Heart News and Research

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Pitt team receives NIH award to optimize tissue-engineered vascular graft design

Just as a climbing plant needs the right trellis to thrive, a small-diameter tissue-engineered vascular graft (TEVG) needs the right scaffold to transform seeded cells into a native-like artery that can save a life.

25 Sep 2020

New drug offers hope for young boys with Duchenne muscular dystrophy

A new drug offers hope for young boys with the progressive neuromuscular disease Duchenne muscular dystrophy (DMD) by potentially offering an alternative to high-dose glucocorticoids that have significant side effects.

25 Sep 2020

University of Minnesota receives funding to initiate research on diabetes drug as a COVID-19 treatment

University of Minnesota Medical School researchers received funding from the Parsemus Foundation to initiate research on the widely-used diabetes medication, metformin, available globally as an inexpensive generic drug for prevention and treatment for COVID-19.

25 Sep 2020

FDA approves first drug for patients with hypereosinophilic syndrome in nearly 14 years

Today, the U.S. Food and Drug Administration approved Nucala (mepolizumab) for adults and children aged 12 years and older with hypereosinophilic syndrome (HES) for six months or longer without another identifiable non-blood related cause of the disease.

25 Sep 2020

Novel technique helps detect heart damage in top-level competition dogs

Frequent high-intensity exercise entails cardiac remodelling both in humans and animals. In dogs, especially those used for top-level competition, it is of great interest to learn whether they develop the so-called athletic heart syndrome.

25 Sep 2020

Social inequities in Black and South Asian immigrants increase risk of severe COVID-19 infection

Black, South Asian and Aboriginal populations from disadvantaged socioeconomic backgrounds in Canada are nearly four times more likely to have three or more medical conditions that have been identified as risk factors for severe illness from COVID-19.

25 Sep 2020

Study assesses cardiovascular and renal outcomes for ertugliflozin in patients with type 2 diabetes

A new study led by a cardiologist from Brigham and Women's Hospital has assessed the cardiovascular and renal outcomes for ertugliflozin, an SGLT2 inhibitor prescribed for patients with type 2 diabetes to help them control blood sugar levels

25 Sep 2020

Study highlights the importance of healthy placental development in pregnancy

The first stages of placental development take place days before the embryo starts to form in human pregnancies. The finding highlights the importance of healthy placental development in pregnancy, and could lead to future improvements in fertility treatments such as IVF, and a better understanding of placental-related diseases in pregnancy.

25 Sep 2020

Individuals with severe forms of COVID-19 disease can have compromised type I interferon responses

Individuals with severe forms of COVID-19 disease can present with compromised type I interferon (IFN) responses based on their genetics, according to results published in two papers today in the journal Science.

25 Sep 2020

Scientists develop single-cell atlas of the normal human heart

Scientists have for the first time documenting all of the different cell types and genes expressed in the healthy human heart, in new research published in the journal Nature.

25 Sep 2020

Scientists create first atlas of human heart cells

Ka-thump. Ka-thump. Ka-thump. Though we barely notice it most of the time, the steady beating of a human heart is an amazingly complex performance. Like an orchestra, thousands of cells have to master their individual performances as well as work together.

25 Sep 2020

Berlin researchers are pursuing the development of passive vaccination

Researchers at the German Center for Neurodegenerative Diseases (DZNE) and Charité - Universitätsmedizin Berlin have identified highly effective antibodies against the coronavirus SARS-CoV-2 and are now pursuing the development of a passive vaccination.

25 Sep 2020

New $1.5 million, multi-state data project to examine COVID-19 outcomes and treatments

The power of data, often an underappreciated catalyst to fixing the world's pressing problems, was recognized by Dr. Sally Hodder as a critical key in battling COVID-19 before West Virginia even reported its first case.

24 Sep 2020

NIA grant supports research on lifespan behavioral development and cognitive aging

The National Institute on Aging, or NIA, has awarded psychologists Chandra A. Reynolds of the University of California, Riverside, and Sally J. Wadsworth of the University of Colorado-Boulder a grant of more than $11 million to continue studying lifespan behavioral development and cognitive aging as individuals transition to mid-adulthood.

24 Sep 2020

Cellular and molecular map of the human heart could guide personalized medicine

Scientists have created a cellular and molecular map of the healthy human heart, to understand how this vital organ functions, and to shed light on what goes wrong in cardiovascular disease.

24 Sep 2020

Parental skin-to-skin contact dampens pain responses in newborn baby's brain

Being held by a parent with skin-to-skin contact reduces how strongly a newborn baby's brain responds to a painful medical jab, finds a new study led by researchers at UCL and York University, Canada.

24 Sep 2020

California expands privacy protection to public health workers amid threats

California will allow public health officials to participate in a program to keep their home addresses confidential, a protection previously reserved for victims of violence, abuse and stalking and reproductive health care workers.

24 Sep 2020

Stroke alarm clock may simplify and expedite time-sensitive acute stroke care

A digital clock that sounds alarms signaling each step of acute stroke care at the hospital is a low cost tool that helped doctors in Germany streamline and accelerate the time-sensitive process, according to new research published today in Stroke, a journal of the American Stroke Association, a division of the American Heart Association.

24 Sep 2020

AI used to define the cytokine storm implicated in fatal COVID-19

A new study published on the preprint server bioRxiv* in September 2020 reports the use of artificial intelligence (AI) to identify an invariant or universal host immune response found in all viral pandemics so far. The association of this response with severe COVID-19 phenotypes indicates a new understanding of the human immune response in viral pandemics.

24 Sep 2020

Gruthan Bioscience to develop new class of cholesterol-lowering drugs

Gruthan Bioscience, LLC, a Medical University of South Carolina startup based in Charleston, South Carolina, received a Small Business technology Transfer (STTR) award from the National Heart, Blood and Lung Institute in August to take the next step in developing a novel class of cholesterol-lowering drugs to treat familial hypercholesterolemia.

24 Sep 2020

Heart News and Research

Pitt team receives NIH award to optimize tissue-engineered vascular graft design

New drug offers hope for young boys with Duchenne muscular dystrophy

University of Minnesota receives funding to initiate research on diabetes drug as a COVID-19 treatment

FDA approves first drug for patients with hypereosinophilic syndrome in nearly 14 years

Novel technique helps detect heart damage in top-level competition dogs

Social inequities in Black and South Asian immigrants increase risk of severe COVID-19 infection

Study assesses cardiovascular and renal outcomes for ertugliflozin in patients with type 2 diabetes

Study highlights the importance of healthy placental development in pregnancy

Individuals with severe forms of COVID-19 disease can have compromised type I interferon responses

Scientists develop single-cell atlas of the normal human heart

Scientists create first atlas of human heart cells

Berlin researchers are pursuing the development of passive vaccination

New $1.5 million, multi-state data project to examine COVID-19 outcomes and treatments

NIA grant supports research on lifespan behavioral development and cognitive aging

Cellular and molecular map of the human heart could guide personalized medicine

Parental skin-to-skin contact dampens pain responses in newborn baby's brain

California expands privacy protection to public health workers amid threats

Stroke alarm clock may simplify and expedite time-sensitive acute stroke care

AI used to define the cytokine storm implicated in fatal COVID-19

Gruthan Bioscience to develop new class of cholesterol-lowering drugs

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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