Neuroscience News and Research

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Scientists detail role of TDP-43 in ALS pathology

Amyotrophic lateral sclerosis, known as ALS or more popularly, Lou Gehrig's disease, is a notorious neurodegenerative condition characterized by the progressive deterioration of brain and spinal cord neurons, resulting in the gradual but catastrophic loss of muscle control and ultimately, death.

5 Mar 2011

NorthShore receives $1.5 million gift to establish center for the study of complex diseases

NorthShore University HealthSystem (NorthShore) Foundation has received a $1.5 million gift for the creation of the Center for the Study of Complex Diseases. The development of the Center, which is being established within the NorthShore Research Institute, is made possible through a generous gift by Mr. and Mrs. Richard L. Keyser of Glencoe, Ill., through the Keyser Family Research Fund.

4 Mar 2011

European Commission approves BMY's ONGLYZA to treat type 2 diabetes

Bristol-Myers Squibb Company and AstraZeneca today announced that the European Commission has approved a label update for ONGLYZA in the treatment of adults with type 2 diabetes who have moderate or severe renal impairment. The approved dosage for the patient group is a new once-daily 2.5 mg dose.

4 Mar 2011

Few primary care physicians pay adequate attention to patients taking prescription opioid drugs

Few primary care physicians pay adequate attention to patients taking prescription opioid drugs — despite the potential for abuse, addiction and overdose, according to a new study by researchers at Albert Einstein College of Medicine of Yeshiva University.

4 Mar 2011

New study finds liver instead of the brain as source of Alzheimer’s plaques

Unexpected results from a Scripps Research Institute and ModGene, LLC study could completely alter scientists' ideas about Alzheimer's disease—pointing to the liver instead of the brain as the source of the "amyloid" that deposits as brain plaques associated with this devastating condition. The findings could offer a relatively simple approach for Alzheimer's prevention and treatment.

4 Mar 2011

New computer-controlled system to create cell assembly line

Borrowing a page from modern manufacturing, scientists from the Florida campus of The Scripps Research Institute have built a microscopic assembly line that mass produces synthetic cell-like compartments.

4 Mar 2011

Lactate plays critical role in formation of long-term memory

Researchers from Mount Sinai School of Medicine have found that lactate, a type of energy fuel in the brain, plays a critical role in the formation of long-term memory. These findings have important implications for common illnesses like Alzheimer's disease, other neurodegenerative disorders, aging-related memory impairment and diabetes. The research is published in the March 4th issue of the journal Cell.

4 Mar 2011

Efficiency of brain function depends on family's genetic makeup

How well our brain functions is largely based on our family's genetic makeup, according to a University of Melbourne led study.

4 Mar 2011

Eisai receives FDA approval for BANZEL Oral Suspension to treat seizures linked with LGS

Eisai Inc. today announced that the U.S. Food and Drug Administration has approved BANZEL Oral Suspension, 40 mg/mL, for the adjunctive treatment of seizures associated with Lennox-Gastaut syndrome in children 4 years and older and adults.

3 Mar 2011

Feet first? Old mitochondria might be responsible for neuropathy in the extremities

The burning, tingling pain of neuropathy may affect feet and hands before other body parts because the powerhouses of nerve cells that supply the extremities age and become dysfunctional as they complete the long journey to these areas, Johns Hopkins scientists suggest in a new study. The finding may eventually lead to new ways to fight neuropathy, a condition that often accompanies other diseases including HIV/AIDS, diabetes and circulatory disorders.

3 Mar 2011

Eisai announces publication of Halaven Phase III study results against breast cancer in The Lancet journal

Eisai announced today that results from the global Phase III clinical study "EMBRACE" will be published online in The Lancet.

3 Mar 2011

Study demonstrates neuronal loss during initial stages of HIV infection in mouse model

A new mouse model closely resembles how the human body reacts to early HIV infection and is shedding light on nerve cell damage related to the disease, according to researchers funded by the National Institutes of Health.

3 Mar 2011

Tobacco smoking leads to less activity in the 'executive center' of brain

Tobacco smoking is the leading preventable cause of death and disease in the U.S., with more than 400,000 deaths each year attributable to smoking or its consequences. And yet teens still smoke. Indeed, smoking usually begins in the teen years, and approximately 80 percent of adult smokers became hooked by the time they were 18. Meanwhile, teens who don't take up smoking usually never do.

3 Mar 2011

Ibuprofen may protect against development of Parkinson's disease

New research suggests that ibuprofen may offer protection against developing Parkinson's disease, according to one of the largest studies to date investigating the possible benefits of the over-the-counter drug on the disease. The study is published in the March 2, 2011, online issue of Neurology®, the medical journal of the American Academy of Neurology.

2 Mar 2011

Viruses that are natural part of human genome may retrovirus culprit

A retrovirus that inserted itself into the human genome thousands of years ago may be responsible for some cases of the neurodegenerative disease amyotrophic lateral sclerosis (ALS), also known as Lou Gherig’s disease. The finding, made by Johns Hopkins scientists, may eventually give researchers a new way to attack this universally fatal condition.

2 Mar 2011

UH Ahuja Medical Center officially opens its doors to patients on March 2

University Hospitals Ahuja Medical Center – the first new stand-alone hospital in Cuyahoga County in 30 years –officially opens its doors to patients on March 2.

2 Mar 2011

BRF funded projects generate over 8 times of the initial investment in additional funding

The Brain Research Foundation today announced that a recent analysis of its seed grant program indicates that BRF funded projects generate over 8 times the initial investment in additional funding. The findings were based on a sample of 47 projects over a three-year period that received $1.4 million in BRF funding and subsequently generated approximately $12 million in additional funding.

2 Mar 2011

Scientists discover signaling pathway in brain to induce cellular leptin resistance

Researchers at UT Southwestern Medical Center have identified a signaling pathway in the brain that's sufficient to induce cellular leptin resistance, a problem that decreases the body's ability to "hear" that it is full and should stop eating.

2 Mar 2011

Genetic switch increases blood vessels in skeletal muscle of non-exercising mice

Many people suffer from a devastating condition known as critical limb ischemia (CLI) that can lead to muscle wasting and even amputation. The disease is linked to the blockage of blood flow to the skeletal muscle and current treatment options include rehabilitative exercise and surgical bypass of blood vessels. New preclinical research suggests there may be a way to restore blood supply in skeletal muscle without traditional intervention.

2 Mar 2011

Experimental drug may help preserve neurological function in survivors of sudden cardiac arrest

An experimental drug that targets a brain system that controls inflammation might help preserve neurological function in people who survive sudden cardiac arrest, new research suggests.

2 Mar 2011

Neuroscience News and Research

Scientists detail role of TDP-43 in ALS pathology

NorthShore receives $1.5 million gift to establish center for the study of complex diseases

European Commission approves BMY's ONGLYZA to treat type 2 diabetes

Few primary care physicians pay adequate attention to patients taking prescription opioid drugs

New study finds liver instead of the brain as source of Alzheimer’s plaques

New computer-controlled system to create cell assembly line

Lactate plays critical role in formation of long-term memory

Efficiency of brain function depends on family's genetic makeup

Eisai receives FDA approval for BANZEL Oral Suspension to treat seizures linked with LGS

Feet first? Old mitochondria might be responsible for neuropathy in the extremities

Eisai announces publication of Halaven Phase III study results against breast cancer in The Lancet journal

Study demonstrates neuronal loss during initial stages of HIV infection in mouse model

Tobacco smoking leads to less activity in the 'executive center' of brain

Ibuprofen may protect against development of Parkinson's disease

Viruses that are natural part of human genome may retrovirus culprit

UH Ahuja Medical Center officially opens its doors to patients on March 2

BRF funded projects generate over 8 times of the initial investment in additional funding

Scientists discover signaling pathway in brain to induce cellular leptin resistance

Genetic switch increases blood vessels in skeletal muscle of non-exercising mice

Experimental drug may help preserve neurological function in survivors of sudden cardiac arrest

Event guide: 8th Neuroimmunology Drug Development Summit 2026 eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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