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Patients with eye diseases can benefit from ArtCornea

Blindness is often caused by corneal diseases. The established treatment is a corneal transplant, but in many cases this is not possible and donor corneas are often hard to come by. In the future, an artificial cornea could make up for this deficiency and save the vision of those affected.

5 Oct 2012

Study reveals atomic-level structure of the human peptidase enzyme meprin β

An international research team led by the Spanish National Research Council (CSIC) and researchers from Kiel University revealed the atomic-level structure of the human peptidase enzyme meprin β (beta).

5 Oct 2012

Countering neuroinflammation is indeed a potential therapeutic strategy for Alzheimer's

New research proves the validity of one of the most promising approaches for combating Alzheimer's disease (AD) with medicines that treat not just some of the symptoms, but actually stop or prevent the disease itself, scientists are reporting. The study, in the journal ACS Medicinal Chemistry Letters, also identifies a potential new oral drug that the scientists say could lead the way.

5 Oct 2012

Simple new test can monitor treatment of eosinophilic esophagitis

A simple new test, in which the patient swallows a string, can monitor treatment of eosinophilic esophagitis as effectively as an invasive, expensive and uncomfortable procedure that risks complications, particularly in children.

4 Oct 2012

Modulating immune response to injury could accelerate regeneration of peripheral nerves

Modulating immune response to injury could accelerate the regeneration of severed peripheral nerves, a new study in an animal model has found. By altering activity of the macrophage cells that respond to injuries, researchers dramatically increased the rate at which nerve processes regrew.

4 Oct 2012

Rare study highlights anal cancer prognosis risks

The presence of palpable, clinically involved inguinal lymph nodes and male gender are both independent risk factors for poor prognosis in anal cancer, confirm the results of a UK analysis.

3 Oct 2012

LpxC-1 can effectively treat antibiotic-resistant infections

A new type of antibiotic can effectively treat an antibiotic-resistant infection by disarming instead of killing the bacteria that cause it. Researchers report their findings in the October 2 issue of mBio-, the online open-access journal of the American Society for Microbiology.

3 Oct 2012

DFG-funded project to research into complex regional pain syndrome

German Research Foundation funds a three-year joint project of the Mainz University Medical Center and the University of Münster to the tune of about EUR 460,000.

3 Oct 2012

Multiple sclerosis symptoms worse in those with low vitamin D levels

Low blood levels of vitamin D are associated with an increased number of brain lesions and signs of a more active disease state in people with multiple sclerosis (MS), a new study finds, suggesting a potential link between intake of the vitamin and the risk of longer-term disability from the autoimmune disorder.

3 Oct 2012

Eating apples might help keep the cardiologist away

Eating an apple a day might in fact help keep the cardiologist away, new research suggests.

3 Oct 2012

Zinc deficiency mechanism associated with many health problems, aging

A new study has outlined for the first time a biological mechanism by which zinc deficiency can develop with age, leading to a decline of the immune system and increased inflammation associated with many health problems, including cancer, heart disease, autoimmune disease and diabetes.

2 Oct 2012

Omega-3 fatty acid supplements could slow key biological process linked to aging

Taking enough omega-3 fatty acid supplements to change the balance of oils in the diet could slow a key biological process linked to aging, new research suggests.

2 Oct 2012

Researchers identify how p110delta molecule controls the body's inflammatory responses

Researchers at Queen Mary, University of London have discovered how a key molecule controls the body's inflammatory responses. The molecule, known as p110delta, fine-tunes inflammation to avoid excessive reactions that can damage the organism.

1 Oct 2012

Researchers identify IL-27 molecule involved in counterbalancing the immune system attack

We couldn't live without our immune systems, always tuned to detect and eradicate invading pathogens and particles. But sometimes the immune response goes overboard, triggering autoimmune diseases like lupus, asthma or inflammatory bowel disease.

29 Sep 2012

FDA approves Abbott’s HUMIRA to treat ulcerative colitis

Abbott today announced that the U.S. Food and Drug Administration (FDA) has approved HUMIRA (adalimumab) for inducing and sustaining clinical remission in adult patients with moderately to severely active ulcerative colitis (UC) when certain other medicines have not worked well enough.

29 Sep 2012

Abbott receives FDA approval for Humira to treat ulcerative colitis

The U.S. Food and Drug Administration today expanded the approved use of Humira (adalimumab) to include treatment of moderate-to-severe ulcerative colitis in adults.

29 Sep 2012

Cholesterol precursor suppresses inflammatory response genes, causes atherosclerosis

Atherosclerosis - the hardening of arteries that is a primary cause of cardiovascular disease and death - has long been presumed to be the fateful consequence of complicated interactions between overabundant cholesterol and resulting inflammation in the heart and blood vessels.

28 Sep 2012

Researchers reduce life-threatening complication of stem cell transplants in mice with leukemia

Studying leukemia in mice, researchers at Washington University School of Medicine in St. Louis have reduced a life-threatening complication of stem cell transplants, the only curative treatment when leukemia returns.

28 Sep 2012

Inhibiting TRPV4 protects against diet-induced obesity, inflammation and insulin resistance

Ember Therapeutics, Inc., a company harnessing breakthroughs in brown fat biology and insulin sensitization to revolutionize the treatment of metabolic disease, today announced the publication of key preclinical data demonstrating that inhibition of the Transient Receptor Potential Vanilloid (TRPV) family of ion channels - specifically TRPV4 - resulted in activation of brown/beige fat and protection from diet-induced obesity, inflammation and insulin resistance. Ember holds an exclusive option to license these TRPV4 findings and technology.

28 Sep 2012

UNMCC to investigate R-ketorolac use against ovarian cancer cells

Most drugs take ten years-and frequently, more-to go from concept to FDA approval. One way to reduce this time investment is to look for already-approved drugs that could be put to new uses. And that's just what Angela Wandinger-Ness, PhD, UNM Professor of Pathology, and Laurie Hudson, PhD, UNM Professor of Pharmaceutical Sciences, have done.

28 Sep 2012

Inflammation News and Research

Patients with eye diseases can benefit from ArtCornea

Study reveals atomic-level structure of the human peptidase enzyme meprin β

Countering neuroinflammation is indeed a potential therapeutic strategy for Alzheimer's

Simple new test can monitor treatment of eosinophilic esophagitis

Modulating immune response to injury could accelerate regeneration of peripheral nerves

Rare study highlights anal cancer prognosis risks

LpxC-1 can effectively treat antibiotic-resistant infections

DFG-funded project to research into complex regional pain syndrome

Multiple sclerosis symptoms worse in those with low vitamin D levels

Eating apples might help keep the cardiologist away

Zinc deficiency mechanism associated with many health problems, aging

Omega-3 fatty acid supplements could slow key biological process linked to aging

Researchers identify how p110delta molecule controls the body's inflammatory responses

Researchers identify IL-27 molecule involved in counterbalancing the immune system attack

FDA approves Abbott’s HUMIRA to treat ulcerative colitis

Abbott receives FDA approval for Humira to treat ulcerative colitis

Cholesterol precursor suppresses inflammatory response genes, causes atherosclerosis

Researchers reduce life-threatening complication of stem cell transplants in mice with leukemia

Inhibiting TRPV4 protects against diet-induced obesity, inflammation and insulin resistance

UNMCC to investigate R-ketorolac use against ovarian cancer cells

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