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Study ignores possibility that drugs, chemicals affect sexes differently

Many of the medicines we take were only ever tested on men during clinical studies. This poses a distinct danger that females are receiving suboptimal care—and that treatments specifically benefiting women are going undiscovered.

15 Jun 2016

CT-derived SULps can improve accuracy of PET imaging in advanced cancer patients

Cancer patients often experience significant fluctuations in weight and lean body mass (LBM). Neglecting to account for these changes can prevent clinicians from obtaining precise data from molecular imaging, but a new method of measuring LBM takes changes in individual body composition into account for better staging of disease and therapy monitoring, say researchers at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging.

15 Jun 2016

Interdisciplinary approach to improve cancer treatments

Whether it focuses on determining why certain cancers develop drug resistance, finding a way to improve individual's immune systems or better understanding cancer cell evolution, fundamental scientific research will "stand up to cancer" with three new awards from the National Science Foundation.

15 Jun 2016

PharmaMar announces initiation of pivotal plitidepsin clinical trial in patients with T-cell lymphomas

PharmaMar today announced the start of a multicenter, prospective, pivotal study to analyze the efficacy of the antitumoral compound of marine origin, plitidepsin in patients with relapsed and refractory angioimmunoblastic T-cell lymphoma.

15 Jun 2016

Four miRNAs may hold vital clue to disease progression in gliobastoma

Scientists at the Helmholtz Zentrum München and the Ludwig Maximilians University of Munich have developed a new method of predicting disease progression in gliobastoma patients who have undergone standard treatment.

14 Jun 2016

FDG-PET imaging tracks ability of atezolizumab to bolster immunity against NSCLC

Non-small cell lung cancers have a collective reputation for not responding very well to chemotherapy. Researchers at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) are presenting a means of evaluating an immunotherapy that fights off NSCLC by strengthening a patient's own immune system.

14 Jun 2016

Molecular imaging technique could help optimize radiotherapy dose to combat NETs

Aggressive neuroendocrine cancer is something of a dark horse--a rare, elusive and persevering force linked to discouraging long-term survival rates.

14 Jun 2016

Databases of proteins' 3-D shapes help identify more than 850 DNA mutations linked to cancer

Examining databases of proteins' 3-D shapes, scientists at Washington University School of Medicine in St. Louis have identified more than 850 DNA mutations that appear to be linked to cancer.

14 Jun 2016

EPFL researchers reprogram TAMs to prevent tumor metastasis

One of the major obstacles with treating cancer is that tumors can conscript the body's immune cells and make them work for them. Researchers at EPFL have now found a way to reclaim the corrupted immune cells, turn them into signals for the immune system to attack the tumor, and even prevent metastasis.

14 Jun 2016

Adjuvant chemotherapy use benefits early-stage NSCLC patients

The use of adjuvant chemotherapy in early-stage non-small cell lung cancer (NSCLC) patients improves overall survival (OS) and 5-year OS in patients with tumor sizes ranging from 3 - 7 cm.

14 Jun 2016

Researchers aim to protect kidneys while improving cisplatin's efficacy against cancer

Cisplatin is a common, powerful chemotherapy agent used for a wide range of cancers such as breast, ovarian and lung, that in a handful of days can also permanently damage or destroy patients' kidneys.

14 Jun 2016

New nano-fabricated platform provides accurate post-surgery prognosis for glioblastoma patients

A new nano-fabricated platform for observing brain cancer cells provides a much more detailed look at how the cells migrate and a more accurate post-surgery prognosis for brain cancer (glioblastoma) patients.

14 Jun 2016

Study underscores importance of developing PRMT5 inhibitors as promising treatment for GB patients

A new study suggests that blocking an enzyme called PRMT5 in tumor cells could be a promising new strategy for the treatment of glioblastoma (GB), the most aggressive and lethal form of brain cancer.

14 Jun 2016

Study opens up new strategy to make immunotherapy more effective for different cancer types

By combining local radiation therapy and anti-cancer vaccines with checkpoint inhibitors, researchers from the University of Chicago, working with mice, were able to increase the response rate for these new immunotherapy agents.

14 Jun 2016

Genetic blood test can help predict patient’s respone to neuroendocrine cancer therapy

Malignant neuroendocrine tumors (NETs) are relatively rare, notoriously difficult to treat, and associated with poor long-term survival. According to research presented at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging, an investigative blood test could predict how patients will respond to peptide receptor radionuclide therapy (PRRT) before they commit to a course of treatment.

14 Jun 2016

Novel radioimmunotherapy may help cure colorectal cancer

An emerging cancer therapy has colorectal tumors surrounded. Presenters at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging are unveiling a novel radioimmunotherapy that combines a cancer-seeking antibody with potent radionuclide agents, resulting in complete remission of colorectal cancer in mouse models.

14 Jun 2016

Anti-TNF therapy offers new hope to JDM patients

The results of a UK study presented today at the European League Against Rheumatism Annual Congress showed that tumour necrosis factor inhibitor (anti-TNF) treatment is effective at improving both muscle and skin involvement in children with juvenile dermatomyositis (JDM).

13 Jun 2016

Using Spectral Imaging to Study Brain Tumors in 3D

I’m a biophysicist at the University of Bordeaux and I mainly work on bio-imaging methods in the cancer laboratory research facility, mostly for brain cancers.

From Daylight Solutions Inc 13 Jun 2016

Johns Hopkins researchers develop lab test that accurately predicts glioblastoma aggression and spread

Johns Hopkins Medicine researchers report they have developed an experimental laboratory test that accurately clocks the “speed” of human brain tumor cell movement along a small glass “track.”

13 Jun 2016

PI3K/AKT/mTOR pathway plays key role in prostate tumor growth and progression

The research article - Targeting the PI3K/AKT/mTOR Pathway in Prostate Cancer Development and Progression: Insight to Therapy, by Dr Claudio Festuccia and published in Clinical Cancer Drugs, volume 3, issue 1 - discusses experimental and clinical data on the pharmacological inhibition of the Akt/mTOR pathways.

13 Jun 2016

Tumor News and Research

Study ignores possibility that drugs, chemicals affect sexes differently

CT-derived SULps can improve accuracy of PET imaging in advanced cancer patients

Interdisciplinary approach to improve cancer treatments

PharmaMar announces initiation of pivotal plitidepsin clinical trial in patients with T-cell lymphomas

Four miRNAs may hold vital clue to disease progression in gliobastoma

FDG-PET imaging tracks ability of atezolizumab to bolster immunity against NSCLC

Molecular imaging technique could help optimize radiotherapy dose to combat NETs

Databases of proteins' 3-D shapes help identify more than 850 DNA mutations linked to cancer

EPFL researchers reprogram TAMs to prevent tumor metastasis

Adjuvant chemotherapy use benefits early-stage NSCLC patients

Researchers aim to protect kidneys while improving cisplatin's efficacy against cancer

New nano-fabricated platform provides accurate post-surgery prognosis for glioblastoma patients

Study underscores importance of developing PRMT5 inhibitors as promising treatment for GB patients

Study opens up new strategy to make immunotherapy more effective for different cancer types

Genetic blood test can help predict patient’s respone to neuroendocrine cancer therapy

Novel radioimmunotherapy may help cure colorectal cancer

Anti-TNF therapy offers new hope to JDM patients

Using Spectral Imaging to Study Brain Tumors in 3D

Johns Hopkins researchers develop lab test that accurately predicts glioblastoma aggression and spread

PI3K/AKT/mTOR pathway plays key role in prostate tumor growth and progression

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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