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Understanding structure of HIV-1 protease vital to development of next-generation HIV drugs

HIV, the virus that causes AIDS, has become one of the world’s most serious health and development challenges.

24 May 2016

Researchers explore phenomenon that causes late mortality in sepsis patients

It's known that many patients die in the months and years after sepsis. But no one has known if this increased risk of death (in the 30 days to 2 years after sepsis) is because of sepsis itself, or because of the pre-existing health conditions the patient had before acquiring the complication.

24 May 2016

Small lipid nanocarrier may deliver chemotherapeutic drug more efficiently to brain tumor cells

Great discoveries do come in small packages. Few know that better than Ann-Marie Broome, Ph.D., who feels nanotechnology holds the future of medicine with its ability to deliver powerful drugs in tiny, designer packages.

23 May 2016

Nine creative ways to improve cognitive development of children in developing countries

Grand Challenges Canada, funded by the Government of Canada, and the "Saving Brains" partners today announced investments in nine creative ways to protect and nurture the cognitive development of children in developing countries.

23 May 2016

Low-salt diets may increase CVD risk and death compared to average salt consumption

A large worldwide study has found that, contrary to popular thought, low-salt diets may not be beneficial and may actually increase the risk of cardiovascular disease (CVD) and death compared to average salt consumption.

23 May 2016

Cardioprotective effect proposed for metformin

A large retrospective analysis suggests that metformin could be cardioprotective in insulin-dependent patients with Type 2 diabetes.

21 May 2016

SPRINT supports stringent BP goals for elderly

Analysis of SPRINT participants older than 75 years shows that they too benefitted from an intensive blood pressure target of 120 mmHg.

20 May 2016

Children treated at stand-alone Level I PTC have better outcomes following motor vehicle accident

Children and adolescents injured in motor vehicle accidents have better outcomes when treated at a stand-alone Level I pediatric trauma center (PTC) than at general adult trauma centers (ATC) or adult trauma centers with added Level I pediatric qualifications (ATC+PTC), according to a new study to be published in the Journal of Pediatric Surgery by researchers from Children's Minnesota.

20 May 2016

ITM researchers develop small, user-friendly device for real time detection of arrhythmias

Researchers at the Technological Institute of Morelia in Mexico, created a device for detecting cardiac arrhythmias in real time, and that turns portable a system that uses electrodes placed on the chest of the patient or as part of clothing (shirt), plus it allows to alert the physician at the same time there is an irregularity in the heartbeat.

20 May 2016

Simple sarcopenia screening method could easily diagnose severity of heart disease

Researchers from Kumamoto University in Japan have shown that a simple screening method could quickly and easily diagnose the severity of heart disease. The method was originally developed to diagnose sarcopenia, a disease that causes a loss of muscle mass and strength.

19 May 2016

AKR1C3 enzyme could be promising therapeutic target for managing CRPC, AML

Prostate cancer is the second leading cause of mortality among American men with the highest incidence rate of all cancers reported in the U.S. Male sex hormones testosterone (T) and 5α-dihydrotestosterone (5α-DHT) promote prostate cancer progression.

19 May 2016

MERS individuals develop severe critical illness, higher mortality than non-MERS SARI patients

Patients with Middle East Respiratory Syndrome (MERS) develop more severe critical illness and have higher mortality than patients with non-MERS severe acute respiratory infection (SARI), according to investigators involved with the largest study of critically ill patients with MERS.

19 May 2016

USP14 enzyme could be promising biomarker for detecting risk of endometrial cancer recurrences

Endometrial cancer is the most common gynecologic cancer in the U.S. Most cases are diagnosed at early stage and have good prognosis. Unfortunately, some patients with early stage and low grade endometrial cancer experience recurrence - and the reasons are not entirely clear.

19 May 2016

Strategy choice impacts long-term mortality in bifurcation stenting

Using a provisional rather than a planned two-stent strategy for coronary bifurcation stenting may halve long-term mortality, pooled study data show.

19 May 2016

Research sheds light on potential impact of HCV treatment in preventing virus transmission

An international team of researchers has shed light on the potential impact of new drugs for hepatitis C virus (HCV).

19 May 2016

YouGov survey: More than one in four UK employees concerned about working with colleague with epilepsy

Over a quarter (26%) of workers in Great Britain would be concerned about working with a colleague with epilepsy, according to a new nationwide YouGov survey of over 2,000 people.

18 May 2016

Overnight extubations in ICU patients linked to higher mortality

Adult patients who were admitted to U.S. intensive care units had higher mortality if they were extubated overnight. The results reported at the ATS 2016 International Conference may discourage hospital administrators from expanding the practice of overnight extubations in ICUs, which the lead author noted are rapidly being transformed to provide continuity of care.

18 May 2016

Comprehensive outlook of COPD care in the U.S.

Fifteen million: That's the number of adults in the United States affected by chronic obstructive pulmonary disease, or COPD.

18 May 2016

Philips leads large scale eHealth initiative to deliver coordinated care for tens of thousands of chronic disease patients across Europe

Royal Philips and a consortium of leading European healthcare regions, companies, universities and hospitals* today announced the start of the first large scale care coordination and telehealth program in the European Union to support tens of thousands of people living with chronic conditions.

18 May 2016

Automated process uses EMR to identify patients with potential for clinical deterioration

Hospitalized patients can deteriorate quickly, requiring prompt identification and treatment, especially since each hour of treatment delay can increase the risk of mortality.

17 May 2016

Mortality News and Research

Understanding structure of HIV-1 protease vital to development of next-generation HIV drugs

Researchers explore phenomenon that causes late mortality in sepsis patients

Small lipid nanocarrier may deliver chemotherapeutic drug more efficiently to brain tumor cells

Nine creative ways to improve cognitive development of children in developing countries

Low-salt diets may increase CVD risk and death compared to average salt consumption

Cardioprotective effect proposed for metformin

SPRINT supports stringent BP goals for elderly

Children treated at stand-alone Level I PTC have better outcomes following motor vehicle accident

ITM researchers develop small, user-friendly device for real time detection of arrhythmias

Simple sarcopenia screening method could easily diagnose severity of heart disease

AKR1C3 enzyme could be promising therapeutic target for managing CRPC, AML

MERS individuals develop severe critical illness, higher mortality than non-MERS SARI patients

USP14 enzyme could be promising biomarker for detecting risk of endometrial cancer recurrences

Strategy choice impacts long-term mortality in bifurcation stenting

Research sheds light on potential impact of HCV treatment in preventing virus transmission

YouGov survey: More than one in four UK employees concerned about working with colleague with epilepsy

Overnight extubations in ICU patients linked to higher mortality

Comprehensive outlook of COPD care in the U.S.

Philips leads large scale eHealth initiative to deliver coordinated care for tens of thousands of chronic disease patients across Europe

Automated process uses EMR to identify patients with potential for clinical deterioration

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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