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Cedars-Sinai researchers explore whether healthy lifestyle choices can slow or prevent Alzheimer's disease

Cedars-Sinai neuroscience researchers are studying whether extensive changes in lifestyle among patients with mild cognitive impairment can slow the progression of Alzheimer's disease.

13 May 2016

New research solves mystery of why cetuximab drug proved futile for many colorectal cancer patients

Cancer researchers have identified a marker that shows up in a blood test that determines which patients with colorectal cancer that has spread would benefit from receiving the drug cetuximab.

13 May 2016

Inhibiting autophagy can effectively block tumor cell migration, breast cancer metastasis

Researchers from the University of Chicago have shown that inhibiting autophagy, a self-devouring process used by cells to degrade large intra-cellular cargo, effectively blocks tumor cell migration and breast cancer metastasis in tumor models.

13 May 2016

Genetic change to non-DNA structures in cell can cause cancer

A mutation that affects the proteins that package DNA--without changing the DNA itself--can cause a rare form of cancer, according to new findings in this week's Science from researchers at The Rockefeller University.

13 May 2016

Histone mutation linked to fatal pediatric brain tumor

A single defect in a gene that codes for a histone — a "spool" that wraps idle DNA — is linked to pediatric cancers in a study published today in the journal Science.

13 May 2016

Vessel-sparing radiation, better understanding of prostate anatomy can improve quality of life

Remember the game Operation? You need to carefully remove the body part without nicking the sides or the buzzer will sound.

12 May 2016

Novel UBC-developed device could soon pave way for improved cancer diagnosis

A new UBC-developed method to isolate cancer cells that have escaped from a tumour could soon pave the way for improved diagnosis and treatment.

12 May 2016

Comprehensive genomic characterizations of ACC provide potentially better treatment options

An international team of scientists, including those at the Translational Genomic Research Institute (TGen), have discovered new avenues of potential treatments for a rare and deadly cancer known as Adrenocortical Carcinoma, or ACC.

11 May 2016

Scientists discover reliable marker to spot CAFs in oral cancer tissues

For the first time, researchers have identified a reliable marker (PDGFRβ) to detect carcinoma-associated fibroblasts (cells within the tumor that encourage growth and metastasis) (CAFs) in oral cancer tissues. With this discovery, anti-PDGFRβ treatment could soon be combined with existing tumor treatments to provide a more effective cancer therapy.

11 May 2016

Jumping genes may play crucial role in generation of cancer

For more than 50 years, scientists have known of the existence of "jumping genes," strands of DNA material that can move from one location in the genome to another.

11 May 2016

New interactive radiation therapy planning system can help improve patient's chances of recovery

Radiation therapy is one of the most essential elements in cancer treatment. But properly planning radiation therapy is a highly complex task. Fraunhofer mathematicians have joined an alliance with medical physicists and physicians to improve the therapy planning process. In doing so they have helped improve patient's chances of recovery.

11 May 2016

Robotic VATS could be safe alternative to conventional thoracoscopic procedures for lung cancer treatment

A new study shows that robotic video-assisted lung resection to remove a tumor achieves comparable outcomes with no significant differences in complications compared to conventional video-assisted thoracoscopic surgery (VATS), and robotic VATS (RVATS) may allow for preservation of more healthy lung tissue.

11 May 2016

Patient-specific immunotherapeutic vaccines may improve overall survival of melanoma patients

Two patients with melanoma that had spread to the liver survived for at least 8.5 and 12 years after resection of the hepatic tumor and treatment with patient-specific immunotherapeutic vaccines.

11 May 2016

Genetic variations that increase PKC alpha activity may influence development of Alzheimer's disease

In Alzheimer's disease, plaques of amyloid beta protein accumulate in the brain, damaging connections between neurons.

11 May 2016

Simultaneous DNA, RNA and protein analysis to enhance cancer immunology studies: an interview with Dr Joseph Beechem

Cancer immunology is all about how your immune cells are going to fight and kill your tumor cells. If you look at the pure genetic code of a T-cell that's going to kill your tumor compared to the same cell that has been “put-to-sleep” (by the tumor), the pure genetic DNA content of those two cells are identical.

From NanoString Technologies 11 May 2016

Sophisticated technology helps model and simulate optimal dose for pediatric ependymoma patients

St. Jude Children's Research Hospital scientists have used sophisticated pharmacologic modeling and simulation to translate preclinical findings into a successful phase I clinical trial of a chemotherapy agent for treatment of ependymoma. The research marked the first time the approach has been used to calculate drug doses for a clinical trial in pediatric brain tumor patients.

10 May 2016

Study highlights role of specific chromosomal deletion in cancer development, progression

In a typical cancer cell, up to one-quarter of the genome is lost due to large chromosomal deletions, while the concomitant loss of hundreds of genes creates vulnerabilities that are impossible to reveal through the study of individual genes. Prof. Anna Sablina and her team at VIB/KU Leuven optimized a workflow for the generation of cell lines with targeted chromosomal deletions.

10 May 2016

Study links lower concentration of heat-shock proteins to recurrence of thymic tumors

In most cases, tumors of the thymus gland are removed by surgical resection. However, they recur after a few years in up to one third of patients. A research team headed up by thoracic surgeon Bernhard Moser of the Thoracic Surgery Department at MedUni Vienna has successfully demonstrated that these tumors form heat-shock proteins. The lower the concentration of these proteins, the more quickly tumors recur. The study has been published in the leading journal Scientific Reports.

10 May 2016

Ga-68 DOTATATE PET/CT scans more effective than current imaging standard for detecting NETS

A recent study reported in the May issue of the Journal of Nuclear Medicine demonstrates that Ga-68 DOTATATE PET/CT scans are superior to In-111 pentetreotide scans, the current imaging standard in the United States for detecting neuroendocrine tumors, and could significantly impact treatment management.

10 May 2016

MUSC Hollings Cancer Center receives $8.9 million grant to explore signaling in sphingolipids

The Medical University of South Carolina's Hollings Cancer Center received an $8.9 million grant from the National Cancer Institute designed to foster collaboration across clinical and laboratory research for the study of signaling in sphingolipids, a class of lipids known to be involved in the growth of solid tumor cancers.

10 May 2016

Tumor News and Research

Cedars-Sinai researchers explore whether healthy lifestyle choices can slow or prevent Alzheimer's disease

New research solves mystery of why cetuximab drug proved futile for many colorectal cancer patients

Inhibiting autophagy can effectively block tumor cell migration, breast cancer metastasis

Genetic change to non-DNA structures in cell can cause cancer

Histone mutation linked to fatal pediatric brain tumor

Vessel-sparing radiation, better understanding of prostate anatomy can improve quality of life

Novel UBC-developed device could soon pave way for improved cancer diagnosis

Comprehensive genomic characterizations of ACC provide potentially better treatment options

Scientists discover reliable marker to spot CAFs in oral cancer tissues

Jumping genes may play crucial role in generation of cancer

New interactive radiation therapy planning system can help improve patient's chances of recovery

Robotic VATS could be safe alternative to conventional thoracoscopic procedures for lung cancer treatment

Patient-specific immunotherapeutic vaccines may improve overall survival of melanoma patients

Genetic variations that increase PKC alpha activity may influence development of Alzheimer's disease

Simultaneous DNA, RNA and protein analysis to enhance cancer immunology studies: an interview with Dr Joseph Beechem

Sophisticated technology helps model and simulate optimal dose for pediatric ependymoma patients

Study highlights role of specific chromosomal deletion in cancer development, progression

Study links lower concentration of heat-shock proteins to recurrence of thymic tumors

Ga-68 DOTATATE PET/CT scans more effective than current imaging standard for detecting NETS

MUSC Hollings Cancer Center receives $8.9 million grant to explore signaling in sphingolipids

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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