Inflammation News and Research

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Scientists uncover link between backup pathogen-fighting system and mutations in Crohn's patients

Genes that regulate a cellular recycling system called autophagy are commonly mutated in Crohn's disease patients, though the link between biological housekeeping and inflammatory bowel disease remained a mystery. Now, researchers at UT Southwestern Medical Center have uncovered an intriguing clue.

28 Jul 2017

UA researchers seek to better understand NHE8 protein’s role in GI disorders, colon cancer

About 1.6 million Americans suffer from inflammatory bowel disease (IBD), which encompasses several painful and complex disorders that include Crohn's disease and ulcerative colitis.

27 Jul 2017

New approach may improve translation of immunological research findings

Mouse models have advanced our understanding of immune function and disease in many ways but they have failed to account for the natural diversity in human immune responses.

27 Jul 2017

Stem cells in the brain found to influence aging in mice

A study conducted by a team of researchers led by Dongsheng Cai at the Albert Einstein College of Medicine, New York, finds that injecting extra stem cells into the hypothalamus in the brain of mice slows down the aging process.

27 Jul 2017

New discovery could aid in synthesis of radiotracers for use with PET scanning

Researchers have found a surprisingly versatile workaround to create chemical compounds that could prove useful for medical imaging and drug development.

27 Jul 2017

UGA researcher develops clinical decision rule to accurately detect acute bacterial rhinosinusitis

Sinus infections are one of the most common reasons patients walk out of the doctor's office with an antibiotic prescription in hand. The problem is that bacteria causes only about one-third of sinus infections, which means most patients are inappropriately receiving antibiotics.

26 Jul 2017

Study provides fresh insights into how the body detects early signs of cancer

Fresh insights into how cells detect damage to their DNA - a hallmark of cancer - could help explain how the body keeps disease in check.

26 Jul 2017

Genetic test to predict IBD severity in children

Inflammatory bowel disease (IBD) is a chronic relapsing inflammation of the gastrointestinal tract with abdominal pain and diarrhea being the most common symptoms. It can be challenging to diagnose as gastrointestinal complaints mimicking IBD are common.

26 Jul 2017

Effects of declining sperm counts on fertility, mortality and disease patterns in geographical areas: Study

There is a lack of definitive data on the actual trends of decline in sperm counts according to researchers despite it being a known fact. Researchers in a new study looked at a large population to find the exact data regarding this scenario and its effects on the society. They looked at the effects of fertility and geographical distribution on the sperm concentration as well as total sperm counts.

25 Jul 2017

Living in rural households lowers person's risk of developing IBD, study finds

Living in rural households decreases a person's risk of developing inflammatory bowel disease (IBD), particularly for young children and adolescents, according to a new study by researchers at the Children's Hospital of Eastern Ontario Research Institute, Institute for Clinical Evaluative Sciences, and the Canadian Gastro-Intestinal Epidemiology Consortium.

25 Jul 2017

Joint research initiative aims to employ novel lifestyle intervention to treat NAFLD

Non-alcoholic fatty liver disease (NAFLD) is one of the most frequent liver diseases worldwide and an estimated 20 million people in Germany are affected.

25 Jul 2017

Researchers understand how to prevent severe weight loss in cancer patients

Many cancer patients are susceptible to potentially lethal weight loss. Now researchers understand better why this happens, and perhaps how to prevent the condition.

25 Jul 2017

Low vitamin D may affect recovery of injured corneas

Injury or disease in combination with too little vitamin D can be bad for the window to your eyes. The three-layer, transparent cornea at the front of the eyes focuses the light coming in. But its prominent position also puts it at risk for injury from an errant mascara wand or over-prodding finger or a car accident.

24 Jul 2017

Research shows alarming prevalence of overfat pandemic in developed countries

Does your waist measure more than half your height? If so, you may be part of the global overfat pandemic.

24 Jul 2017

New trial shows ketamine's effectiveness to treat geriatric depression

Australian researchers have completed the world's first randomised control trial (RCT) assessing the efficacy and safety of ketamine as a treatment for depression in elderly patients.

24 Jul 2017

Established therapeutic drugs may be effective against childhood dementia

Although dementia is most often seen in adults, childhood or adolescent dementia does occur. A team of researchers from the University of Würzburg believes that established therapeutic drugs might be effective against childhood dementia.

24 Jul 2017

Drowning can occur even while on dry land

Drowning is one of the biggest problems in the United States, and considering the number of people who will head to bodies of water to cool off this summer, we are entering the riskiest months.

21 Jul 2017

Genetic variation linked to greater tuberculosis susceptibility

Researchers have shown that a single nucleotide change in a gene that affects production of hepcidin--a peptide involved in inflammation, immunity, and control of iron levels--is associated with greater susceptibility to extrapulmonary tuberculosis.

21 Jul 2017

Testing treatments using pig model may help minimize drug failure rates for chronic conditions

Scientists may be able to minimize the failure rate of drugs for diseases linked to high-calorie diets, such as colon cancer and type 2 diabetes, if they test treatments using a pig model, according to an international team of researchers.

21 Jul 2017

Researchers find new way to protect stem cells from inflammation during wound repair

Scientists have found a new way to protect stem cells from harsh inflammation during wound repair. In a study recently published in the journal Cytotherapy, researchers in India discovered that treating mice with a common anti-inflammatory drug called celecoxib promoted stem cell survival and healing when they injected the cells into wounds.

20 Jul 2017