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Study: Targeted therapy prolongs survival in patients with advanced bladder cancer

In a new study led by researchers at Yale Cancer Center, the drug enfortumab vedotin (EV) significantly prolonged survival as compared with standard chemotherapy in patients with locally advanced or metastatic urothelial carcinoma or bladder cancer, who had previously received platinum-based treatment and a PD-1–PD-L1 inhibitor.

15 Feb 2021

Study suggests a new way to personalize anti-CTLA-4 therapy for cancers

A Ludwig Cancer Research study has identified a novel mechanism by which a type of cancer immunotherapy known as CTLA-4 blockade can disable suppressive immune cells to aid the destruction of certain tumors.

15 Feb 2021

Existing heart failure drug may be effective in treating postural orthostatic tachycardia syndrome

In a new study out of University of California San Diego School of Medicine, researchers found a drug used for heart failure improves symptoms associated with postural orthostatic tachycardia syndrome, otherwise known as POTS.

15 Feb 2021

Researchers observe rapid increase of SARS-CoV-2 antibodies in plasma over pandemic's course

Researchers found that neutralizing antibodies against SARS-CoV-2 can increase over time. They observed that samples taken from convalescent plasma in September 2020 would likely have high enough values by July 2021 to protect immunodeficient patients who receive intravenous immunoglobulins as part of their treatment.

15 Feb 2021

SARS-CoV-2 South Africa and Brazil variants show resistance to therapeutic antibodies

Scientists from Germany have determined the efficacy of currently used therapeutics in treating newer variants of SARS-CoV-2, including the UK, South Africa, and Brazil variants. Their findings reveal that both B.1.351 and B.1.1.248 variants are able to escape humoral immune responses induced by therapeutic antibodies, vaccinations, or natural SARS-CoV-2 infection.

15 Feb 2021

Immunosuppressive therapies may be linked to severe COVID-19 in those with multiple sclerosis

A new study examines the associations between immunosuppressive disease-modifying therapies (DMTs) used in MS with adverse outcomes in an international cohort of patients with MS COVID-19.

15 Feb 2021

Immunomodulatory drugs improve the success rate of cancer therapies

Immunomodulatory drugs, including the Contergan derivatives lenalidomide and pomalidomide, have significantly improved the therapy of hematologic malignancies such as multiple myeloma.

15 Feb 2021

Liquid biopsy can help gauge the effectiveness of therapy for colorectal cancer

A new study from Washington University School of Medicine in St. Louis demonstrates that a liquid biopsy examining blood or urine can help gauge the effectiveness of therapy for colorectal cancer that has just begun to spread beyond the original tumor.

14 Feb 2021

New tool enables study of SARS-CoV-2 mutant spectrum by ultrasequencing

SARS-CoV-2 genome is three times larger than influenza genome. Both consist of NRA molecules that mutate when replicate.

13 Feb 2021

Study characterizes cisplatin-induced hearing loss in pediatric cancer patients

Cisplatin is one of the most effective chemotherapy agents, used in just under half of pediatric cancer cases.

13 Feb 2021

Scientists characterize genomic profile of 84 pediatric therapy-related myeloid neoplasms

Children treated for cancer with approaches such as chemotherapy can develop therapy-related myeloid neoplasms (a second type of cancer) with a dismal prognosis.

13 Feb 2021

Revolutionary drug combination shows potential for treatment of fatal childhood cancer

Every year around 20 Australian children die from the incurable brain tumor, Diffuse Intrinsic Pontine Glioma (DIPG). The average age of diagnosis for DIPG is just seven years.

13 Feb 2021

Lund researchers discover how E. coli bacteria target and degrade MYC oncogene

Scientists at Lund University have discovered how E. coli bacteria target and degrade the well-known oncogene MYC, which is involved in many forms of cancer.

13 Feb 2021

FDA approves drug to reduce frequency of chemotherapy-induced bone marrow suppression

Today, the U.S. Food and Drug Administration approved Cosela (trilaciclib) as the first therapy in its class to reduce the frequency of chemotherapy-induced bone marrow suppression in adults receiving certain types of chemotherapy for extensive-stage (when the cancer has spread beyond the lungs) small cell lung cancer.

13 Feb 2021

A novel approach to suppress the growth of glioblastoma cells

Inhibiting a key enzyme that controls a large network of proteins important in cell division and growth paves the way for a new class of drugs that could stop glioblastoma, a deadly brain cancer, from growing.

12 Feb 2021

AI-assisted video analysis can help doctors to diagnose Parkinson’s disease at an early stage

Scientists from Skoltech and A.I. Burnazyan Federal Medical and Biophysical Center have designed and developed a second opinion system, based on AI-assisted video analysis, which can help medical professionals to objectively assess patients with Parkinson’s disease (PD) even at an early stage.

12 Feb 2021

Disrupting cancer cell cycle with two commercially available inhibitors causes tumor cell death

With two commercially available inhibitors, the cell cycle of the cancer cells in the childhood tumor neuroblastoma can be disrupted at a key point causing tumor cell death.

12 Feb 2021

Study reveals detailed map of glioblastoma in genetic, molecular detail

Glioblastoma is among the most aggressive and devastating of cancers. While rare compared with other cancers, it's the most common type of brain cancer.

12 Feb 2021

Study: Marching bands need access to athletic trainers just as players do

Nearly every fall, as football teams return to the field, tragic stories of players falling ill and even dying of heat trauma make the headlines. What many don't consider is that marching band members -- who don heavy uniforms and perform in the same sweltering temperatures -- may also be at risk.

12 Feb 2021

Implant improves quality of life in patients with bilateral vestibular hypofunction

Getting around without the need to concentrate on every step is something most of us can take for granted because our inner ears drive reflexes that make maintaining balance automatic.

12 Feb 2021

Therapy News and Research

Study: Targeted therapy prolongs survival in patients with advanced bladder cancer

Study suggests a new way to personalize anti-CTLA-4 therapy for cancers

Existing heart failure drug may be effective in treating postural orthostatic tachycardia syndrome

Researchers observe rapid increase of SARS-CoV-2 antibodies in plasma over pandemic's course

SARS-CoV-2 South Africa and Brazil variants show resistance to therapeutic antibodies

Immunosuppressive therapies may be linked to severe COVID-19 in those with multiple sclerosis

Immunomodulatory drugs improve the success rate of cancer therapies

Liquid biopsy can help gauge the effectiveness of therapy for colorectal cancer

New tool enables study of SARS-CoV-2 mutant spectrum by ultrasequencing

Study characterizes cisplatin-induced hearing loss in pediatric cancer patients

Scientists characterize genomic profile of 84 pediatric therapy-related myeloid neoplasms

Revolutionary drug combination shows potential for treatment of fatal childhood cancer

Lund researchers discover how E. coli bacteria target and degrade MYC oncogene

FDA approves drug to reduce frequency of chemotherapy-induced bone marrow suppression

A novel approach to suppress the growth of glioblastoma cells

AI-assisted video analysis can help doctors to diagnose Parkinson’s disease at an early stage

Disrupting cancer cell cycle with two commercially available inhibitors causes tumor cell death

Study reveals detailed map of glioblastoma in genetic, molecular detail

Study: Marching bands need access to athletic trainers just as players do

Implant improves quality of life in patients with bilateral vestibular hypofunction

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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