Fracture News and Research

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Merck announces update on odanacatib Phase III trial for osteoporosis

Merck, known as MSD outside the United States and Canada, announced today an update on the Phase III trial assessing fracture risk reduction with odanacatib, Merck's investigational cathepsin K (cat-K) inhibitor.

12 Jul 2012

Mechanical treatment shows promise in thalassemia

Vibration therapy may be an effective nonpharmacologic intervention to increase bone mass in patients with thalassemia, US researchers report

10 Jul 2012

High-dose vitamin D recommended for over 65s

Meta-analysis findings support recommendations from the Institute of Medicine that people aged 65 years and older should routinely receive 800 IU of vitamin D per day.

10 Jul 2012

High ferritin warns of bone loss

Individuals with high levels of ferritin, an indicator of iron stores within the body, have accelerated bone loss at the proximal femur, Korean researchers report.

10 Jul 2012

$Vertebral fracture more common among Chinese women than men$

Vertebral fracture more common among Chinese women than men

Vertebral deformities occur at a similar rate among Chinese men and women aged 65 years or older, research findings show.

10 Jul 2012

$Vertebroplasty can benefit patients with osteoporotic vertebral compression fractures$

Vertebroplasty can benefit patients with osteoporotic vertebral compression fractures

An analysis of published data in the medical literature has found that vertebroplasty can provide more pain relief and better function for patients with osteoporotic vertebral compression fractures than nonoperative treatments.

10 Jul 2012

$Higher doses of Vitamin D may be most beneficial in reducing bone fractures in older adults$

Higher doses of Vitamin D may be most beneficial in reducing bone fractures in older adults

Based on the results of a pooled analysis of 11 unrelated randomized clinical trials investigating vitamin D supplementation and fracture risk in more than 31,000 older adults, Bess Dawson-Hughes, MD, director of the Bone Metabolism Laboratory at the Jean Mayer USDA Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University, says higher doses of Vitamin D may be the most beneficial in reducing bone fractures in this age group.

6 Jul 2012

$Researchers report positive effects of ibuprofen on bone repair after fracture or surgery$

Researchers report positive effects of ibuprofen on bone repair after fracture or surgery

A study conducted at the University of Granada has demonstrated that ibuprofen -a non-steroidal anti-inflammatory drug (NSAID)- has beneficial effects on bone repair after a fracture or following bone surgery.

3 Jul 2012

Wright Medical launches ORTHOLOC 3Di Plating System for foot and ankle surgery

Wright Medical Group, Inc., a global orthopaedic medical device company, today announced the full commercial launch of the ORTHOLOC 3Di Reconstruction Plating System for foot and ankle surgery.

3 Jul 2012

Vitamin D–calcium combo reduces mortality in elderly

The results of a meta-analysis of individual patient data show that vitamin D supplementation with calcium reduces mortality rates in the elderly.

2 Jul 2012

$Simple tests may ease scaphoid fracture assessment$

Simple tests may ease scaphoid fracture assessment

Researchers have devised a clinical prediction rule that can help physicians assess patients with a suspected scaphoid fracture.

29 Jun 2012

$Epilepsy patients unaware of fracture risk$

Epilepsy patients unaware of fracture risk

Few patients with epilepsy are aware that taking anti-epileptic drugs puts them at increased risk for falls and fractures, report researchers.

29 Jun 2012

Young inflammatory bowel disease patients have low bone mass

Children and adolescents with inflammatory bowel disease have significantly lower bone mineral density than their healthy peers, even after adjusting for pubertal delay, Finnish researchers report.

29 Jun 2012

$Study sheds light on increased risk of fractures and falls among epilepsy patients using AEDs$

Study sheds light on increased risk of fractures and falls among epilepsy patients using AEDs

New research has shed light on the high risk of fractures, falls, and osteoporosis among epilepsy patients using antiepileptic drugs (AEDs) with most patients unaware of the risks associated with taking the drugs.

29 Jun 2012

Young inflammatory bowel disease patients have low bone mass

Children and adolescents with inflammatory bowel disease have significantly lower bone mineral density than their healthy peers, even after adjusting for pubertal delay, Finnish researchers report.

28 Jun 2012

$Chinese herbal preparation reduces fragility fractures$

Chinese herbal preparation reduces fragility fractures

Herbal Fufang – a multi-herbal preparation used in traditional Chinese medicine –increases bone mineral density and reduces fragility fractures in postmenopausal women, Chinese researchers report.

27 Jun 2012

$Postoperative hemoglobin predicts hospital stay after hip fracture surgery$

Postoperative hemoglobin predicts hospital stay after hip fracture surgery

Postoperative anemia is associated with longer hospital stays following surgery for hip fracture, Dutch researchers report.

26 Jun 2012

HIV therapy affects bone mass within 2 years

Young men receiving antiretroviral therapy for recently diagnosed HIV are more likely to have low bone mineral density than are other men of a similar age, US researchers report.

25 Jun 2012

$Hip fracture type may determine regional anesthesia benefits$

Hip fracture type may determine regional anesthesia benefits

Use of regional anesthesia may reduce the risk for mortality and pulmonary complications among patients undergoing surgery for hip fracture, research shows.

22 Jun 2012

$Hip fracture type may determine regional anesthesia benefits$

Hip fracture type may determine regional anesthesia benefits

Use of regional anesthesia may reduce the risk for mortality and pulmonary complications among patients undergoing surgery for hip fracture, research shows.

21 Jun 2012