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Groundbreaking technology could enhance therapeutic efficiency of nanomedicines

Researchers from the Moscow Institute of Physics and Technology and their colleagues from Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry and Prokhorov General Physics Institute of the Russian Academy of Sciences have developed a breakthrough technology to resolve a key problem that has prevented the introduction of novel drugs into clinical practice for decades.

17 Jul 2020

Anaplastic large cell lymphoma: Defense mechanism against certain drugs promotes cancer growth

A general problem encountered in cancer therapy is that many patients develop resistance to a drug over the course of treatment.

15 Jul 2020

Dual inhibitor therapy may be safer for CLL patients, Moffitt study shows

Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. One in four new leukemia cases are CLL.

14 Jul 2020

Study shows safety and effectiveness of PET radiotracer in imaging glioblastomas

A first-in-human study presented at the Society of Nuclear Medicine and Molecular Imaging 2020 Annual Meeting has demonstrated the safety, favorable pharmacokinetic and dosimetry profile of 64Cu-EBRGD, a new, relatively long-lived PET tracer, in patients with glioblastomas.

13 Jul 2020

Promising new approach uses natural killer cells to treat glioblastomas

Glioblastomas are the most common malignant brain tumors in adults. Treatment options are extremely limited and usually not effective, leading to death for most patients within 12-18 months of diagnosis.

9 Jul 2020

Mapping immune landscape of hematological malignancies may help improve cancer therapies

Activating the immune system of the body is a promising form of treatment for cancer. Researchers at the University of Helsinki and Helsinki University Hospital as well as the University of Eastern Finland mapped out the immune landscape of hematological malignancies in a dataset covering more than 10,000 patients to identify drug targets and patient groups which could potentially benefit from immunotherapies.

9 Jul 2020

Study suggests new potential strategy to fight against pancreatic cancer

A University of Michigan-led study is shedding new light on the way pancreatic cancer cells turn nearby connective tissue cells into co-conspirators in their deadly growth.

6 Jul 2020

Inflammatory changes in tumors can cause drug resistance in cancer blood vessels

Scientists at Hokkaido University and collaborators have identified how inflammatory changes in tumors caused by chemotherapy trigger blood vessel anomalies and thus drug-resistance, resulting in the poor prognosis of cancer patients.

1 Jul 2020

Researchers identify a novel mutation through whole-exome sequencing

Long QT syndrome (LQTS), caused by an ion channel-related gene mutation, is a malignant heart disease with a clinical course of a high incidence of ventricular fibrillation and sudden cardiac death in the young.

27 Jun 2020

Researchers discover key signaling pathway in the pathogenesis of Paget's disease

Researchers from the University of California, Irvine, in collaboration with their colleagues from Beijing, China, have gained new insights into the development of poorly understood malignant skin cancers collectively known as Paget's disease.

26 Jun 2020

ASCCP issues new guidelines for managing abnormal results on cervical cancer screening

Replacing guidelines for managing women with abnormal results on cervical cancer screening tests from 2012, new recommendations from ASCCP emphasize more precise management based on estimates of the patient's risk - enabling more personalized recommendations for diagnosis, treatment, and follow-up.

26 Jun 2020

Artificial neural network can provide information about lung cancer severity

Computed tomography (CT) is a major diagnostic tool for assessment of lung cancer in patients. Now NIBIB-funded researchers at Stanford University have created an artificial neural network that analyzes lung CT scans to provide information about lung cancer severity that can guide treatment options.

25 Jun 2020

Certain genes that predispose to cancer also affect the immune system, study shows

The study shows that the involvement of certain genes that predispose to cancer also affects the immune system, which could facilitate tumor growth.

25 Jun 2020

Standard smartphone technology can be adapted to image skin lesions

An article published in the Journal of Biomedical Optics (JBO), "Point-of-care, multispectral, smartphone-based dermascopes for dermal lesion screening and erythema monitoring," shows that standard smartphone technology can be adapted to image skin lesions, providing a low-cost, accessible medical diagnostic tool for skin cancer.

23 Jun 2020

Producing CAR T cell therapy at a lower cost

Chimeric antigen receptor (CAR) T cell therapy is a new and in some cases highly effective form of immunotherapy to treat certain types of cancer of the blood and lymph system.

23 Jun 2020

Collaboration between human and artificial intelligence has huge potential in medicine

Artificial Intelligence (AI) is increasingly being used in medicine to support human expertise. However, the potential of these applications and the risks inherent in the interaction between human and artificial intelligence has not yet been thoroughly researched.

23 Jun 2020

Innovative use of focused ultrasound shows promise against glioblastoma

An innovative use of focused ultrasound being pioneered at the University of Virginia School of Medicine is showing promise against glioblastoma, the deadliest brain tumor, and could prove useful against other difficult-to-treat cancers.

22 Jun 2020

Near-infrared photoimmunotherapy could improve treatment for malignant lung cancer

Treating a rare type of malignant lung cancer could improve, thanks to near-infrared irradiation and a cancer-targeting compound. Nagoya University oncologist Kazuhide Sato and colleagues tested the treatment and published their findings in the journal Cells.

20 Jun 2020

Developing betatron based medical complexes to reduce the chance of cancer recurrence

Tomsk Polytechnic University, JSC Academician M.F. Reshetnev Information Satellite Systems and the Polyus Research and Development Center will create the betatron based medical complexes, reducing the chance of cancer recurrence.

19 Jun 2020

New technology detects breast cancer using tears

Kobe University and System Instruments Co., Ltd. researchers have developed TearExo; new technology to detect breast cancer using the exosomes found in tears as biomarkers. Exosomes are a subtype of extracellular vesicles.

19 Jun 2020

Malignant News and Research

Groundbreaking technology could enhance therapeutic efficiency of nanomedicines

Anaplastic large cell lymphoma: Defense mechanism against certain drugs promotes cancer growth

Dual inhibitor therapy may be safer for CLL patients, Moffitt study shows

Study shows safety and effectiveness of PET radiotracer in imaging glioblastomas

Promising new approach uses natural killer cells to treat glioblastomas

Mapping immune landscape of hematological malignancies may help improve cancer therapies

Study suggests new potential strategy to fight against pancreatic cancer

Inflammatory changes in tumors can cause drug resistance in cancer blood vessels

Researchers identify a novel mutation through whole-exome sequencing

Researchers discover key signaling pathway in the pathogenesis of Paget's disease

ASCCP issues new guidelines for managing abnormal results on cervical cancer screening

Artificial neural network can provide information about lung cancer severity

Certain genes that predispose to cancer also affect the immune system, study shows

Standard smartphone technology can be adapted to image skin lesions

Producing CAR T cell therapy at a lower cost

Collaboration between human and artificial intelligence has huge potential in medicine

Innovative use of focused ultrasound shows promise against glioblastoma

Near-infrared photoimmunotherapy could improve treatment for malignant lung cancer

Developing betatron based medical complexes to reduce the chance of cancer recurrence

New technology detects breast cancer using tears

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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