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I-SPY2 research initiative employs exciting new model for testing breast cancer drugs

In a new paradigm of breast cancer research, physicians are fast-tracking promising new experimental drugs for further study, while immediately dropping drugs and drug combinations that don't work.

8 Jul 2016

Research opens up new ways to detect, inhibit cancer spread

Clusters of circulating cells commonly found in the blood of cancer patients have long been the subject of research on cancer. These clusters have been regarded for more than 50 years as malignant cells that have broken off from the primary tumor, spreading cancer to other parts of the body.

8 Jul 2016

Transplant drug rapamycin may reduce nerve damage, neuropathic pain after spinal cord injury

New research in mice indicates that a drug commonly used to suppress the immune system in recipients of organ transplants may also reduce tissue damage and neuropathic pain after spinal cord injury. The findings are published in the Journal of Orthopaedic Research.

8 Jul 2016

Study finds microRNA let-7 plays key role in restricting neuroblastoma

Great strides have been made in treating neuroblastoma, the most common cancer in infants and toddlers. However, advanced cases are often fatal, and children who survive often face life-long physical and intellectual challenges related to their treatment.

8 Jul 2016

UCLA researchers develop new combination therapy to activate immune response against glioblastoma

UCLA researchers have developed a new breakthrough combination treatment that utilizes a vaccine to activate an immune response against advanced brain tumors.

8 Jul 2016

Scientists identify how tumor cells exploit function of mitochondria to support cancer proliferation

As the powerhouse of the cells, mitochondria are critical for every organism because of their role in producing energy while also controlling survival, but how they function in cancer is still not completely known.

8 Jul 2016

Tumor DNA fragments in blood can help identify risk of colorectal cancer recurrence

Ludwig researchers working in collaboration with colleagues in Australia and the US have shown that fragments of tumor DNA circulating in the blood can be used to gauge the risk of colorectal cancer recurrence and the efficacy of chemotherapy following surgery.

7 Jul 2016

Relaxing acupressure improves fatigue levels in breast cancer survivors

Acupressure helped reduce persistent fatigue in women who had been treated for breast cancer, a new study finds.

7 Jul 2016

MGH researchers discover how obesity increases inflammation, desmoplasia in PDAC patients

Massachusetts General Hospital investigators have discovered the mechanism by which obesity increases inflammation and desmoplasia - an accumulation of connective tissue - in the most common form of pancreatic cancer.

7 Jul 2016

Innovative nanobubble treatment finds and destroys cancer cells in mice

Innovative technology developed by NIH-funded researchers has been able to find and facilitate the killing of cancer cells in mice without harming the nearby healthy tissue.

7 Jul 2016

Mitochondrial stress can trigger tumor-related metabolic shifts, study finds

Cancerous tumors must be fed. Their unregulated growth requires a steady stream of blood flow and nutrients. Thus, one way that researchers have tried to wipe out cancer is to target cells undergoing the metabolic shifts that enable a tumor's rapid growth.

7 Jul 2016

New study to investigate how genetic factors contribute to breast cancer disparities

The largest study ever to investigate how genetic and biological factors contribute to breast cancer risk among black women launched today.

7 Jul 2016

New microfluidic device allows scientists to use safe electric fields to treat cancer

Researchers at MIT's research center in Singapore have developed a new microfluidic device that tests the effects of electric fields on cancer cells.

7 Jul 2016

Genetic test detects colon cancer-linked DNA in blood to predict disease recurrence risk

Scientists at the Johns Hopkins Kimmel Cancer Center and University of Melbourne report they have used a genetic test that spots bits of cancer-related DNA circulating in the blood to accurately predict the likelihood of the disease's return in some — but not all — of a small group of patients with early-stage colon cancer.

7 Jul 2016

BU researcher receives grant to better understand breast cancer in African-American women

Why do African-American women die at a higher rate and experience more aggressive breast tumors than white women? Researchers from Boston University's Slone Epidemiology Center (SEC) have received funding from the National Cancer Institute to explore this question.

6 Jul 2016

Changes in benign tissue adjacent to prostate tumors could better predict recurrence

Changes in benign tissues next to prostate tumors may provide an early warning for patients at higher risk for biochemical recurrence after a radical prostatectomy, a study by researchers at Case Western Reserve University and Johns Hopkins Medical Institutions shows.

6 Jul 2016

Whole-genome omics data can improve accuracy of breast cancer survival predictions

Precise predictions of whether a tumor is likely to spread would help clinicians and patients choose the best course of treatment. But current methods fall short of the precision needed.

6 Jul 2016

Sleep disturbances, long sleep duration linked to inflammatory illnesses

A new meta-analysis in Biological Psychiatry reports that sleep disturbances and long sleep duration are associated with increases in markers of inflammation.

6 Jul 2016

European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

Amgen has announced that the European Commission (EC) has approved a variation to the marketing authorization for Kyprolis® (carfilzomib) to include use in combination with dexamethasone alone for adult patients with multiple myeloma who have received at least one prior therapy. The extended indication marks the second approval for Kyprolis by the EC in less than a year.

6 Jul 2016

Immunotherapy in conjunction with drugs could be effective in treating pancreatic cancer

While immune therapy has proven effective in treating certain types of cancer, especially lung cancer and melanoma, tumors of the pancreas remain among the most difficult to treat and, so far, are impervious to immune-based therapies.

4 Jul 2016

Tumor News and Research

I-SPY2 research initiative employs exciting new model for testing breast cancer drugs

Research opens up new ways to detect, inhibit cancer spread

Transplant drug rapamycin may reduce nerve damage, neuropathic pain after spinal cord injury

Study finds microRNA let-7 plays key role in restricting neuroblastoma

UCLA researchers develop new combination therapy to activate immune response against glioblastoma

Scientists identify how tumor cells exploit function of mitochondria to support cancer proliferation

Tumor DNA fragments in blood can help identify risk of colorectal cancer recurrence

Relaxing acupressure improves fatigue levels in breast cancer survivors

MGH researchers discover how obesity increases inflammation, desmoplasia in PDAC patients

Innovative nanobubble treatment finds and destroys cancer cells in mice

Mitochondrial stress can trigger tumor-related metabolic shifts, study finds

New study to investigate how genetic factors contribute to breast cancer disparities

New microfluidic device allows scientists to use safe electric fields to treat cancer

Genetic test detects colon cancer-linked DNA in blood to predict disease recurrence risk

BU researcher receives grant to better understand breast cancer in African-American women

Changes in benign tissue adjacent to prostate tumors could better predict recurrence

Whole-genome omics data can improve accuracy of breast cancer survival predictions

Sleep disturbances, long sleep duration linked to inflammatory illnesses

European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

Immunotherapy in conjunction with drugs could be effective in treating pancreatic cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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