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Cloning stem cells to develop treatments for Crohn's disease

For over a decade Wa Xian, research associate professor of biology and biochemistry at the University of Houston Stem Cell Center, has been perfecting technology for cloning stem cells. Now she is using it to take aim at pediatric Crohn's disease.

18 Jun 2020

Discovery of key steps in kidney formation could have implications for treating renal diseases

The discovery of how certain key structures in the kidneys are formed could have important implications for treating renal fibrosis (or scarring), a feature of chronic kidney disease (CKD), according to a new study by a researcher at Massachusetts General Hospital.

18 Jun 2020

Research uncovers some of the secrets to longevity

University of Otago researchers have discovered some of the secrets to longevity with new research revealing not smoking and being social engaged throughout older age are common traits of New Zealand centenarians.

18 Jun 2020

Staffing levels and quality linked to COVID-19 toll in nursing homes

A new study shows that residents of long-term care facilities with lower nurse staffing levels, poorer quality scores, and higher concentrations of disadvantaged residents suffer from higher rates of confirmed COVID-19 cases and deaths.

18 Jun 2020

COVID-19 and blood group in aortic valve replacement

The COVID-19 pandemic has been found to cause disproportionate harm in patients with cardiovascular disease, especially among the elderly population, among other risk factors. However, a new study published on the preprint server medRxiv* in June 2020 is the first to report its clinical features in patients with aortic stenosis who have had a transcatheter aortic valve replacement (TAVR).

18 Jun 2020

Scientists develop peptides that restore balance in gut bacteria and reverse atherosclerosis

Now, a team of scientists at Scripps Research has developed new molecules that can restore the balance in gut bacteria in the intestines and as a result, lowers cholesterol levels and reverses the narrowing of the arteries, also known as atherosclerosis.

18 Jun 2020

COVID-19 could trigger diabetes in healthy people

The coronavirus disease (COVID-19) causes severe illness in people with underlying health conditions, such as heart disease, hypertension, lung illness, and diabetes. Now, scientists warn that viral infection may trigger the development of diabetes in healthy people.

18 Jun 2020

ACE2 and pattern recognition receptor genes increase with age

A recent study by researchers in California and published on the preprint server bioRxiv* in June 2020 shows that advancing age is associated with increased expression of pattern recognition receptor (PRR) genes and ACE2 receptors, possibly accounting in part for the increased severity of the disease in older adults.

17 Jun 2020

Study investigates effectiveness of liver perfusion to improve the function of donor livers

A major study investigating the effectiveness of liver perfusion as a technique to improve the function of donor livers that would have otherwise been rejected has shown that up to 7 in every 10 could be used after just 4-6 hours of the assessment.

17 Jun 2020

Study: Nearly 10% of patients continue to use opioids more than 90 days after heart surgery

Nearly 10 percent of patients who are prescribed opioid medications following heart surgery will continue to use opioids more than 90 days after the procedure, according to a new study led by researchers in the Perelman School of Medicine at the University of Pennsylvania.

17 Jun 2020

New nanoparticle drug combination can help treat atherosclerosis

Physicochemical cargo-switching nanoparticles (CSNP) designed by KAIST can help significantly reduce cholesterol and macrophage foam cells in arteries, which are the two main triggers for atherosclerotic plaque and inflammation.

17 Jun 2020

Pandemic upends the lives of people with disabilities — and of their caregivers

When the COVID-19 pandemic hit, Stacy Ellingen, 34, of Oshkosh, Wisconsin, lost two of the three caregivers she depends on to dress, shower, eat and use the bathroom. The caregivers — both University of Wisconsin-Oshkosh students — returned to their parents’ homes when the university canceled in-person classes.

17 Jun 2020

Scientists use fMRI to explain why people are still lonely even if they are around others

Social connection is essential to one's well-being, but how the brain reflects a person's attachment to other people remains unclear. Now, a team of researchers has found that loneliness can alter the brain's social network, explaining how the brain represents relationships.

17 Jun 2020

Researchers create superior bone grafts using primitive stem cells

Although most broken bones can be mended with a firm cast and a generous measure of tender loving care, more complicated fractures require treatments like bone grafting.

16 Jun 2020

Novel antisense drug shows promise to improve health of people with NAFLD

Using a first-of-its-class drug in a clinical trial, an international research effort headed by a scientist at University of California San Diego School of Medicine reports that inhibition of a key enzyme safely and effectively improved the health of persons with non-alcoholic fatty liver disease, a chronic metabolic disorder that affects hundreds of millions of people worldwide.

16 Jun 2020

UCLA receives nearly $14 million NIH grant to investigate immunotherapy to destroy HIV

UCLA researchers and colleagues have received a $13.65 million grant from the National Institutes of Health to investigate and further develop an immunotherapy known as CAR T, which uses genetically modified stem cells to target and destroy HIV.

16 Jun 2020

Cell signaling pathway could treat chronic kidney disease and other medical conditions

Scientists have discovered an important cell signaling pathway in the kidney which if stopped, could hold the key to treating chronic kidney disease as well as other deadly conditions, including heart attack and stroke.

16 Jun 2020

Scientists develop self-assessment tool for evaluation and treatment of COVID-19

Of the more than 275,000 people worldwide who accessed a USC web-based COVID-19 patient self-assessment tool, only 20 percent reported severe symptoms requiring immediate medical attention, according to new research published in the Journal of General Internal Medicine.

16 Jun 2020

Survey: Low income Vermonters have been disproportionately affected by COVID-19

High percentages of Vermonters agree with the social distancing measures put in place by the state in response to the coronavirus pandemic and have complied with them, according to a new survey.

16 Jun 2020

Inhaled steroids reduce ACE2 expression in COPD lungs

A new study by scientists at Imperial College London, University of Newcastle and Prokarium, and published on the preprint server bioRxiv* in June 2020 examines the role played by inhaled corticosteroids (ICS) in the risk of acquisition of COVID-19 infection by COPD patients.

15 Jun 2020

Chronic News and Research

Cloning stem cells to develop treatments for Crohn's disease

Discovery of key steps in kidney formation could have implications for treating renal diseases

Research uncovers some of the secrets to longevity

Staffing levels and quality linked to COVID-19 toll in nursing homes

COVID-19 and blood group in aortic valve replacement

Scientists develop peptides that restore balance in gut bacteria and reverse atherosclerosis

COVID-19 could trigger diabetes in healthy people

ACE2 and pattern recognition receptor genes increase with age

Study investigates effectiveness of liver perfusion to improve the function of donor livers

Study: Nearly 10% of patients continue to use opioids more than 90 days after heart surgery

New nanoparticle drug combination can help treat atherosclerosis

Pandemic upends the lives of people with disabilities — and of their caregivers

Scientists use fMRI to explain why people are still lonely even if they are around others

Researchers create superior bone grafts using primitive stem cells

Novel antisense drug shows promise to improve health of people with NAFLD

UCLA receives nearly $14 million NIH grant to investigate immunotherapy to destroy HIV

Cell signaling pathway could treat chronic kidney disease and other medical conditions

Scientists develop self-assessment tool for evaluation and treatment of COVID-19

Survey: Low income Vermonters have been disproportionately affected by COVID-19

Inhaled steroids reduce ACE2 expression in COPD lungs

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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