Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

New method to control inflammatory response induced by COVID-19

Severe COVID-19 illness can result in excessive inflammation throughout the body, including the lungs, heart and brain. University of Minnesota Twin Cities student Molly Gilligan recently published an article in the journal Cancer & Metastasis Reviews that studied the human body's robust inflammatory response to the SARS-CoV-2 virus, which is now recognized as a hallmark symptom.

13 May 2020

New review outlines potential approaches for treating cold tumors

Announcing a new article publication for BIO Integration journal. In this review article the authors Jing Liu, Mengze Xu and Zhen Yuan from University of Macau, Macau SAR, China consider immunotherapy for the treatment of tumors.

13 May 2020

Newly launched clinical trial can help treat COVID-19 patients

Research by University of Iowa virologist Wendy Maury, PhD, has helped facilitate the launch of a new clinical trial in the United Kingdom of a drug that might help treat patients with COVID-19.

30 Apr 2020

Revolutionary imaging technique may help diagnose and treat cancer

A first-of-its-kind nanoparticle-based in vivo imaging technique that may one day be used to help diagnose and even treat cancer has been developed by researchers collaborating from Michigan State, Johns Hopkins and Stanford universities.

30 Apr 2020

CNIC researchers develop mouse model to examine the mechanical function of proteins

The Molecular Mechanics of the Cardiovascular System group at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), led by Jorge Alegre Cebollada, in partnership with an international scientific team, has generated the first experimental mouse model that allows direct analysis of the mechanical function of proteins in living organisms.

28 Apr 2020

Patients with aggressive form of skin cancer can benefit from new type of immunotherapy

In what is believed to be a first-of-its-kind study to evaluate the safety of a type of immunotherapy before surgery in patients with an aggressive form of skin cancer, researchers report that the treatment eliminated pathologic evidence of cancer in nearly half of the study participants undergoing surgery.

27 Apr 2020

Therapeutic antibody successfully prevents metastases in mice with breast or lung cancer

A receptor in the cell layer that lines the blood vessels from the inside stimulates both the formation of new blood vessels in tumors and metastasis.

24 Apr 2020

Combinations of PAC and WFA are highly synergistic against proliferation of non-small cell lung cancer

Oncotarget Volume 11 Issue 16 showed that the sensitivity of H1299 and A549 cells to concomitant treatment with PAC and WFA was greater than that of either PAC or WFA alone.

23 Apr 2020

Scientists find gene signature for poor response to standard therapy in rare uterine cancer

Women who don't survive a rare and aggressive uterine cancer called uterine serous carcinoma, have high expression of a group of 73 genes, a score scientists say can help identify these women and improve their outcome.

22 Apr 2020

Chronic stress can influence the efficacy of radiation therapy, study suggests

Radiation is one of the oldest and most common therapies for cancer, and typically is delivered locally, or to specific targeted sites in the body.

15 Apr 2020

Molecular pathway responsible for TNBC's progression and spread identified

Immunotherapies have revolutionized treatment for people with a variety of cancers. But when given to those with triple-negative breast cancer, a particularly aggressive form of the disease, less than 20% respond.

13 Apr 2020

Missing BAP1 gene renders immunotherapies ineffectual in uveal melanomas

New study from researchers in Finland and the United Kingdom reveals that tumors lacking a protein called BAP1 have an ineffective immune reaction against cancer, thus rendering immunotherapies ineffectual, particularly in uveal melanomas.

9 Apr 2020

Advance in understanding actin sheds light on cell function

Scientists have discovered more about actin, a chemical modification on one of the most abundant and important proteins.

8 Apr 2020

Novel research explores interaction between engineered gene circuits and biological host cells

Recent discoveries by two research teams in the Ira A. Fulton Schools of Engineering at Arizona State University are advancing the field of synthetic biology.

7 Apr 2020

Researchers identify new therapeutic strategies against cancer

New findings open up to new therapeutic strategies against cancer. IGC researchers identify signals emitted by the tumor environment, which controls the migrating capacity of cancer cells.

1 Apr 2020

Highly focused radiation may slow disease progression in men with oligometastatic prostate cancer

Highly focused, intense doses of radiation called stereotactic ablative radiation (SABR) may slow progression of disease in a subset of men with hormone-sensitive prostate cancers that have spread to a few separate sites in the body, according to results of a phase II clinical trial of the therapy.

26 Mar 2020

Intense and targeted radiotherapy could slow progression of certain prostate cancers

Targeted and strong doses of stereotactic ablative radiation (SABR) radiotherapy could slow progression in prostate cancer.

26 Mar 2020

Changes in surface sugarlike molecules help cancer cells to spread

Changes in a specific type of sugarlike molecule, or glycan, on the surface of cancer cells help them to spread into other tissues, according to researchers at the University of California, Davis. Published March 23 in Proceedings of the National Academy of Sciences, the work could lead to diagnostic tests and new therapies to slow or stop the spread of cancers.

25 Mar 2020

NYUAD researchers develop new microfluidic platform to perform cancer liquid biopsies

Cancer is one of the leading causes of death worldwide, and has been found to have a significantly higher rate of survival when diagnosed at early stages, before metastasis.

23 Mar 2020

Study provides better understanding of how dangerous cancer metastases arise

In order to colonize other organs and grow into metastases, tumor cells that detach from the parent tumor need to manipulate their new microenvironment and create a 'metastatic niche'.