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Researchers discover important drug target for preventing blood cancer

An international coalition of biomedical researchers co-led by Alexander Bick, MD, PhD, at Vanderbilt University Medical Center has determined a new way to measure the growth rate of precancerous clones of blood stem cells that one day could help doctors lower their patients' risk of blood cancer.

12 Apr 2023

Study provides direct evidence of adaptive evolution in the skin microbiome

Human skin is home to millions of microbes. One of these microbes, Staphylococcus aureus, is an opportunistic pathogen that can invade patches of skin affected by eczema, also known as atopic dermatitis.

12 Apr 2023

New potential therapeutic developed for diffuse intrinsic pontine glioma using ASO technology

Diffuse intrinsic pontine glioma (DIPG) is a lethal pediatric brain cancer that often kills within a year of diagnosis. Surgery is almost impossible because of the tumors' location.

12 Apr 2023

Cedars-Sinai Cancer collaborates on a streamlined clinical trial design in Pragmatica-Lung Study

Investigators from Cedars-Sinai Cancer are collaborating on a streamlined clinical trial design in a study called Pragmatica-Lung.

12 Apr 2023

Researchers use a quick, portable process to produce promising virus-fighting protein

A multidisciplinary research team has produced a promising virus-fighting protein using a quick, portable process that could be easily deployed at the source of a future virus outbreak.

12 Apr 2023

Pragmatica-Lung Study aims to increase accessibility to cancer clinical trials

The National Cancer Institute, part of the National Institutes of Health (NIH), has helped launch a phase 3 randomized clinical trial (NCT05633602) of a two-drug combination to treat patients with advanced non-small cell lung cancer (NSCLC).

12 Apr 2023

Unexpected discovery could inspire new strategies for preventing liver disease and cancer

Liver cancer is the third leading cause of cancer death and the sixth most common cancer type worldwide.

12 Apr 2023

Acylceramides and protein-bound ceramides are vital for the formation of oral barrier in mice

Acylceramides and protein-bound ceramides are vital for the formation of the oral barrier in mice, similar to their role in skin, protecting from infection.

12 Apr 2023

Researchers conduct experiments comparing de novo proteins with computer-generated proteins

Proteins are components of every cell. How they have changed in the course of evolution for the purpose of taking on new functions in the body, has long been a subject of research.

12 Apr 2023

The identification of vaccinee-derived antibodies with broad-spectrum Omicron neutralization activity

Reported the identification of a panel of vaccinee-derived antibodies with broad-spectrum neutralization activity.

12 Apr 2023

New organoid platform could make vaccine screening quicker and greatly reduce animal testing

Developing and testing new treatments or vaccines for humans almost always requires animal trials, but these experiments can sometimes take years to complete and can raise ethical concerns about the animals' treatment.

12 Apr 2023

Optimized genome-editing method opens the door to more effective treatment of genetic diseases

CRISPR-Cas9 is widely used to edit the genome by studying genes of interest and modifying disease-associated genes.

11 Apr 2023

Radioimmunotherapy cures human non-Hodgkin lymphoma in animal model

A new nuclear medicine therapy can cure human non-Hodgkin lymphoma in an animal model, according to research published in the April issue of The Journal of Nuclear Medicine.

11 Apr 2023

Bioprinting combined with AI allows to obtain high-quality homogenized in vitro models

In the process of organoid manufacturing, bioprinting technology can not only facilitate the creation and maintenance of complex biological 3D shapes and structures, but also allow for standardization and quality control during production.

11 Apr 2023

Cornell receives $9.5 million NIH grant for chronic fatigue research

A Cornell multidisciplinary research center that studies chronic fatigue syndrome has received a five-year, $9.5 million grant from the National Institutes of Health's National Institute of Allergy and Infectious Disease – funding that will enable experts from disparate fields to work together on the mysterious and debilitating condition.

11 Apr 2023

Exploring the tantalizing questions about sleep

Sleep is one of the most essential human activities - so essential, in fact, that if we don't get enough sleep for even one night, we may struggle to think, react, and otherwise make it through the day.

11 Apr 2023

Bonn researchers elucidate a mechanism underlying cisplatin resistance in testicular cancer

Cisplatin is used successfully in the chemotherapy of testicular cancer. However, patients who develop resistance to the cytostatic drug urgently need alternative therapy options.

11 Apr 2023

Daily statin medication could improve cardiovascular outcomes in people with HIV

A National Institutes of Health clinical trial was stopped early because a daily statin medication was found to reduce the increased risk of cardiovascular disease among people living with HIV in the first large-scale clinical study to test a primary cardiovascular prevention strategy in this population.

11 Apr 2023

Novel optical imaging approach provides four-dimensional view of cell secretions

Cell secretions like proteins, antibodies, and neurotransmitters play an essential role in immune response, metabolism, and communication between cells.

11 Apr 2023

Mutant Salmonella strains cause more severe infections than wild-type bacteria in chickens

In Brazil, a group of researchers supported by FAPESP created mutant forms of Salmonella to understand the mechanisms that favor colonization of the intestinal tract of chickens by these pathogenic bacteria and find better ways to combat the infection they cause.

11 Apr 2023

Cell News and Research

Researchers discover important drug target for preventing blood cancer

Study provides direct evidence of adaptive evolution in the skin microbiome

New potential therapeutic developed for diffuse intrinsic pontine glioma using ASO technology

Cedars-Sinai Cancer collaborates on a streamlined clinical trial design in Pragmatica-Lung Study

Researchers use a quick, portable process to produce promising virus-fighting protein

Pragmatica-Lung Study aims to increase accessibility to cancer clinical trials

Unexpected discovery could inspire new strategies for preventing liver disease and cancer

Acylceramides and protein-bound ceramides are vital for the formation of oral barrier in mice

Researchers conduct experiments comparing de novo proteins with computer-generated proteins

The identification of vaccinee-derived antibodies with broad-spectrum Omicron neutralization activity

New organoid platform could make vaccine screening quicker and greatly reduce animal testing

Optimized genome-editing method opens the door to more effective treatment of genetic diseases

Radioimmunotherapy cures human non-Hodgkin lymphoma in animal model

Bioprinting combined with AI allows to obtain high-quality homogenized in vitro models

Cornell receives $9.5 million NIH grant for chronic fatigue research

Exploring the tantalizing questions about sleep

Bonn researchers elucidate a mechanism underlying cisplatin resistance in testicular cancer

Daily statin medication could improve cardiovascular outcomes in people with HIV

Novel optical imaging approach provides four-dimensional view of cell secretions

Mutant Salmonella strains cause more severe infections than wild-type bacteria in chickens

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

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