Red Blood Cells News and Research

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FibroGen presents China-based Phase 2 study data of roxadustat for treatment of CKD patients

FibroGen, Inc. (FibroGen), today announced that data from a China-based Phase 2 study of roxadustat (FG-4592), a first-in-class oral compound in late stage development for the treatment of anemia associated with chronic kidney disease (CKD) and end-stage renal disease (ESRD), were presented in an oral session at the 2013 American Society of Nephrology (ASN) Kidney Week in Atlanta, Georgia.

13 Nov 2013

Research: Chronic stress changes gene activity in immune cells before reaching bloodstream

New research shows that chronic stress changes gene activity in immune cells before they reach the bloodstream. With these changes, the cells are primed to fight an infection or trauma that doesn't actually exist, leading to an overabundance of the inflammation that is linked to many health problems.

6 Nov 2013

Scientists develop 3D filming technique that reveals spread of malaria

Scientists have developed a 3D filming technique that could help inform research to stem the spread of malaria.

5 Nov 2013

Array BioPharma reports net loss of $0.13 per share for first quarter of fiscal 2014

Array BioPharma Inc. today reported results for the first quarter of its fiscal year ending June 30, 2014.

31 Oct 2013

Researchers explore strategies that would optimize fresher blood for patients

Although clinical evidence is lacking on the relationship between the storage time of red blood cells and outcomes in transfused patients, the authors of a review article in the November 2013 issue of The Annals of Thoracic Surgery are advocating for a modernized blood management system—similar to inventory management systems seen in the retail sector—to potentially reduce patient complications.

31 Oct 2013

UofL researcher enters into license and research collaboration agreement with Novartis

The University of Louisville today announced that researcher Dr. Suzanne Ildstad, representing Regenerex LLC, has entered into a license and research collaboration agreement with Novartis to provide access to stem cell technology that has the potential to help transplant patients avoid taking anti-rejection medicine for life and could serve as a platform for treatment of other diseases.

31 Oct 2013

Study to assess benefits of plasma administration while being flown to hospitals

Vanderbilt University Medical Center will participate in a national trial to see if outcomes for critically injured patients with uncontrolled bleeding can be improved by administering plasma to these patients while in flight to the hospital.

30 Oct 2013

Research: Low levels of vitamin D appear to increase child's risk of anemia

Low levels of the "sunshine" vitamin D appear to increase a child's risk of anemia, according to new research led by investigators at the Johns Hopkins Children's Center. The study, published online Oct. 10 in the Journal of Pediatrics, is believed to be the first one to extensively explore the link between the two conditions in children.

22 Oct 2013

Discovery sheds light on how forces outside of cells get translated into internal signals

Johns Hopkins researchers used suction to learn that individual "molecular muscles" within cells respond to different types of force, a finding that may explain how cells "feel" the environment and appropriately adapt their shapes and activities.

21 Oct 2013

Opsumit drug receives FDA approval to treat adults with pulmonary arterial hypertension

The U.S. Food and Drug Administration today approved Opsumit (macitentan), a new drug to treat adults with pulmonary arterial hypertension (PAH), a chronic, progressive and debilitating disease that can lead to death or the need for lung transplantation.

19 Oct 2013

DIM compound derived from cruciferous vegetable protects rodents from radiation doses

Georgetown University Medical Center researchers say a compound derived from cruciferous vegetable such as cabbage, cauliflower and broccoli protected rats and mice from lethal doses of radiation.

15 Oct 2013

Scientists discover how to quantitatively observe cellular processes taking place on "lab on chip" devices

A team of scientists from The University of Texas at Arlington and MIT has figured out how to quantitatively observe cellular processes taking place on so-called "lab on a chip" devices in a silicon environment.

3 Oct 2013

PGI2 analogs, PDE5 inhibitors stimulate enhanced release of vasodilator ATP from human RBCs

Researchers at Saint Louis University School of Medicine have discovered a novel interaction between prostacyclin analogs and phosphodiesterase 5 inhibitors, two groups of drugs used in the treatment of pulmonary arterial hypertension.

21 Sep 2013

Study explains indirect burden of malaria on childhood deaths

Recurrent episodes of malaria cause chronic inflammation in blood vessels that might predispose to future infections and may increase susceptibility to cardiovascular disease, a Wellcome Trust study in Malawian children finds.

20 Sep 2013

WUSTL engineers apply new imaging technique to understand brain’s biomechanics

The human body has a lot of jobs to do, and its mechanical features, such as strength and flexibility, are important to how well it does them. Washington University in St. Louis engineers are now applying a new imaging technique to a model of brain tissue to see how stiff or soft it might be.

20 Sep 2013

Arginine therapy may be safe treatment for patients with sickle cell disease

Arginine therapy may be a safe and inexpensive treatment for acute pain episodes in patients with sickle cell disease, according to results of a recent clinical study. The study was the first randomized placebo-controlled study to demonstrate benefits of arginine therapy in children with sickle cell disease hospitalized for severe pain.

17 Sep 2013

Hydroxyurea treatment prevents complications, lowers medical care costs in children sickle cell disease

The benefits of hydroxyurea treatment in people with sickle cell disease are well known -- fewer painful episodes, fewer blood transfusions and fewer hospitalizations. Now new research from the Johns Hopkins Children's Center and other institutions reveals that by preventing such complications, the drug can also considerably lower the overall cost of medical care in children with this condition.

12 Sep 2013

International team of scientists discover new disease related to inability to process Vitamin B12

An international team of scientists, including University of Colorado School of Medicine and Children's Hospital Colorado researchers, has discovered a new disease related to an inability to process Vitamin B12.

6 Sep 2013

New recombinant antibody can recognize MSCs in umbilical cord blood

A new recombinant antibody can detect and isolate mesenchymal stem cells (MSCs), a nonembryonic source of stem cells with promising applications in tissue engineering, blood stem cell transplantation, and treatments for immune-mediated disorders.

4 Sep 2013

UCLA researchers receives $13M Early Translational grants to advance innovative discoveries using stem cells

Four researchers from UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have received Early Translational Research Awards totaling approximately $13 million from the California Institute for Regenerative Medicine, the state's stem cell agency. The UCLA researchers received four of the 12 total awards; no other institution received more than one.

4 Sep 2013

Red Blood Cells News and Research

FibroGen presents China-based Phase 2 study data of roxadustat for treatment of CKD patients

Research: Chronic stress changes gene activity in immune cells before reaching bloodstream

Scientists develop 3D filming technique that reveals spread of malaria

Array BioPharma reports net loss of $0.13 per share for first quarter of fiscal 2014

Researchers explore strategies that would optimize fresher blood for patients

UofL researcher enters into license and research collaboration agreement with Novartis

Study to assess benefits of plasma administration while being flown to hospitals

Research: Low levels of vitamin D appear to increase child's risk of anemia

Discovery sheds light on how forces outside of cells get translated into internal signals

Opsumit drug receives FDA approval to treat adults with pulmonary arterial hypertension

DIM compound derived from cruciferous vegetable protects rodents from radiation doses

Scientists discover how to quantitatively observe cellular processes taking place on "lab on chip" devices

PGI2 analogs, PDE5 inhibitors stimulate enhanced release of vasodilator ATP from human RBCs

Study explains indirect burden of malaria on childhood deaths

WUSTL engineers apply new imaging technique to understand brain’s biomechanics

Arginine therapy may be safe treatment for patients with sickle cell disease

Hydroxyurea treatment prevents complications, lowers medical care costs in children sickle cell disease

International team of scientists discover new disease related to inability to process Vitamin B12

New recombinant antibody can recognize MSCs in umbilical cord blood

UCLA researchers receives $13M Early Translational grants to advance innovative discoveries using stem cells

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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