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Insulin and nutrition keep blood stem cells from differentiating into mature blood cells

UCLA stem cell researchers have shown that insulin and nutrition keep blood stem cells from differentiating into mature blood cells in Drosophila, the common fruit fly, a finding that has implications for studying inflammatory response and blood development in response to dietary changes in humans.

12 Mar 2012

Scientists demonstrate how immortal flatworm overcomes aging process

Researchers from The University of Nottingham have demonstrated how a species of flatworm overcomes the ageing process to be potentially immortal.

28 Feb 2012

'Good-times' pumps warn cells of approaching starvation

Sugar, cholesterol, phosphates, zinc - a healthy body is amazingly good at keeping such vital nutrients at appropriate levels within its cells. From an engineering point of view, one all-purpose model of pump on the surface of a cell should suffice to keep these levels constant: When the concentration of a nutrient, say, sugar, drops inside the cell, the pump mechanism could simply go into higher gear until the sugar levels are back to normal.

23 Feb 2012

Candida albicans can sense immune status of host cells and evade them

Glen Palmer, PhD, Assistant Professor of Microbiology, Immunology & Parasitology at LSU Health Sciences Center New Orleans, was part of an international research team led by Luigina Romani, MD, at the University of Perugia, that discovered opportunistic fungi like Candida albicans can sense the immune status of host cells and adapt, evading immune system defenses.

23 Feb 2012

Researchers discover mechanism of thermostat protein

Johns Hopkins and National Taiwan University researchers have discovered more details about how an energy sensing "thermostat" protein determines whether cells will store or use their energy reserves.

22 Feb 2012

Evolutionary biologist receives LRI grant for lupus research

Evolutionary biologist Harmit Singh Malik, Ph.D., of Fred Hutchinson Cancer Research Center, has received a $300,000 grant from the Lupus Research Institute to study the potential role of "genetic conflicts" in the development of lupus, an autoimmune disease.

18 Feb 2012

BGI and VIB's genomics meeting to take place on Feb. 15

Both organizations are already collaborating on several projects, including the mapping of the genomes of more than 1,000 species of gut bacteria, compiled from 577 billion base pairs of sequence data. The leading scientific journal Science selected this work as one of the scientific breakthroughs of 2011. Large-scale genome sequencing is becoming ever more important in life sciences, healthcare and agricultural research.

9 Feb 2012

Fasting and chemotherapy drugs more effectively treat cancers

Man may not live by bread alone, but cancer in animals appears less resilient, according to a study that found chemotherapy drugs work better when combined with cycles of short, severe fasting.

9 Feb 2012

New technique to overcome genetic oddity of P. falciparum

The parasite that causes malaria is a genetic outlier, which has prevented scientists from discovering the functions of most of its genes. Researchers at National Jewish Health and Yale University School of Medicine have devised a technique to overcome the genetic oddity of Plasmodium falciparum, the major cause of human malaria.

27 Jan 2012

WSU professors receive NSF grant to develop math model of liver metabolism

Predicting problems in one of the body's most complex organs soon may become easier because of work being done by Wayne State University researchers.

20 Jan 2012

Researchers develop simple process for synthesis of artemisinin

The most effective anti-malaria drug can now be produced inexpensively and in large quantities. This means that it will be possible to provide medication for the 225 million malaria patients in developing countries at an affordable price. Researchers at the Max Planck Institute of Colloids and Interfaces in Potsdam and the Freie Universit-t Berlin have developed a very simple process for the synthesis of artemisinin, the active ingredient that pharmaceutical companies could only obtain from plants up to now.

18 Jan 2012

UI chemists debunk misconception about amphotericin

With one simple experiment, University of Illinois chemists have debunked a widely held misconception about an often-prescribed drug.

17 Jan 2012

Damon Runyon Cancer Research Foundation names 18 new Fellows

The Damon Runyon Cancer Research Foundation, a non-profit organization focused on supporting innovative early career researchers, named 18 new Damon Runyon Fellows at its fall Fellowship Award Committee review.

11 Jan 2012

Researchers identify potential target for schistosomiasis vaccine

In the complicated life cycle of ancient flatworms that cause schistosomiasis, Case Western Reserve University researchers have identified a gene activator crucial to development of the parasites within humans - a potential target for a vaccine.

6 Jan 2012

Lithocholic acid can kill several types of cancer cells

Lithocholic acid (LCA), naturally produced in the liver during digestion, has been seriously underestimated. A study published in the journal Oncotarget shows that LCA can kill several types of cancer cells, such as those found in some brain tumors and breast cancer.

5 Jan 2012

Scientists discover how DNA mismatch repair proteins work

In eukaryotes - the group of organisms that include humans - a key to survival is the ability of certain proteins to quickly and accurately repair genetic errors that occur when DNA is replicated to make new cells.

23 Dec 2011

Researchers develop CAD-type tools to engineer RNA control systems

The computer assisted design (CAD) tools that made it possible to fabricate integrated circuits with millions of transistors may soon be coming to the biological sciences. Researchers at the U.S. Department of Energy (DOE)'s Joint BioEnergy Institute (JBEI) have developed CAD-type models and simulations for RNA molecules that make it possible to engineer biological components or "RNA devices" for controlling genetic expression in microbes.

23 Dec 2011

Six UNC faculty members named AAAC fellow

Six University of North Carolina at Chapel Hill faculty members have been named fellows of the American Association for the Advancement of Science.

16 Dec 2011

Combination of two techniques promises to improve effectiveness of experimental gene therapies

yeast or phages act not only to tag and target but also to exchange specific genes in DNA A combination of two techniques promises to improve the efficiency and effectiveness of experimental gene therapies, while also reducing potential side effects says a new research report published in the December 2011 issue of the FASEB Journal.

1 Dec 2011