Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Start-up receives NIH grant to accelerate development of contrast agent to detect liver fibrosis

Inlighta Biosciences, LLC, a start-up company led by Jenny Yang, Regents' Professor of Chemistry at Georgia State University, has been awarded a National Institute of Health grant to accelerate development of a magnetic resonance imaging contrast agent to detect liver fibrosis, formation of scar tissue in the liver caused by alcoholic and non-alcoholic fatty liver disease.

15 Oct 2020

Even mild fatty liver disease associated with higher risk of all-cause mortality

Non-alcoholic fatty liver disease, NAFLD, affects nearly one in four adults in Europe and the U.S. Earlier research has demonstrated an increased risk of death in patients with NAFLD and advanced fibrosis or cirrhosis.

12 Oct 2020

Analysis of existing comorbidities and COVID-19 mortality

As the COVID-19 pandemic continues to spread, and research related to potential risk factors for COVID-19 mortality continues, it is becoming clear that individuals with underlying comorbidities have a greater risk of death from COVID-19. The exact contribution of different comorbidities is unclear, however. Now, a new study published in the journal PLOS ONE dissects this topic and may help to quantify the risk posed by specific conditions and offer help with the prognosis.

11 Oct 2020

Certain pre-existing conditions may highly increase a patient's risk of dying from COVID-19

A large, international study of COVID-19 patients confirmed that cardiovascular disease, hypertension, diabetes, congestive heart failure, chronic kidney disease, stroke and cancer can increase a patient's risk of dying from the virus.

8 Oct 2020

Pre-existing conditions can increase patient's risk of dying from COVID-19

8 Oct 2020

Researchers create p16-Cre ERT2 -tdTomato mouse model to characterize in vivo senescent cells

Cell senescence is a state of permanent cell cycle arrest that was initially defined for cells grown in cell culture. It plays a key role in age-associated organ dysfunction and age-related diseases such as cancer, but the in vivo pathogenesis is largely unclear.

7 Oct 2020

Maternal sugary beverage intake during breastfeeding impacts cognitive development in children

A diet high in sugar during adulthood is associated with weight gain, and has also been linked to risk of type 2 diabetes, fatty liver disease, and heart disease.

6 Oct 2020

NIH awards $13.8 million to conduct studies on pre-dementia and Alzheimer's disease

Joe Verghese, M.B.B.S., M.S., , an international leader in aging and cognition research at Albert Einstein College of Medicine and Montefiore Health System, has received two grants from the National Institutes of Health totaling $13.8 million to conduct studies on pre-dementia and Alzheimer's disease.

5 Oct 2020

NIH awards grants for using bioengineered models to improve clinical trial design

Clinical Trials on a Chip researchers plan to build and test common and rare disease models to help improve the clinical trial process.

30 Sep 2020

Risk factors for mortality among hospitalized patients with COVID-19

A new study by scientists at biotechnology company Genentech, Inc., and published on the preprint server medRxiv in September 2020 attempts to identify the factors which may shape the risk for death in COVID-19 disease.

27 Sep 2020

University of Minnesota receives funding to initiate research on diabetes drug as a COVID-19 treatment

University of Minnesota Medical School researchers received funding from the Parsemus Foundation to initiate research on the widely-used diabetes medication, metformin, available globally as an inexpensive generic drug for prevention and treatment for COVID-19.

25 Sep 2020

Gruthan Bioscience to develop new class of cholesterol-lowering drugs

Gruthan Bioscience, LLC, a Medical University of South Carolina startup based in Charleston, South Carolina, received a Small Business technology Transfer (STTR) award from the National Heart, Blood and Lung Institute in August to take the next step in developing a novel class of cholesterol-lowering drugs to treat familial hypercholesterolemia.

24 Sep 2020

Owlstone Medical releases positive study results on use of breath biopsy for better liver disease diagnosis

Owlstone Medical, the global leader in Breath Biopsy for applications in early disease detection and precision medicine, today announced the results of a patient study that successfully demonstrates the use of exhaled limonene as a breath biomarker to measure liver function and stage liver disease.

From Owlstone Medical Ltd 23 Sep 2020

Research consortium receives $111 million NCI grant to prevent, treat HIV-related cancers

The widespread use of antiretroviral therapy to suppress the HIV virus has helped tens of millions of people with HIV live healthier, longer lives--but an unfortunate consequence of people living longer with HIV is an increased risk of cancer.

22 Sep 2020

Middle-aged people report more pain than older Americans, study finds

A new study finds middle-aged Americans are now reporting more pain than the elderly -- and it has to do with their level of education and that pain is rising more quickly in younger people.

22 Sep 2020

Study detects key differences in immune responses of adults and children with COVID-19

The first study comparing the immune responses of adults and children with COVID-19 has detected key differences that may contribute to understanding why children usually have milder disease than adults.

22 Sep 2020

CNIC researchers uncover a mechanism explaining how macrophages regulate obesity

Macrophages are immune system cells. They are essential in the early response to infections, and they also have a key role in the proper functioning of our tissues and the regulation of obesity.

17 Sep 2020

Study provides valuable insights on effects of APOE gene on health and disease

From Alzheimer's to obesity, life can change dramatically if you discover you have a genetic risk of disease. Now, a new study from the Australian Centre for Precision Health, University of South Australia is challenging these predispositions, showing that some of the genes traditionally labelled as 'bad' are not always what they seem.

16 Sep 2020

Researchers are testing the effectiveness of multiple treatments to prevent COVID-19

A study on the effectiveness of multiple treatments, including laboratory-made antibodies, at preventing mild COVID-19 from advancing to severe illness in the outpatient setting is underway by researchers at The University of Texas Health Science Center at Houston (UTHealth).

16 Sep 2020

Study identifies gene that could decrease chances of developing alcoholic cirrhosis

Researchers at Indiana University School of Medicine are learning more about how a person's genes play a role in the possibility they'll suffer from alcoholic cirrhosis with the discovery of a gene that could make the disease less likely.

12 Sep 2020

Liver Disease News and Research

Further Reading

Start-up receives NIH grant to accelerate development of contrast agent to detect liver fibrosis

Even mild fatty liver disease associated with higher risk of all-cause mortality

Analysis of existing comorbidities and COVID-19 mortality

Certain pre-existing conditions may highly increase a patient's risk of dying from COVID-19

Pre-existing conditions can increase patient's risk of dying from COVID-19

Researchers create p16-Cre ERT2 -tdTomato mouse model to characterize in vivo senescent cells

Maternal sugary beverage intake during breastfeeding impacts cognitive development in children

NIH awards $13.8 million to conduct studies on pre-dementia and Alzheimer's disease

NIH awards grants for using bioengineered models to improve clinical trial design

Risk factors for mortality among hospitalized patients with COVID-19

University of Minnesota receives funding to initiate research on diabetes drug as a COVID-19 treatment

Gruthan Bioscience to develop new class of cholesterol-lowering drugs

Owlstone Medical releases positive study results on use of breath biopsy for better liver disease diagnosis

Research consortium receives $111 million NCI grant to prevent, treat HIV-related cancers

Middle-aged people report more pain than older Americans, study finds

Study detects key differences in immune responses of adults and children with COVID-19

CNIC researchers uncover a mechanism explaining how macrophages regulate obesity

Study provides valuable insights on effects of APOE gene on health and disease

Researchers are testing the effectiveness of multiple treatments to prevent COVID-19

Study identifies gene that could decrease chances of developing alcoholic cirrhosis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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