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Researchers identify mechanism for formation of rare colorectal cancer subtype

Researchers from Rutgers Cancer Institute of New Jersey, the state's only National Cancer Institute-designated Comprehensive Cancer Center, recently discovered a mechanism to explain what drives the formation of mucinous colorectal adenocarcinoma (MAC), a rare subtype of colorectal cancer (CRC), and has also identified the genes responsible for the regulation of this mechanism.

25 Aug 2021

Lowering blood pressure through Mediterranean diet and fitness may limit erectile dysfunction

Dietary and fitness habits have been shown to play a significant role in erectile performance and could improve erectile performance.

25 Aug 2021

Penn study shows how certain proteins have evolved to suppress cheating chromosomes

Eggs and sperm are special cells for many reasons, but one of the characteristics that sets them apart is that, unlike other human cells, which have two copies of 23 chromosomes, one from the mother and one from the father, these sex cells, or gametes, have only one.

25 Aug 2021

Enzyme related to rattlesnake neurotoxin linked with COVID-19 infection severity

Study shows that an enzyme may be a key mechanism driving COVID-19 severity and could provide a new therapeutic target.

25 Aug 2021

Research highlights the potential benefits of SARS-CoV-2 S gene mutants as immunogens

Previous research has shown that the spike (S) protein of -CoV-2 binds to a host cell receptor, facilitating viral entry.

25 Aug 2021

Researchers identify numerous genetic regions that may affect individuals' food intake

A team of researchers at Massachusetts General Hospital, Boston University School of Public Health, and other institutions have identified more than two dozen genetic regions that may affect individuals' food intake.

25 Aug 2021

Study could provide a new therapeutic target to reduce COVID-19 mortality

An enzyme with an elusive role in severe inflammation may be a key mechanism driving COVID-19 severity and could provide a new therapeutic target to reduce COVID-19 mortality, according to a study published in the Journal of Clinical Investigation.

25 Aug 2021

Two studies on gastrointestinal stroma tumors describe advances that may lead to new treatments

Gastrointestinal stroma tumors (GIST) are cancers that start in specialized nerve cells found in the digestive system, from the esophagus and stomach to the intestines and rectum.

25 Aug 2021

SARS-CoV-2 Delta likely to acquire resistance to wild-type spike vaccines

A new study published on the preprint server bioRxiv* explores the mechanism of the Delta variant's high infectivity and suggests a plausible pathway by which the Delta variant could escape from vaccine-induced immunity.

24 Aug 2021

Compounds from medicinal mushrooms may be our future weapon against SARS-CoV-2

Certain steroid-like compounds from Taiwan's endemic medicinal mushrooms (known as antcins) may inhibit a host cell receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and, thus, prevent viral infection and subsequent development of the coronavirus disease (COVID-19), reports a new study published in the MDPI's journal Plants.

24 Aug 2021

Study finds a new line of drugs to stimulate myelin repair in multiple sclerosis

In the nearly 1 million Americans living with multiple sclerosis, the fatty substance that insulates the nerves of the central nervous system—called myelin—is damaged.

24 Aug 2021

Researchers find clues to how lung damage develops in the aftermath of a respiratory infection

The deadliest time in a viral respiratory illness sometimes is actually after the virus is cleared from the body. Destructive processes that are set in motion during an infection crest in the weeks after the virus is defeated, leading to organ damage that can cause chronic illness or even death.

24 Aug 2021

Study suggests a balanced approach to developing safer opioid analgesics

Opioids are powerful painkillers but their use is hindered because patients become tolerant to them, requiring higher and higher doses, and overdoses can cause respiratory depression and death.

24 Aug 2021

Glycyrrhizic acid as a drug candidate for COVID-19

A new study presents the benefits of licorice, an age-old herbal remedy, to treat COVID-19 at all stages.

24 Aug 2021

UCLA scientists receive $1 million translational award to advance CAR T cell therapy for rare melanomas

Scientists Dr. Cristina Puig-Saus and Dr. Daniel Shin from the UCLA Jonsson Comprehensive Cancer Center have received a $1 million Translational Research Award from the U.S. Department of Defense Melanoma Research Program to help advance the use of chimeric antigen receptor, or CAR, T cell therapy as a treatment for people with acral, mucosal and uveal melanomas.

24 Aug 2021

Lack of inflammatory genes makes carnivores the biggest carriers of zoonotic pathogens

Carnivorous animals lack key genes needed to detect and respond to infection by pathogens, a study has found.

24 Aug 2021

First-in-kind kidney cancer drug developed at UTSW receives FDA approval

A first-in-kind kidney cancer drug developed from laboratory and translational studies conducted at UT Southwestern Medical Center received approval from the Food and Drug Administration, providing a new treatment for patients with familial kidney cancer.

24 Aug 2021

Researchers discover molecule that plays an important role in sperm motility regulation

About 120 million unintended pregnancies occurred each year between 2015 and 2019 worldwide. While there are oral contraceptives for women, the development of oral contraceptives for men has not been successful.

24 Aug 2021

Atomic-level imaging of infectious prions reveals new therapeutic targets for untreatable diseases

The highest-ever resolution imaging of an infectious prion provides the first atomic-level data of how these abnormal proteins are assembled to cause fatal neurodegenerative diseases in people and animals - and how they can be potentially targeted by new therapies.

24 Aug 2021

Frameshift deletion mutation in ORF7a may provide fitness advantage to Australia's SARS-CoV-2 delta variants

A team of scientists from Australia has recently identified a frameshift deletion mutation in ORF7a of the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The mutation results in the production of a truncated peptide with altered functionality. The study is currently available on the medRxiv* preprint server while awaiting peer review.

24 Aug 2021

Protein C News and Research

Researchers identify mechanism for formation of rare colorectal cancer subtype

Lowering blood pressure through Mediterranean diet and fitness may limit erectile dysfunction

Penn study shows how certain proteins have evolved to suppress cheating chromosomes

Enzyme related to rattlesnake neurotoxin linked with COVID-19 infection severity

Research highlights the potential benefits of SARS-CoV-2 S gene mutants as immunogens

Researchers identify numerous genetic regions that may affect individuals' food intake

Study could provide a new therapeutic target to reduce COVID-19 mortality

Two studies on gastrointestinal stroma tumors describe advances that may lead to new treatments

SARS-CoV-2 Delta likely to acquire resistance to wild-type spike vaccines

Compounds from medicinal mushrooms may be our future weapon against SARS-CoV-2

Study finds a new line of drugs to stimulate myelin repair in multiple sclerosis

Researchers find clues to how lung damage develops in the aftermath of a respiratory infection

Study suggests a balanced approach to developing safer opioid analgesics

Glycyrrhizic acid as a drug candidate for COVID-19

UCLA scientists receive $1 million translational award to advance CAR T cell therapy for rare melanomas

Lack of inflammatory genes makes carnivores the biggest carriers of zoonotic pathogens

First-in-kind kidney cancer drug developed at UTSW receives FDA approval

Researchers discover molecule that plays an important role in sperm motility regulation

Atomic-level imaging of infectious prions reveals new therapeutic targets for untreatable diseases

Frameshift deletion mutation in ORF7a may provide fitness advantage to Australia's SARS-CoV-2 delta variants

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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