Carcinoma News and Research

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Carcinoma is cancer that begins in the skin or in tissues that line or cover internal organs.

A new book on ovarian cancer

An opening discussion of contemporary management of this disease presents commentary on surgery and clinical trials: neoadjuvant, dose-dense, and heated intraperitoneal chemotherapy (HIPEC}, as well as immunotherapy, vaccine therapy, emerging therapies.

18 Dec 2019

Using math equations to detect and forecast liver cancer risk

The use of mathematical modeling in the study of biological systems has become a challenging and rewarding field of research as it yields many unknown pieces of information. A new study published online on December 16, 2019, in the journal Proceedings of the National Academy of Science (PNAS).

17 Dec 2019

Targeting specific nuclear transport systems may lead to possible therapeutic strategies for cancer

Although less often the focus of cancer research, recent studies have hinted at the possible importance of a type of protein known as nuclear transport receptors.

17 Dec 2019

Discovery of novel mechanism by which certain breast cancers can metastasize

Researchers from the Baylor College of Medicine and Harvard Medical School have found a novel mechanism to explain the resistance of certain breast cancers that spread in the major organs of the body. They hope that this would help develop new therapeutic strategies to treat the cancer.

12 Dec 2019

Extensive tumor protein analysis reveals potential new players in cancer

Looking to gain a deeper understanding of cancer, a team led by researchers at Baylor College of Medicine conducted an extensive computational analysis of the similarities and differences in the entire set of proteins, called the proteome, of more than 500 cancers from five different tissue sites.

12 Dec 2019

Radiation therapy alone found to be cost-effective for treatment of DCIS

Ductal carcinoma in-situ (DCIS) accounts for one-fifth of breast cancer cases in the United States, according to the American Cancer Society.

11 Dec 2019

Shorter course of high-dose radiation treatment shows promise in breast cancer patients

A shorter course of higher-dose radiation treatment to part of the breast is showing promise in women with early-stage breast cancer who undergo breast conserving surgery, says a study led by Hamilton researchers.

6 Dec 2019

Study reports first guidelines for treating rare skin tumor

It starts as a yellow or shiny bump on the eyelids, face or body that grows and doesn't go away, unlike a pimple.

5 Dec 2019

Researchers investigate NOTCH1 mutations in keratinocyte lines derived from OSCC biopsies

The cover for issue 63 of Oncotarget features Figure 6, "Inverse relationship between ETV7 and SERPINE1 in OSCC," by Salameti, et al.

4 Dec 2019

Experimental drug better for repeat kidney cancer patients than FDA-approved equivalent

Kidney cancer patients who had already tried two or three different treatments had improved chances of preventing cancer progression with an experimental drug called tivozanib compared to an alternative approved by the U.S. Food and Drug Administration, according to a City of Hope-led study.

4 Dec 2019

ACCC project develops resources to support treatment of patients with cutaneous squamous cell carcinoma

Due to the rarity of advanced cutaneous squamous cell carcinoma (cSCC), staying current with the latest information on diagnosing, treating, and supporting patients with this diagnosis can be challenging for clinicians who do not often encounter advanced cSCC in practice.

4 Dec 2019

Smoking cannabis increases testicular cancer risk

Men who regularly smoke cannabis increase their risk of developing testicular cancer, according to a new study published in the Journal of the American Medical Association (JAMA).

2 Dec 2019

Women treated for early-stage breast cancer may develop invasive breast cancer

New research in the November 2019 issue of JNCCN—Journal of the National Comprehensive Cancer Network examines the implications of invasive breast cancer after breast-conserving treatment for ductal carcinoma in situ (aka DCIS, a form of non-invasive breast cancer) and which factors could impact overall survival.

25 Nov 2019

Apoptosis protein API-5 more markedly expressed in chemoresistant triple-negative breast cancer

78 TNBC biopsies from patients with different responses to chemotherapy were analysed for API-5 expression before any treatment.

25 Nov 2019

Combination therapy improves survival in patients with hepatocellular carcinoma

Combination therapy with the PD-L1 inhibitor atezolizumab and the VEGF inhibitor bevacizumab significantly improves overall survival and progression-free survival in patients with unresectable hepatocellular carcinoma compared to standard of care, showed results from a phase 3 study reported at the ESMO Asia 2019 Congress.

22 Nov 2019

Subpopulations of tumor cells may exhibit diverging behaviors from bulk tumor

Subpopulations of tumor cells may exhibit diverging behaviors from the bulk tumor due to an alternate stress response that diverts tumor cells from apoptotic death.

20 Nov 2019

Woman’s velvety tripe palms turn out to be a sign of lung cancer

A 73-year-old woman presented with pruritic, itchy, and painful lesions on her hand, showing an appearance consisted of tripe palms. It was later revealed by doctors that her velvety palms turned out to be a rare sign of lung cancer.

19 Nov 2019

Improving the efficiency of antiangiogenic and antifibrotic drug for treatment of lung cancer

The University of Barcelona and Hospital Clínic de Barcelona collaborate with Boehringer Ingelheim Inc. to improve the efficiency of nintedanib, an antiangiogenic and antifibrotic drug, for the treatment of lung cancer.

19 Nov 2019

Anal cancer diagnoses and death rates have increased dramatically over the last 15 years

Rates of new anal cancer diagnoses and deaths related to human papillomavirus, the most common sexually transmitted infection, have increased dramatically over the last 15 years, according to researchers at The University of Texas Health Science Center at Houston.

19 Nov 2019

Clinical analysis reveals high expression of apoptosis protein in chemoresistant TNBC

78 TNBC biopsies from patients with different responses to chemotherapy were analysed for API-5 expression before any treatment.

13 Nov 2019

Carcinoma News and Research

Further Reading

A new book on ovarian cancer

Using math equations to detect and forecast liver cancer risk

Targeting specific nuclear transport systems may lead to possible therapeutic strategies for cancer

Discovery of novel mechanism by which certain breast cancers can metastasize

Extensive tumor protein analysis reveals potential new players in cancer

Radiation therapy alone found to be cost-effective for treatment of DCIS

Shorter course of high-dose radiation treatment shows promise in breast cancer patients

Study reports first guidelines for treating rare skin tumor

Researchers investigate NOTCH1 mutations in keratinocyte lines derived from OSCC biopsies

Experimental drug better for repeat kidney cancer patients than FDA-approved equivalent

ACCC project develops resources to support treatment of patients with cutaneous squamous cell carcinoma

Smoking cannabis increases testicular cancer risk

Women treated for early-stage breast cancer may develop invasive breast cancer

Apoptosis protein API-5 more markedly expressed in chemoresistant triple-negative breast cancer

Combination therapy improves survival in patients with hepatocellular carcinoma

Subpopulations of tumor cells may exhibit diverging behaviors from bulk tumor

Woman’s velvety tripe palms turn out to be a sign of lung cancer

Improving the efficiency of antiangiogenic and antifibrotic drug for treatment of lung cancer

Anal cancer diagnoses and death rates have increased dramatically over the last 15 years

Clinical analysis reveals high expression of apoptosis protein in chemoresistant TNBC

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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