Genes News and Research

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Study: Neural signal that urges to eat overpowers the one that says to stop

Almost everyone knows the feeling. You're at a restaurant or a holiday meal, and your stomach is telling you it's full, so logically you know you should stop eating.

21 Sep 2018

New research finds that MHC-II molecules have more influence on tumors than MHC-I

Cancer immunotherapy -- efforts to boost a patient's own immune system, allowing it to better fight cancer cells on its own -- has shown great promise for some previously intractable cancers.

21 Sep 2018

Salk Institute researchers uncover molecular structure of RNA-based CRISPR system

Over the past several years, CRISPR-Cas9 has moved beyond the lab bench and into the public zeitgeist. This gene-editing tool CRISPR-Cas9 holds promise for correcting defects inside individual cells and potentially healing or preventing many human ailments.

20 Sep 2018

Novel mathematical approach uncovers existence of unsuspected biological cycles

A novel mathematical approach has uncovered that some animal cells have robust 12-hour cycles of genetic activity, in addition to circadian or 24-hour cycles.

20 Sep 2018

Sea squirt model reveals key molecules in dopaminergic neuron differentiation

The human brain is exceedingly complex, consisting of various regions with particular functions and approximately 100 billion neurons. This complexity has presented a major challenge in understanding this organ and how it develops, particularly in view of the ethical issues associated with research on humans.

20 Sep 2018

Study reveals new way to target HER2-negative metastatic breast cancer

A cytokine signature found in certain kinds of breast cancer cells can not only serve as a diagnostic tool for HER2-negative cancers but also offer an effective treatment target.

20 Sep 2018

CWRU receives NIH grant to learn how non-coding genes contribute to spread of colorectal cancer

Certain genes that code for proteins have long been known to contribute to cancer progression. But in a frame shift, researchers from Case Western Reserve University School of Medicine recently found that non-coding genes also contribute to the development and spreading of the disease, one of the first known examples of researchers doing so.

20 Sep 2018

Finding epigenetic signature appears to predict inflammation risk in serious type of IBD

With an estimated 1.6 million people in the U.S. dealing with inflammatory bowel disease (IBD), physicians can have a hard time telling which newly diagnosed patients have a high risk of severe inflammation or what therapies will be most effective.

20 Sep 2018

LineaRx signs agreement with Takis/Evvivax to develop linear-DNA based anti-cancer vaccines

Applied DNA Sciences Inc. announced today that LineaRx, Inc., its wholly-owned subsidiary focused on next-generation biotherapeutics, has signed a Joint Development Agreement with Takis S.R.L. and Evvivax S.R.L., biotechnology companies focused on the discovery and development of DNA based anti-cancer vaccines for the human and animal markets, respectively.

20 Sep 2018

Celltrion and Emory University sign 'Incubation' agreement to develop new drug candidates for atherosclerosis

Celltrion, Inc. signed an 'Incubation' agreement with Emory University in Atlanta to support the research and development of new drug candidates for atherosclerosis.

20 Sep 2018

Study finds factors within cell influencing variability in amount of protein produced

You can think of a cell in your body like a miniature factory, creating a final product called proteins, which carry out various tasks and functions.

20 Sep 2018

New study focuses on two-way gene switches controlling gene activity

Led by ICREA research professors at the Centre for Genomic Regulation, Luciano Di Croce and Marc A. Marti-Renom, the study focused on a set of genes with what's known as bivalent promoters - two-way genetic 'control switches' that are poised either to turn on in early development and rapidly drive high levels of gene activity, or to switch off and shut down the gene completely.

20 Sep 2018

First U.S. patient treated with innovative gene therapy at Bascom Palmer Eye Institute

A Puerto Rican patient with X-linked retinitis pigmentosa (XLRP) is hoping to save his vision after an innovative gene therapy procedure at Bascom Palmer Eye Institute at the University of Miami Miller School of Medicine.

19 Sep 2018

Antioxidant in green tea helps sneak therapeutic RNAs into cells

Drinking green tea has been linked to health benefits ranging from cardiovascular disease prevention to weight loss.

19 Sep 2018

Manipulating nuclear pore number could lead to new way of treating cancer

Researchers at the Salk institute have found a way to manipulate the number of nuclear pores present in the perimeter of the nucleus.

19 Sep 2018

Study finds why some human genes are more popular with biomedical researchers

Historical bias is a key reason why biomedical researchers continue to study the same 10 percent of all human genes while ignoring many genes known to play roles in disease, according to a study publishing September 18 in the open access journal PLOS Biology, led by Thomas Stoeger and Luís Amaral of Northwestern University, and colleagues. This bias is bolstered by research funding mechanisms and social forces.

19 Sep 2018

Researchers describe cell mechanism that optimizes proteins production in stressful situations

The different genes within the genome must be expressed in precise levels and in the exact moment if the complex balance regulating cell activity is to be maintained.

19 Sep 2018

Women with high levels of anti-Müllerian hormone more likely to develop breast cancer

Having high levels of anti-Müllerian hormone – a hormone that indicates the size of a woman’s ovarian reserve – before the menopause is associated with an increased risk of breast cancer, new research suggests.

19 Sep 2018

Penn researchers find common thread linking almost all TNR expansion diseases

In a class of roughly 30 neurological disorders that includes ALS, Huntington's Disease and Fragile X Syndrome, the relevant mutant gene features sections of repeating base pair sequences known as short tandem repeats, or STRs. Healthy people have STRs of normal lengths distributed across their DNA.

19 Sep 2018

Scientists discover new molecules that work together to remove unwanted DNA

Scientists have discovered a new family of molecules that work together to precisely remove unwanted DNA during reproduction in single-celled, freshwater organisms called ciliates.

19 Sep 2018

Genes News and Research

Study: Neural signal that urges to eat overpowers the one that says to stop

New research finds that MHC-II molecules have more influence on tumors than MHC-I

Salk Institute researchers uncover molecular structure of RNA-based CRISPR system

Novel mathematical approach uncovers existence of unsuspected biological cycles

Sea squirt model reveals key molecules in dopaminergic neuron differentiation

Study reveals new way to target HER2-negative metastatic breast cancer

CWRU receives NIH grant to learn how non-coding genes contribute to spread of colorectal cancer

Finding epigenetic signature appears to predict inflammation risk in serious type of IBD

LineaRx signs agreement with Takis/Evvivax to develop linear-DNA based anti-cancer vaccines

Celltrion and Emory University sign 'Incubation' agreement to develop new drug candidates for atherosclerosis

Study finds factors within cell influencing variability in amount of protein produced

New study focuses on two-way gene switches controlling gene activity

First U.S. patient treated with innovative gene therapy at Bascom Palmer Eye Institute

Antioxidant in green tea helps sneak therapeutic RNAs into cells

Manipulating nuclear pore number could lead to new way of treating cancer

Study finds why some human genes are more popular with biomedical researchers

Researchers describe cell mechanism that optimizes proteins production in stressful situations

Women with high levels of anti-Müllerian hormone more likely to develop breast cancer

Penn researchers find common thread linking almost all TNR expansion diseases

Scientists discover new molecules that work together to remove unwanted DNA

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