. reported dramatically improved antiviral efficacy with its optimized FluCide™ drug candidates in its most recent animal study.

21 Mar 2011

Researchers discover 'broad spectrum' cancer suppressor gene

Portuguese researchers have discovered a "broad spectrum" cancer suppressor gene - called LRP1B - which acts by removing proteins crucial for cancer development from the tumour environment. The fact that LRP1B does not act on the tumour itself (in this study thyroid tumours) but, instead, on molecules which are known to be important to many different cancers is what makes it so interesting.

21 Mar 2011

Asthma an diabetes go hand in hand: Research

A new study has found that people with asthma may have a higher risk of developing diabetes and heart disease. The study looked at the relationship between asthma and four other inflammatory conditions.

21 Mar 2011

FDA meets ambitious implementation deadlines set forth in tobacco law

Since the passage of the Family Smoking Prevention and Tobacco Control Act in 2009, the U.S. Food and Drug Administration has met the ambitious implementation deadlines set forth in the law, the agency said Wednesday at a congressional briefing hosted by the American Association for Cancer Research.

19 Mar 2011

Deaths from heart attacks drop precipitously in Norway, reports NTNU researcher

Life was hard in occupied Norway during WWII, but the occupation had one surprising result: deaths from heart attacks dropped precipitously, because Norwegians ate less fat, smoked less and were more physically active.

19 Mar 2011

Journal of Clinical Lipidology publishes LipoScience LDL particle study results against CVD

LipoScience, Inc., a highly innovative diagnostic company that is advancing patient care by developing high value proprietary blood tests using nuclear magnetic resonance technology, today announced publication of a clinical study in the Journal of Clinical Lipidology demonstrating that in many people, low density lipoprotein cholesterol is a less accurate predictor of cardiovascular disease events than LDL particle number.

19 Mar 2011

Removal of menthol cigarettes from marketplace would benefit public health in US: FDA

Finding that the availability of menthol cigarettes increases the number of children and African Americans who smoke, the Food and Drug Administration's Tobacco Products Scientific Advisory Committee today concluded, "Removal of menthol cigarettes from the marketplace would benefit public health in the United States."

19 Mar 2011

Polaris initiates ADI-PEG 20 Phase 2 trial in patients with malignant mesothelioma

Polaris Group announced today the enrollment of the first patient in a Phase 2 clinical trial of ADI-PEG 20, the company's novel enzyme-based treatment for malignant mesothelioma.

19 Mar 2011

Researchers identify protein that triggers immune response in TB-infected people

Scientists have discovered a protein secreted by tuberculosis bacteria that could be a promising new vaccine candidate, they report today in Proceedings of the National Academy of Sciences. The protein could also be used to improve diagnosis of TB.

19 Mar 2011

[UPDATE] Pediatric heart surgery unit of Royal Brompton faces closure

A London NHS trust would challenge proposals to end child heart surgery at the Royal Brompton Hospital. The Royal Brompton and Harefield NHS Foundation Trust added that this would mean the loss of other services, which could call into question its viability.

18 Mar 2011

Englewood Hospital and Medical Center earns HealthGrades Patient Safety Excellence Award

Englewood Hospital and Medical Center was identified as a recipient of the 2011 HealthGrades Patient Safety Excellence Award, indicating that its patient safety ratings are in the top 5% of U.S. hospitals.

18 Mar 2011

U-M researcher endorses new concepts designed to improve kidney allocation

Providing kidney transplants to patients with the best probability of longer survival would reduce repeat transplant operations and improve life span after kidney transplant, says a U-M researcher in a commentary published in the New England Journal of Medicine March 16.

18 Mar 2011

Conference addresses health and safety hazards in homes

Millions of U.S. families face health and safety hazards like mold, lead, pest infestation and the physical deterioration of their homes. These problems are particularly common among some of the nation's most vulnerable populations: children, seniors, the disabled and low-income families.

18 Mar 2011

CPF applauds new guidelines for treatment of idiopathic pulmonary fibrosis

The Coalition for Pulmonary Fibrosis (CPF) applauds the joint statement issued by the American Thoracic Society for the first evidence-based clinical guidelines for the treatment of idiopathic pulmonary fibrosis (IPF). The guidelines represent progress in understanding of the disease and a milestone for patients. The devastating and deadly disease also called simply "Pulmonary Fibrosis" or "PF" has no FDA approved treatment and no cure.

18 Mar 2011

Study sheds light on how vitamin A contributes to immune responses in gastrointestinal tract

Although it has been known for some time that vitamin A deficiency is linked with an impaired ability to resist infections, exactly how vitamin A and its metabolites contribute to the immune response is not well understood.

18 Mar 2011

New drug can aid in smoking reduction therapy

Researchers working in a research project within the Academy of Finland's Research Programme on Substance Use and Addictions have been developing a targeted drug that could aid in smoking reduction therapy. The new drug slows down the metabolism of nicotine, which would help smokers to cut down their smoking.

18 Mar 2011

CytRx commences INNO-206 Phase 1b trial in advanced solid tumors

CytRx Corporation, a biopharmaceutical company specializing in oncology, today announced that it has initiated an open-label Phase 1b safety and dose escalation clinical trial with INNO-206 at the Sarcoma Oncology Center in Santa Monica, California. The clinical trial will include up to 24 patients with advanced solid tumors who have failed standard therapies.

17 Mar 2011

PsiOxus commences MT-102 Phase II study for treatment of cancer- and age-related wasting

PsiOxus Therapeutics, Ltd. announced initiation of a Phase II study of MT-102, a small molecule therapeutic for the treatment of cancer- and age-related wasting. MT-102 is being developed to reverse the effects of cachexia, a wasting disease that accompanies cancer, heart failure, COPD, renal failure, cirrhosis and rheumatoid arthritis, and that is associated with significant morbidity and mortality.

17 Mar 2011

Scientist suggests breaking tangled mucus barrier can help treat cancer

Measuring the mechanical strength of cancer cell mucus layers provides clues about better ways to treat cancer, and also suggests why some cancer cells are more resistant to drugs than others, according to Kai-tak Wan, associate professor of engineering at Northeastern University, Boston, Mass.

17 Mar 2011

Lungs News and Research

FDA clears Insmed IND for ARIKACE Phase 3 clinical trial in nontuberculous mycobacteria lung infections

NanoViricides reports improved efficacy with optimized FluCide nanoviricide drug candidates for influenza

Researchers discover 'broad spectrum' cancer suppressor gene

Asthma an diabetes go hand in hand: Research

FDA meets ambitious implementation deadlines set forth in tobacco law

Deaths from heart attacks drop precipitously in Norway, reports NTNU researcher

Journal of Clinical Lipidology publishes LipoScience LDL particle study results against CVD

Removal of menthol cigarettes from marketplace would benefit public health in US: FDA

Polaris initiates ADI-PEG 20 Phase 2 trial in patients with malignant mesothelioma

Researchers identify protein that triggers immune response in TB-infected people

[UPDATE] Pediatric heart surgery unit of Royal Brompton faces closure

Englewood Hospital and Medical Center earns HealthGrades Patient Safety Excellence Award

U-M researcher endorses new concepts designed to improve kidney allocation

Conference addresses health and safety hazards in homes

CPF applauds new guidelines for treatment of idiopathic pulmonary fibrosis

Study sheds light on how vitamin A contributes to immune responses in gastrointestinal tract

New drug can aid in smoking reduction therapy

CytRx commences INNO-206 Phase 1b trial in advanced solid tumors

PsiOxus commences MT-102 Phase II study for treatment of cancer- and age-related wasting

Scientist suggests breaking tangled mucus barrier can help treat cancer

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