Malignant News and Research

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Developing an international consortium to improve clinical decision-making in Hodgkin lymphoma

A harmonization of 'big data' in examining long-term outcomes with contemporary treatment for pediatric and adult Hodgkin lymphoma patients is yielding a new approach to inform future clinical trial design and enhance clinical decision-making.

30 May 2020

Survival probabilities in esophageal surgery increase with volume of hospital services

In complex surgery, is there a correlation between the volume of services provided per hospital and the quality of treatment results? This is the question addressed in eight commissions on minimum volumes that the Federal Joint Committee (G-BA) awarded to the Institute for Quality and Efficiency in Health Care.

29 May 2020

Inhibiting tumor signals can suppress the spread of cancer

For most people who die of cancer, the spread of the initial tumor is to blame. "Metastasis is what kills most cancer patients," says Serge Fuchs, a professor in Penn's School of Veterinary Medicine.

28 May 2020

Characterizing immune cells in malignant brain tumors

It is not always possible to completely remove malignant brain tumors by surgery so that further treatment is necessary.

28 May 2020

A new approach to predict the evolutionary mechanisms of melanoma

Melanoma is a malignant tumour resulting from the transformation of melanocytes, the cells in the skin that undertake to synthesise melanin, a complex polymer which protects us from the negative effects of solar radiation.

27 May 2020

Lymph node and distant metastases develop through different evolutionary mechanisms, study shows

The evolutionary processes underlying metastasis-the development of secondary malignant growths away from the primary tumor site-in human patients are still incompletely understood.

26 May 2020

New technique offers high-resolution 3D view inside tumors

Malignant tumors consume nutrients and oxygen faster than healthy cells. To do so, they recruit blood vessels in their environment. Depending on tumor type and genetic profile, there are differences on how tumors look internally.

26 May 2020

Cell-culture based in vitro test systems for antitumor drug screening

As we know, a malignant tumor is a complex system of mutated cells which constantly interacts with and involves healthy cells in the body.

21 May 2020

Scientists use new model to develop cancer stem cells

Liver cancer is one of the deadliest cancers. It is insidious and does not present symptoms until it has progressed considerably, at which point, treatment options are limited and chances of survival are low. The most common type of liver cancer is hepatocellular carcinoma (HCC).

21 May 2020

Durvalumab plus chemotherapy improved overall survival rate for mesothelioma patients

PrECOG, LLC is reporting clinical efficacy and biomarker analyses from its single-arm phase two study PrE0505 for the initial treatment of patients with malignant pleural mesothelioma.

20 May 2020

Sleep apnea may increase the risk of severe COVID-19, say researchers

An analysis conducted by researchers at the University of Turku and Turku University Hospital in Finland has suggested that obstructive sleep apnea (OSA) may be a risk factor for severe coronavirus disease 2019 (COVID-2019).

19 May 2020

Study shows how normal RAS interacts with mutated RAS in living cells

Many cancer medications fail to effectively target the most commonly mutated cancer genes in humans, called RAS.

19 May 2020

Study shows how cancer protein changes may accelerate tumorigenesis and metastasis

Understanding the genetic mutations and protein changes that take place in the progression of cancer is key to its treatment. Mutations in the gene TP53 and concomitant mutant p53 proteins in cancer cells have become notorious over the course of multiple studies of several different types of cancers.

18 May 2020

First detailed study of the epigenetic landscape of human tumor organoids

The researcher Manel Esteller performs the first massive epigenetic characterization in organoids or 3D cancer cultures and makes the data available to the research community to facilitate new findings on tumor development and progression.

15 May 2020

Researchers find higher prevalence of benign gynecologic lesions than previously reported

Over the last decade researchers have become concerned about a possible link between a benign gynecologic lesion called endosalpingiosis (ES) and ovarian cancer.

13 May 2020

First detailed study of the epigenetic landscape of human tumor organoids

Frequently, promising cancer therapies fail when applied to patients in the real clinical setting. This occurs despite many of these new treatments demonstrating promising results at the preclinical stage in the lab.

13 May 2020

Study provides further insights into the relationship between smoking and COVID-19

A Canadian study available on the preprint server medRxiv* shows that current smokers are slightly more likely than never smokers to test positive for coronavirus disease (COVID-19), but cautions about the possibility of reverse causality where smokers actually quit to avoid the disease.

12 May 2020

Malignant News and Research

Developing an international consortium to improve clinical decision-making in Hodgkin lymphoma

Survival probabilities in esophageal surgery increase with volume of hospital services

Inhibiting tumor signals can suppress the spread of cancer

Characterizing immune cells in malignant brain tumors

A new approach to predict the evolutionary mechanisms of melanoma

Lymph node and distant metastases develop through different evolutionary mechanisms, study shows

New technique offers high-resolution 3D view inside tumors

Cell-culture based in vitro test systems for antitumor drug screening

Scientists use new model to develop cancer stem cells

Durvalumab plus chemotherapy improved overall survival rate for mesothelioma patients

Sleep apnea may increase the risk of severe COVID-19, say researchers

Study shows how normal RAS interacts with mutated RAS in living cells

Study shows how cancer protein changes may accelerate tumorigenesis and metastasis

First detailed study of the epigenetic landscape of human tumor organoids

Researchers find higher prevalence of benign gynecologic lesions than previously reported

First detailed study of the epigenetic landscape of human tumor organoids

Study provides further insights into the relationship between smoking and COVID-19

Novel radiotracer is an effective option for staging of prostate cancer

Common allergy medicine may improve survival in patients with malignant melanoma

Breakthrough study could revolutionize cancer treatment

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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