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Portuguese scientists identify a molecular mechanism that can lead to metastases in breast cancers

Portuguese scientists identified a molecular mechanism that can lead to metastases (spread of the cancer from the original site to other remote parts of the body) in breast cancers. Abnormally high levels of P-cadherin - an adhesion molecule that enables cells to bind together - occur in about a third of all breast cancers and are associated with poor prognosis.

1 Dec 2009

Researchers devise a way to deliver right therapy directly to tumors using aptamers

Finding and treating a tumor without disturbing normal tissue presents challenges - sometimes the most effective therapies can be invasive and harsh.

1 Dec 2009

Drinking sugar-sweetened cola a week prior to pregnancy elevates diabetes during pregnancy

Researchers from LSU Health Sciences Center New Orleans School of Public Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Harvard School of Public Health, Brigham and Women's Hospital, and Harvard Medical School, have found for the first time that drinking more than 5 servings of sugar- sweetened cola a week prior to pregnancy appears to significantly elevate the risk of developing diabetes during pregnancy.

1 Dec 2009

Clinical interventions may help cocaine abusers from using drugs and prevent relapse

When asked to inhibit their response to a "cocaine-cues" video, active cocaine abusers were, on average, able to suppress activity in brain regions linked to drug craving, according to a new study at the U.S. Department of Energy's Brookhaven National Laboratory. The results, to be published in an upcoming issue of NeuroImage, suggest that clinical interventions designed to strengthen these inhibitory responses could help cocaine abusers stop using drugs and avoid relapse.

30 Nov 2009

Bantam miRNA linked to the circadian clock

How does our biological system know that it is supposed to operate on a 24-hour cycle? Scientists at the Hebrew University of Jerusalem have discovered that a tiny molecule holds the clue to the mystery.

30 Nov 2009

ALS research collaboration receives philanthropic funding

Three prominent philanthropic organizations – The Angel Fund, The ALS Therapy Alliance and Project ALS -- dedicated to finding a treatment for amyotrophic lateral sclerosis (ALS) have financed a new collaboration between one of the world’s leading ALS researchers and RXi Pharmaceuticals Corporation, a biopharmaceutical company pursuing the development and commercialization of proprietary therapeutics based on RNA interference (RNAi).

30 Nov 2009

Copper sequestering drug tetrathiomolybdate shown to be effective in treating Wilson disease

The copper sequestering drug tetrathiomolybdate (TM) has been shown in studies to be effective in the treatment of Wilson disease, a disease caused by an overload of copper, and certain metastatic cancers.

27 Nov 2009

Breast Cancer Campaign awards a three year project grant to Cambridge scientist

Individualised treatment for each breast cancer patient could soon become a reality, according to Breast Cancer Campaign.

26 Nov 2009

Three high risk indicators that aid mammography screening

Mammography Reporting System, Inc. (MRS) will demonstrate their newest high risk indicator at RSNA 2009, in Chicago. MRS is the only company in the industry offering three separate high risk indicators to alert radiologists of potentially at-risk patients at the very point they interpret a mammogram.

26 Nov 2009

Findings show the relationship between neurotransmitter dopamine and ADHD

Scientists at the California Institute of Technology (Caltech) have uncovered evidence of a primitive emotion-like behavior in the fruit fly, Drosophila melanogaster.

26 Nov 2009

Tips for making holiday celebrations comfortable and enjoyable for people with hearing loss

For many of the millions of hearing impaired Americans, especially the 27 million living with untreated hearing loss, the holidays may not be all that happy, says audiologist Cindy Beyer.

25 Nov 2009

Study reveals that ghrelin can increase resistance to Parkinson's disease

Ghrelin, a hormone produced in the stomach, may be used to boost resistance to, or slow, the development of Parkinson's disease, Yale School of Medicine researchers report in a study published in a recent issue of the Journal of Neuroscience.

25 Nov 2009

Researchers uncover atomic-level action of ring-shaped protein motors

The atomic-level action of a remarkable class of ring-shaped protein motors has been uncovered by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) using a state-of-the-art protein crystallography beamline at the Advanced Light Source (ALS).

25 Nov 2009

Faulty enzyme may contribute to malignant brain tumour formation

Around 70 per cent of people with a type of brain tumour - called a low-grade glioma - have a faulty version of an enzyme called IDH1. The mutation is also found in a significant proportion of patients with acute myeloid leukaemia.

25 Nov 2009

Vitamin D deficiency may increase risk of stroke, heart disease and death, finds study

While mothers have known that feeding their kids milk builds strong bones, a new study by researchers at the Heart Institute at Intermountain Medical Center in Salt Lake City suggests that Vitamin D contributes to a strong and healthy heart as well - and that inadequate levels of the vitamin may significantly increase a person's risk of stroke, heart disease, and death, even among people who've never had heart disease.

24 Nov 2009

Exposure to environmental pollutants is associated with asthma symptoms in children

Exposure shortly after birth to ambient metals from residential heating oil combustion and particles from diesel emissions are associated with respiratory symptoms in young inner city children, according to a new study by researchers at the Columbia Center for Children's Environmental Health (CCCEH) at Columbia University's Mailman School of Public Health.

24 Nov 2009

Custom Spine launches two new innovative spine systems at NASS annual meeting

Custom Spine, a company dedicated to offering advanced spinal solutions, launched two new innovative spine systems at the North American Spine Society's (NASS) annual meeting being held in San Francisco.

24 Nov 2009

DTCA linked with increased Medicaid pharmacy expenditures

Direct-to-consumer advertising (DTCA) for a commonly prescribed antiplatelet drug does not appear associated with increased use, but may be associated with increased drug costs and Medicaid pharmacy expenditures, according to a report in the November 23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

24 Nov 2009

Vitamin D: A multi-purpose nutrient for overall health

A string of recent discoveries about the multiple health benefits of vitamin D has renewed interest in this multi-purpose nutrient, increased awareness of the huge numbers of people who are deficient in it, spurred research and even led to an appreciation of it as "nature's antibiotic."

24 Nov 2009

Mutated IDH1 gene linked to the progression of gliomas

Agios Pharmaceuticals today announced that its scientists have established, for the first time, that the mutated IDH1 gene has a novel enzyme activity consistent with a cancer-causing gene, or oncogene.

23 Nov 2009

X linked News and Research

Portuguese scientists identify a molecular mechanism that can lead to metastases in breast cancers

Researchers devise a way to deliver right therapy directly to tumors using aptamers

Drinking sugar-sweetened cola a week prior to pregnancy elevates diabetes during pregnancy

Clinical interventions may help cocaine abusers from using drugs and prevent relapse

Bantam miRNA linked to the circadian clock

ALS research collaboration receives philanthropic funding

Copper sequestering drug tetrathiomolybdate shown to be effective in treating Wilson disease

Breast Cancer Campaign awards a three year project grant to Cambridge scientist

Three high risk indicators that aid mammography screening

Findings show the relationship between neurotransmitter dopamine and ADHD

Tips for making holiday celebrations comfortable and enjoyable for people with hearing loss

Study reveals that ghrelin can increase resistance to Parkinson's disease

Researchers uncover atomic-level action of ring-shaped protein motors

Faulty enzyme may contribute to malignant brain tumour formation

Vitamin D deficiency may increase risk of stroke, heart disease and death, finds study

Exposure to environmental pollutants is associated with asthma symptoms in children

Custom Spine launches two new innovative spine systems at NASS annual meeting

DTCA linked with increased Medicaid pharmacy expenditures

Vitamin D: A multi-purpose nutrient for overall health

Mutated IDH1 gene linked to the progression of gliomas

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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