Cell Division News and Research

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Eribulin from marine sponge inhibits replication of breast cancer cells

For more than three decades a new drug for the treatment of breast cancer had not been presented. A group of researchers were given the task of analyzing a marine sponge called Halichondrin okadai and obtained a mesylate eribulin substance that had already been applied to patients with this disease in the stage of metastasis, ie, when the disease spreads to other body parts and the result was that it inhibited tumor growth.

4 May 2015

TAXIS Pharmaceuticals' TXA709 compound shows promise in combating antibiotic resistance

TAXIS Pharmaceuticals, a drug-discovery company focused on developing a new class of antibiotic agents to treat life-threatening, multidrug-resistant bacterial infections, today announced the presentation of data demonstrating the promise of its lead clinical candidate, TXA709, in combating antibiotic resistance.

27 Apr 2015

Scientists identify possible new genes that could change benign skin growths into fatal melanomas

A Houston Methodist-led team of international scientists has identified hundreds of possible new genes in mice that could transform benign skin growths into deadly melanomas.

24 Apr 2015

UC Davis assistant professor wins Hartwell Foundation award to explore treatment for juvenile diabetes

UC Davis Assistant Professor Mark Huising is a recipient of The Hartwell Foundation 2014 Individual Biomedical Research Award to support his early-stage research toward a cure for juvenile diabetes. Diabetes affects 10 percent of the entire United States population, including approximately a million children. Remarkably, 40 children every day receive the diagnosis of diabetes.

22 Apr 2015

Study confirms that coffee inhibits growth of tumours, reduces risk of breast cancer recurrence

A number of research studies have shown that coffee helps to protect against breast cancer. A new study led by Lund University, has confirmed that coffee inhibits the growth of tumours and reduces the risk of recurrence in women who have been diagnosed with breast cancer and treated with the drug tamoxifen.

21 Apr 2015

Global changes in cancer cells' epigenome may determine disease progression

Genomic studies have illuminated the ways in which malfunctioning genes can drive cancer growth while stunting the therapeutic effects of chemotherapy and other treatments. But new findings from Weill Cornell Medical College investigators indicate that these genes are only partly to blame for why treatment that was at one point effective ultimately fails for about 40 percent of patients diagnosed with the most common form of non-Hodgkin Lymphoma.

21 Apr 2015

Myc cancer gene allows tumor cells to divide, provokes cell suicide process

Myc cancer gene empowers tumor cells to relentlessly divide but simultaneously, provokes a cell suicide process called apoptosis. Myc controls cells by commanding the expression of every tenth of the genes in the nucleus of a tumor cell. However, in spite of more than two decades of intense research, no Myc motivated killer genes have been found.

21 Apr 2015

New method for measuring genetic variability may help identify patients with aggressive cancers

A new method for measuring genetic variability within a tumor might one day help doctors identify patients with aggressive cancers that are more likely to resist therapy, according to a study led by researchers now at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

17 Apr 2015

Genetically modified Salmonella can help kill cancer cells

A new study has demonstrated that genetically modified Salmonella can be used to kill cancer cells. The study is published in this week's issue of mBio, an American Society for Microbiology online-only, open access journal.

15 Apr 2015

UC Davis researchers unravel how micro RNA could potentially lead to novel cancer therapies

The micro RNA miR-22 has long been known for its ability to suppress cancer. However, questions remain about how it achieves this feat. For example, which molecules are regulating miR-22, and which are miR22 targets?

6 Apr 2015

Dartmouth researchers use new strategies to target drug-resistant pathogens

By engineering antibacterial enzymes, Dartmouth investigators led by Karl Griswold, PhD are using novel strategies to target the prevalent drug-resistant bacterium Staphylococcus aureus.

3 Apr 2015

Mitochondrial DNA movement: an interview with Professor Jiri Neuzil, Griffith University

According to our understanding, mitochondria undergo cycles of fusion-fission, i.e. they divide within the constraints of a cell and, upon cell division, each of the two daughter cells gets its ‘share’ of mitochondria.

29 Mar 2015

Duke researchers develop new model to study why some HPV infections go away and others progress

For people infected with the human papilloma virus (HPV), the likelihood of clearing the infection and avoiding HPV-related cancer may depend less on the body's disease-fighting arsenal than has been generally assumed.

25 Mar 2015

Penn researchers find evidence of new culprit in colon cancer

Colon cancer is a heavily studied disease -- and for good reason. It is one of the leading causes of cancer-related deaths worldwide, and its numbers are on the rise, from 500,00 deaths in 1990 to 700,000 in 2010.

17 Mar 2015

Scientists use x-ray vision to probe early stages of DNA 'photocopying'

Scientists at Johns Hopkins have created a 3-D model of a complex protein machine, ORC, which helps prepare DNA to be duplicated.

16 Mar 2015

TSRI researchers create picture of whole dynein-dynactin structure

A team led by scientists at The Scripps Research Institute has determined the basic structural organization of a molecular motor that hauls cargoes and performs other critical functions within cells.

12 Mar 2015

New drug shows promise in driving insulin-producing beta cells to multiply

In a screen of more than 100,000 potential drugs, only one, harmine, drove human insulin-producing beta cells to multiply, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai, funded by JDRF and the National Institutes of Health, and published online today in Nature Medicine.

10 Mar 2015

Understanding genetic machinery that drives malignant pediatric adrenocortical tumors

In an advance that could lead to better identification of malignant pediatric adrenocortical tumors, and ultimately to better treatment, researchers have mapped the "genomic landscape" of these rare childhood tumors. Their genomic mapping has revealed unprecedented details, not only of the aberrant genetic and chromosomal changes that drive the cancer, but the sequence of those changes that trigger it.

10 Mar 2015

Pediatric Cancer Genome Project identifies genetic basis of three pediatric melanoma subtypes

The St. Jude Children's Research Hospital—Washington University Pediatric Cancer Genome Project found that melanoma in some adolescent and adult patients involves many of the same genetic alterations and would likely respond to the same therapy.

5 Mar 2015

U of T Scarborough professor develops new compound that can lead to cheaper anti-cancer drugs

A new compound developed at the University of Toronto Scarborough could play an important role in developing cheaper anti-cancer drugs.

26 Feb 2015

Cell Division News and Research

Eribulin from marine sponge inhibits replication of breast cancer cells

TAXIS Pharmaceuticals' TXA709 compound shows promise in combating antibiotic resistance

Scientists identify possible new genes that could change benign skin growths into fatal melanomas

UC Davis assistant professor wins Hartwell Foundation award to explore treatment for juvenile diabetes

Study confirms that coffee inhibits growth of tumours, reduces risk of breast cancer recurrence

Global changes in cancer cells' epigenome may determine disease progression

Myc cancer gene allows tumor cells to divide, provokes cell suicide process

New method for measuring genetic variability may help identify patients with aggressive cancers

Genetically modified Salmonella can help kill cancer cells

UC Davis researchers unravel how micro RNA could potentially lead to novel cancer therapies

Dartmouth researchers use new strategies to target drug-resistant pathogens

Mitochondrial DNA movement: an interview with Professor Jiri Neuzil, Griffith University

Duke researchers develop new model to study why some HPV infections go away and others progress

Penn researchers find evidence of new culprit in colon cancer

Scientists use x-ray vision to probe early stages of DNA 'photocopying'

TSRI researchers create picture of whole dynein-dynactin structure

New drug shows promise in driving insulin-producing beta cells to multiply

Understanding genetic machinery that drives malignant pediatric adrenocortical tumors

Pediatric Cancer Genome Project identifies genetic basis of three pediatric melanoma subtypes

U of T Scarborough professor develops new compound that can lead to cheaper anti-cancer drugs

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