Metabolites News and Research

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What are the effects of non-nutritive sweeteners on the human gut microbiome?

Researchers evaluated the short-term effects of four non-nutritive sweeteners on the human microbiome, glucose tolerance, and additional health parameters in a randomized-controlled trial encompassing 120 healthy adults.

24 Aug 2022

New treatment may help counteract food allergies and inflammatory diseases in future

Although many people with dietary allergies experience mild symptoms when exposed to triggering foods, some face potentially fatal consequences.

22 Aug 2022

Intake of lysine prevents hypertensive kidney disease in animal models

Can you eat your way out of a kidney disease? Perhaps you can – according to a new study from Aarhus University.

19 Aug 2022

Researchers report the effects of a common Japanese herbal remedy on colitis

Zhengzheng Shi and colleagues at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan report the effects of a common herbal remedy on colitis, one of two conditions that comprise inflammatory bowel disease (IBD).

18 Aug 2022

Eating disorders could be treated by modulating gut microbiota

Researchers describe how the gut-brain axis facilitates communication between the gastrointestinal tract and brain to regulate food consumption behaviors.

17 Aug 2022

Discovery explains how impaired metabolism triggers neuroendocrine tumors in the adrenal glands

Researchers have deciphered a signaling cascade through which inborn errors in metabolism provoke deadly neuroendocrine tumors in the adrenal glands.

16 Aug 2022

KAUST bioscientists develop new method to study the bone marrow microenvironment in greater detail

Deep molecular analysis of the bone marrow microenvironment reveals that the cells regulating blood stem cell maintenance are more diverse than expected and have features likely to be conserved between species.

16 Aug 2022

Here's why thinking hard exhausts you

Researchers elucidate the neuro-metabolic mechanisms responsible for cognitive fatigue that occurs following extended and intense working hours.

15 Aug 2022

Study offers more quantitative insights into long-term health risks of thirdhand smoke exposure

Some smells seem to seep into everything they touch. Tobacco smoke is one of the worst offenders.

15 Aug 2022

Study shows astrocytes as breeding grounds of SARS-CoV-2 during brain infection

Researchers evidenced the presence of SARS-CoV-2 in the human brain, infecting astrocytes and impairing neuronal function and viability.

15 Aug 2022

Post-illness metabolomic and gut-microbiome profiles in community-dwelling participants with SARS-CoV-2

Researchers explored post-illness gut-microbiome and metabolomic profiles of community COVID-19 cases and individuals with non-COVID-19 illnesses of prolonged duration.

15 Aug 2022

Remdesivir activates urotensin II receptor and induces cardiomyocyte dysfunction

In newly released research, scientists assessed the cardiac effects of remdesivir.

12 Aug 2022

New evidence explains why thinking hard makes one feel worn out

It's no surprise that hard physical labor wears you out, but what about hard mental labor? Sitting around thinking hard for hours makes one feel worn out, too.

11 Aug 2022

What is the association between polyfluoroalkyl substance exposure and risk of non-viral hepatocellular carcinoma?

The current study, published online in the journal JHEP Reports, looks at PFAS, which are endocrine disruptors and potential hepatotoxins.

11 Aug 2022

How ultraprocessed foods affect gut microbiome and health

Researchers describe the association between the consumption of ultraprocessed foods and chronic medical conditions.

10 Aug 2022

A low-energy, high FODMAP diet in prediabetes and diabetes?

Researchers summarize the available knowledge on FODMAPs and suggest that they can play a role in the prevention and treatment of diabetes.

10 Aug 2022

Researchers unravel a novel molecular target of eicosapentaenoic acid

Eicosapentaenoic acid (EPA) is an essential nutrient belonging to the omega-3 group of polyunsaturated fatty acids (PUFAs). As the human body cannot synthesize PUFAs, dietary supplements containing EPA are required for normal physiological functions. Found abundantly in natural sources like fish, hemp oil, and linseed oil, EPA is known to exhibit anti-inflammatory, neuroprotective, and cardiovascular protective activities.

9 Aug 2022

Locusts can differentiate between cancer cells and healthy cells, research shows

Researchers at Michigan State University have shown that locusts can not only "smell" the difference between cancer cells and healthy cells, but they can also distinguish between different cancer cell lines.

5 Aug 2022

Gut microbiota-derived metabolites offer protection against SARS-CoV-2

A new study investigated how the gut microbiome confers immunity to mammalian hosts against SARS-CoV-2 intranasal infection by generating short-chain fatty acids.

5 Aug 2022

Extracellular vesicle-based surface protein assay likely to lead to a better way to detect early-stage hepatocellular carcinoma

Primary liver cancer, the third-leading cause of cancer-related death worldwide, takes more than 30,000 lives in the United States each year. The high mortality rates can be attributed in part to the fact that a significant portion of the patients are detected at a late stage, when potentially curative treatments are no longer an option. Unfortunately, today's screening methods are not able to routinely provide accurate, early detection.

5 Aug 2022

Metabolites News and Research

What are the effects of non-nutritive sweeteners on the human gut microbiome?

New treatment may help counteract food allergies and inflammatory diseases in future

Intake of lysine prevents hypertensive kidney disease in animal models

Researchers report the effects of a common Japanese herbal remedy on colitis

Eating disorders could be treated by modulating gut microbiota

Discovery explains how impaired metabolism triggers neuroendocrine tumors in the adrenal glands

KAUST bioscientists develop new method to study the bone marrow microenvironment in greater detail

Here's why thinking hard exhausts you

Study offers more quantitative insights into long-term health risks of thirdhand smoke exposure

Study shows astrocytes as breeding grounds of SARS-CoV-2 during brain infection

Post-illness metabolomic and gut-microbiome profiles in community-dwelling participants with SARS-CoV-2

Remdesivir activates urotensin II receptor and induces cardiomyocyte dysfunction

New evidence explains why thinking hard makes one feel worn out

What is the association between polyfluoroalkyl substance exposure and risk of non-viral hepatocellular carcinoma?

How ultraprocessed foods affect gut microbiome and health

A low-energy, high FODMAP diet in prediabetes and diabetes?

Researchers unravel a novel molecular target of eicosapentaenoic acid

Locusts can differentiate between cancer cells and healthy cells, research shows

Gut microbiota-derived metabolites offer protection against SARS-CoV-2

Extracellular vesicle-based surface protein assay likely to lead to a better way to detect early-stage hepatocellular carcinoma

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