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Discovery suggests a new way to treat spinal muscular atrophy

Columbia researchers have discovered how a genetic defect leads to spinal muscular atrophy (SMA), a critical piece of information about the disease that neurologists have been seeking for decades.

23 Mar 2023

New discovery could help target the causes of aging and cancer development

A protein complex prevents the repair of genome damage in human cells, in mice and in the nematode Caenorhabditis elegans, a team of researchers at the University of Cologne has discovered.

23 Mar 2023

Modulating the function of immune cells to recover aging muscle's regenerative capacity

Muscle is able to regenerate through a process that involves multiple steps and players, including the immune system.

23 Mar 2023

New way to safely, sustainably synthesize a molecule with remarkable anticancer properties

Plants produce all types of curious chemicals. Some deter predators. Some smell wonderful. Some even have medicinal value.

23 Mar 2023

Study provides evidence for a strong role of autophagy in controlling intracellular infections

Researchers at the Francis Crick Institute have found that the body's process of removing old and damaged cell parts, is also an essential part of tackling infections that take hold within our cells, like TB.

23 Mar 2023

Inhibition of cell wall formation arrests staphylococcal cell division

We still do not understand exactly how antibiotics kill bacteria. However, this understanding is necessary if we want to develop new antibiotics.

23 Mar 2023

Study outlines a meta-scale approach to quantifying the human proteome

A major puzzle of biology is that while the human genome contains roughly 20,000 genes, many comparatively primitive organisms - including the universally-studied worm C. elegans - have almost the same number of genes.

23 Mar 2023

Molecular mechanism involved in the development of type 2 diabetes discovered

Type 2 diabetes is a chronic disease in which the body does not produce enough insulin, or does not use it efficiently.

23 Mar 2023

Candidate hepatitis C mRNA vaccine induces protective immunity in animal model

In a recent study published in the npj vaccines journal, researchers assessed the immune protection elicited by messenger ribonucleic acid (mRNA) vaccines delivering Hepatitis C virus (HCV) E1 and modified E2.

23 Mar 2023

Understanding the structure of CFTR could help design more effective therapies for cystic fibrosis

Scientists at St. Jude Children's Research Hospital and Rockefeller University have combined their expertise to gain a better understanding of the cystic fibrosis transmembrane conductance regulator (CFTR).

23 Mar 2023

Golden spice commonly found in curry could enhance ovarian cancer treatments

A pharmacology researcher at New York Institute of Technology College of Osteopathic Medicine (NYITCOM) has co-authored a new study that makes a strong case for why a golden spice commonly found in curry could enhance ovarian cancer treatments.

23 Mar 2023

Study discovers a protein controlling resistance to chemotherapy

Despite the recent development of new targeted therapies, chemotherapies remain the most frequently used treatment to treat patients suffering from advanced cancers.

22 Mar 2023

SARS-CoV-2 infection damages CD8+ T cell response

In a recent study published in the journal Immunity, a team of researchers from the United States found that previous severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections reduce the activation and expansion of CD8+ T cells in response to coronavirus disease 2019 (COVID-19) vaccinations.

22 Mar 2023

Researchers identify an enzyme associated with kidney fibrosis in both mice and humans

Researchers at Nagoya University in Japan have identified two enzymes that are involved in macrophage polarization, one of the key factors affecting fibrosis.

22 Mar 2023

Researchers discover how a single mechanosensitive protein induces fibrosis

Researchers from Kyushu University have found how a single mechanosensitive protein induces the process that thickens and scars tissue, known as fibrosis. The protein, called VGLL3, was shown to contribute to fibrosis in multiple organs.

22 Mar 2023

Novel subset of memory B cells predicts long-lived antibody responses to influenza vaccination

Memory B cells play a critical role to provide long-term immunity after a vaccination or infection. In a study published in the journal Immunity, researchers describe a distinct and novel subset of memory B cells that predict long-lived antibody responses to influenza vaccination in humans.

22 Mar 2023

Animal studies show potential of new drug to curb painful hyperinflammation from osteoarthritis

A team of researchers at the Keck School of Medicine of USC have found a drug with the potential for curbing painful hyperinflammation from osteoarthritis, according to results of an animal study.

22 Mar 2023

Researchers discover how a mutation in the desmosomal gene leads to arrhythmogenic cardiomyopathy

Mutations in genes that form the desmosome are the most common cause of the cardiac disease arrhythmogenic cardiomyopathy (ACM), which affects one in 2000 to 5000 people worldwide.

22 Mar 2023

Naturally-occurring compound found in trees effective in fighting superbugs

Researchers at the University of Portsmouth have discovered that a naturally-occurring compound found in trees is effective in combating superbugs.

22 Mar 2023

High-fat and high-sugar foods can rewire the brain

Chocolate bars, crisps and fries - why can't we just ignore them in the supermarket? Researchers at the Max Planck Institute for Metabolism Research in Cologne, in collaboration with Yale University, have now shown that foods with a high fat and sugar content change our brain: If we regularly eat even small amounts of them, the brain learns to consume precisely these foods in the future.

22 Mar 2023

Cell News and Research

Discovery suggests a new way to treat spinal muscular atrophy

New discovery could help target the causes of aging and cancer development

Modulating the function of immune cells to recover aging muscle's regenerative capacity

New way to safely, sustainably synthesize a molecule with remarkable anticancer properties

Study provides evidence for a strong role of autophagy in controlling intracellular infections

Inhibition of cell wall formation arrests staphylococcal cell division

Study outlines a meta-scale approach to quantifying the human proteome

Molecular mechanism involved in the development of type 2 diabetes discovered

Candidate hepatitis C mRNA vaccine induces protective immunity in animal model

Understanding the structure of CFTR could help design more effective therapies for cystic fibrosis

Golden spice commonly found in curry could enhance ovarian cancer treatments

Study discovers a protein controlling resistance to chemotherapy

SARS-CoV-2 infection damages CD8+ T cell response

Researchers identify an enzyme associated with kidney fibrosis in both mice and humans

Researchers discover how a single mechanosensitive protein induces fibrosis

Novel subset of memory B cells predicts long-lived antibody responses to influenza vaccination

Animal studies show potential of new drug to curb painful hyperinflammation from osteoarthritis

Researchers discover how a mutation in the desmosomal gene leads to arrhythmogenic cardiomyopathy

Naturally-occurring compound found in trees effective in fighting superbugs

High-fat and high-sugar foods can rewire the brain

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