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AstraZeneca announces encouraging results from olaparib phase II study in serous ovarian cancer

AstraZeneca announced today encouraging results from a phase II study in patients with platinum-sensitive relapsed serous ovarian cancer (SOC) who had received maintenance treatment with the investigational drug olaparib, after the completion of chemotherapy.

19 May 2011

NEW Lifestyle on-line teaching modules for medical students

Obesity is an epidemic and when paired with physical inactivity it represents the second leading cause of preventable death nationally from cancer, cardiovascular diseases and diabetes. But in medical school, there is a training gap when it comes to teaching future doctors about obesity and related health problems.

19 May 2011

Fragile X syndrome may be treatable

Advancements over the last 10 years in understanding intellectual disability (ID, formerly mental retardation), have led to the once-unimaginable possibility that ID may be treatable, a review of more than 100 studies on the topic has concluded. It appears in ACS Chemical Neuroscience.

18 May 2011

Neurochemical basis for sleep deprivation's effects on memory

From high-school students to surgeons, anyone who has pulled an all-nighter knows there is a price to be paid the next day: trouble focusing, a fuzzy memory and other cognitive impairments. Now, researchers at Penn have found the part of the brain and the neurochemical basis for sleep deprivation's effects on memory.

18 May 2011

Treatment of chronic low back pain can reverse abnormal brain activity and function

It likely comes as no surprise that low back pain is the most common form of chronic pain among adults. Lesser known is the fact that those withchronic pain also experience cognitive impairments and reduced gray matter in parts of the brain associated with pain processing and the emotional components of pain, like depression and anxiety.

18 May 2011

Positive results from Astellas Pharma's mirabegron phase III trial in overactive bladder

Astellas Pharma US, Inc., U.S. subsidiary of Astellas Pharma Inc., today announced the results of a pivotal phase III clinical trial for mirabegron, the first of a new class of compounds under development for the treatment of overactive bladder (OAB), which show mirabegron significantly improves key OAB symptoms – urinary incontinence and frequency of micturition compared with placebo.

18 May 2011

Early exposure to social deprivation and neglect linked to prematurely shortened telomeres in children

Studies in institutionalized Romanian children have found that the length of time spent in conditions of social deprivation and neglect correlates with lower IQ and behavioral problems. A new study, led by researchers at Children's Hospital Boston and Tulane University, shows that early adversity even affects children's chromosomes – prematurely shortening the chromosome tips, known as telomeres, and hastening how quickly their cells "age."

17 May 2011

The biophysics of snakebites

For years Professor Leo von Hemmen, a biophysicist at the TU Muenchen, and Professor Bruce Young, a biologist at the University of Massachusetts Lowell, have been researching the sense of hearing in snakes.

17 May 2011

SYMBICORT long-term comparative study data in African American asthma patients presented at ATS 2011

AstraZeneca today announced results from a long-term study comparing SYMBICORT Inhalation Aerosol 160/4.5 mcg with budesonide pressurized metered-dose inhaler 160 mcg in self-reported African American patients with moderate to severe persistent asthma.

17 May 2011

Merck acquires Inspire Pharmaceuticals

Merck, known as MSD outside the United States and Canada, announced today that it is has completed its acquisition of Inspire Pharmaceuticals, Inc., a specialty pharmaceutical company focused on developing and commercializing ophthalmic products, for $5.00 per share in cash.

17 May 2011

InVivo Therapeutics reports net loss of $1,278,000 for first quarter 2011

InVivo Therapeutics, a medical device company focused on the development of groundbreaking technologies for the treatment of spinal cord injuries, today reported financial results for the first quarter 2011.

16 May 2011

Study reveals role of KLF14 regulatory gene in type 2 diabetes

A team of researchers, led by King's College London and the University of Oxford, have found that a gene linked to type 2 diabetes and cholesterol levels is in fact a 'master regulator' gene, which controls the behaviour of other genes found within fat in the body.

16 May 2011

Study reveals crucial role of histone deacetylases in type 2 diabetes

A uniquely collaborative study by researchers at the Salk Institute for Biological Studies uncovered a novel mechanism that turns up glucose production in the liver when blood sugar levels drop, pointing towards a new class of drugs for the treatment of metabolic disease.

16 May 2011

Scientists discover new class of compounds that selectively block 'serine hydrolases'

Scientists from The Scripps Research Institute have identified a class of compounds that could be a boon to basic research and drug discovery.

16 May 2011

Otsuka Pharmaceutical reports OPC-34712 Phase 2 trial results in major depressive disorder

Otsuka Pharmaceutical Co., Ltd. (OPC) and Otsuka Pharmaceutical Development & Commercialization, Inc. (OPDC) today announced results from a Phase 2 clinical trial of OPC-34712, a novel D2 dopamine partial agonist investigational product.

16 May 2011

Nine nurses earn UC Irvine recognition for patient care, education and guidance, teamwork

Each year during National Nurses Week, UC Irvine Medical Center honors nurses who demonstrate excellence in patient care, education and guidance, mentorship, and teamwork.

13 May 2011

Midbrain habenula region plays a key role in nicotine dependence

A person's vulnerability to nicotine addiction appears to have a genetic basis, at least in part. A region in the midbrain called the habenula plays a key role in this process, as Dr. In-s Iba-ez-Tallon and her team from the Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch, Germany, have now shown.

13 May 2011

Study offers hints to why Parkinson's so selectively harms dopamine-producing cells

New data offer hints to why Parkinson's disease so selectively harms brain cells that produce the chemical dopamine, say researchers at Washington University School of Medicine in St. Louis.

13 May 2011

German doctors among first to treat ischemic stroke patients with new blood clot retrieval device

Doctors in Germany are among the first to treat ischemic stroke patients outside the United States with the REVIVE SE, a new self-expanding blood clot retrieval and removal device designed to remove blood clots and restore blood flow to the brain in patients having a stroke.

12 May 2011

Swedish adds new virtual reality training simulator to help surgeons practice on robotic-assisted system

As one of the first medical centers in the Northwest to perform robotic-assisted surgery, Swedish is home to the fastest growing, most comprehensive and experienced robotic-assisted surgical program in the region. Swedish established the multidisciplinary, robotic-assisted surgical program in 2005 and has since performed more than 3,400 robotic-assisted surgeries -- more than any other program in the region.

12 May 2011

Neuroscience News and Research

AstraZeneca announces encouraging results from olaparib phase II study in serous ovarian cancer

NEW Lifestyle on-line teaching modules for medical students

Fragile X syndrome may be treatable

Neurochemical basis for sleep deprivation's effects on memory

Treatment of chronic low back pain can reverse abnormal brain activity and function

Positive results from Astellas Pharma's mirabegron phase III trial in overactive bladder

Early exposure to social deprivation and neglect linked to prematurely shortened telomeres in children

The biophysics of snakebites

SYMBICORT long-term comparative study data in African American asthma patients presented at ATS 2011

Merck acquires Inspire Pharmaceuticals

InVivo Therapeutics reports net loss of $1,278,000 for first quarter 2011

Study reveals role of KLF14 regulatory gene in type 2 diabetes

Study reveals crucial role of histone deacetylases in type 2 diabetes

Scientists discover new class of compounds that selectively block 'serine hydrolases'

Otsuka Pharmaceutical reports OPC-34712 Phase 2 trial results in major depressive disorder

Nine nurses earn UC Irvine recognition for patient care, education and guidance, teamwork

Midbrain habenula region plays a key role in nicotine dependence

Study offers hints to why Parkinson's so selectively harms dopamine-producing cells

German doctors among first to treat ischemic stroke patients with new blood clot retrieval device

Swedish adds new virtual reality training simulator to help surgeons practice on robotic-assisted system

Event guide: 2nd Neuroscience Innovation Partnering & Licensing Summit eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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