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OXGENE introduces SLIM platform for discovery of antibodies against membrane proteins

OXGENE™ announces the introduction of its self-labelling integral membrane (SLIM™) protein discovery system.

12 Jan 2021

Study investigates effect of anti-CD45 RIT lymphodepletion on immune cell types

Oncotarget recently published "Targeted lymphodepletion with a CD45-directed antibody radioconjugate as a novel conditioning regimen prior to adoptive cell therapy" which reported that Chimeric antigen receptor T cell therapies, and adoptive cell therapy in general, represent one of the most promising anti-cancer strategies.

12 Jan 2021

Insulin nanoparticles may become an alternative to insulin injections for diabetic patients

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed insulin nanoparticles that may one day become the basis for an oral medicine, and an alternative to insulin injections for diabetic patients.

12 Jan 2021

Researchers identify shorter form of ACE2 that lacks SARS-CoV-2 binding site

A shadow over the promising inhaled interferon beta COVID-19 therapy has been cleared with the discovery that although it appears to increase levels of ACE2 protein - coronavirus' key entry point into nose and lung cells - it predominantly increases levels of a short version of that protein, which the virus cannot bind to.

12 Jan 2021

Researchers study the behavior of regulatory T cells to understand periodontal disease

In diseases characterized by bone loss -such as periodontitis, rheumatoid arthritis, and osteoporosis- there is a lot that scientists still don't understand. What is the role of the immune response in the process? What happens to the regulatory mechanisms that protect bone?

12 Jan 2021

Scientists receive $3.4 million to study care options for patients with chest pain due to anxiety

Indiana University School of Medicine and Regenstrief Institute research scientists have received a $3.4 million award from the Patient-Centered Outcomes Research Institute to investigate the best care options for the 40 percent of people who go to the hospital emergency department with chest pain that is determined to be caused by anxiety rather than a cardiac event.

11 Jan 2021

Family history of suicide attempt linked to lower neurocognitive functioning in youth

hildren and adolescents with a family history of suicide attempts have lower executive functioning, shorter attention spans, and poorer language reasoning than those without a family history, according to a new study by researchers from the Lifespan Brain Institute of Children's Hospital of Philadelphia and the University of Pennsylvania.

11 Jan 2021

Polymer patch provides controlled release of drugs for post-operative pain management

A Duke-led team of scientists has developed a bio-compatible surgical patch that releases non-opioid painkillers directly to the site of a wound for days and then dissolves away.

11 Jan 2021

MDC researchers develop a potent weapon against lymphomas

MDC researchers have developed a new approach to CAR T-cell therapy. The team has shown in Nature Communications that the procedure is very effective, especially when it comes to fighting follicular lymphomas and chronic lymphocytic leukemia, the most common type of blood cancer in adults.

11 Jan 2021

Master Regulator proteins control cancer transcriptional identity

Thousands of different genetic mutations have been implicated in cancer, but a new analysis of almost 10,000 patients found that regardless of the cancer's origin, tumors could be stratified in only 112 subtypes and that, within each subtype, the Master Regulator proteins that control the cancer's transcriptional state were virtually identical, independent of the specific genetic mutations of each patient.

11 Jan 2021

Study finds association between severity of COVID-19 and shorter telomeres

Patients with severe COVID-19 disease have significantly shorter telomeres, according to a study conducted by researchers at the Spanish National Cancer Research Centre in collaboration with the COVID-IFEMA Field Hospital, published in the journal Aging.

11 Jan 2021

Study shows how intestinal stem cells constantly renew and give rise to specialized cell types

The gut plays a central role in the regulation of the body's metabolism and its dysfunction is associated with a variety of diseases, such as obesity, diabetes, colitis and colorectal cancer that affect millions of people worldwide.

11 Jan 2021

Gene therapy can effectively treat mice with tuberous sclerosis complex, shows study

Patients with tuberous sclerosis complex, a genetic disorder characterized by the growth of noncancerous tumors in multiple organs of the body, have limited treatment options.

8 Jan 2021

Study: Many patients want virtual mental health care even after the pandemic subsides

A year ago, trying to find patients who would agree to see their University of Michigan mental health provider through a video screen felt like pulling teeth.

8 Jan 2021

New approach to tame botulinum toxin for drug delivery

While rare, botulism can cause paralysis and is potentially fatal. It is caused by nerve-damaging toxins produced by Clostridium botulinum -- the most potent toxins known.

8 Jan 2021

Multiple withdrawal symptoms experienced by people using medical marijuana for chronic pain

More than half of people who use medical marijuana products to ease pain also experience clusters of multiple withdrawal symptoms when they're between uses, a new study finds.

8 Jan 2021

New insights into ferroptosis resistance of cancer cells

Announcing a new publication for BIO Integration journal. In this opinion article the authors Daiyun Xu, Yonghui Lü, Yongxiao Li, Shengbin Li, Zhe Wang and Junqing Wang from Sun Yat-Sen University, Guangzhou, China discuss ferroptosis resistance in cancer.

8 Jan 2021

Therapy News and Research

OXGENE introduces SLIM platform for discovery of antibodies against membrane proteins

Study investigates effect of anti-CD45 RIT lymphodepletion on immune cell types

Insulin nanoparticles may become an alternative to insulin injections for diabetic patients

Researchers identify shorter form of ACE2 that lacks SARS-CoV-2 binding site

Researchers study the behavior of regulatory T cells to understand periodontal disease

Scientists receive $3.4 million to study care options for patients with chest pain due to anxiety

Family history of suicide attempt linked to lower neurocognitive functioning in youth

Polymer patch provides controlled release of drugs for post-operative pain management

MDC researchers develop a potent weapon against lymphomas

Master Regulator proteins control cancer transcriptional identity

Study finds association between severity of COVID-19 and shorter telomeres

Study shows how intestinal stem cells constantly renew and give rise to specialized cell types

Gene therapy can effectively treat mice with tuberous sclerosis complex, shows study

Study: Many patients want virtual mental health care even after the pandemic subsides

New approach to tame botulinum toxin for drug delivery

Multiple withdrawal symptoms experienced by people using medical marijuana for chronic pain

New insights into ferroptosis resistance of cancer cells

Study reveals six-month consequences of COVID-19 in patients discharged from hospital

UCSF researchers discover a new way to control immune system's 'natural killer' cells

Proteogenomics can help determine effective treatment for head and neck squamous cell carcinoma

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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