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Machine learning can predict pediatric ECMO patients at risk of brain injury

When newborn babies or children with heart or lung distress are struggling to survive, doctors often turn to a form of life support that uses artificial lungs.

1 Oct 2020

Calibr's novel 'switchable' CAR-T cell therapy granted FDA's Fast Track designation

The U.S. Food and Drug Administration has granted Fast Track designation to a novel "switchable" CAR-T cell therapy developed by Calibr, a division of Scripps Research, in a move to accelerate the drug development and review process.

1 Oct 2020

Compounds repurposed from malaria treatment can kill diarrheal pathogen

A class of compounds used for malaria treatment also kill the intestinal parasite Cryptosporidium, a leading cause of diarrheal disease and death in children that has no cure, a multi-institution collaboration of researchers found in a new study.

1 Oct 2020

Study shows how cancer cells gain access to nerve signal to enter the bloodstream

Tumors come in many shapes and forms--curable or deadly, solid or liquid, lodged inside the brain, bone, or other tissues. One thing they all have in common, however, is a knack for molecular deceit.

1 Oct 2020

Immunotherapy drug improves survival over standard chemotherapy for lung cancer patients

The immunotherapy drug atezolizumab improves survival over standard chemotherapy for many patients with newly diagnosed non-small cell lung cancer (NSCLC), according to a new study led by Yale Cancer Center (YCC) researchers.

1 Oct 2020

Researchers identify a promising method to treat multiple sclerosis

Seema Tiwari-Woodruff, a professor of biomedical sciences in the School of Medicine at the University of California, Riverside, and her colleagues have received a grant of $373,000 from the National Multiple Sclerosis Society for a project in which her lab will select the five best candidate compounds to speed up nerve impulses, a promising new avenue to treat multiple sclerosis.

1 Oct 2020

NIH awards grants for using bioengineered models to improve clinical trial design

Clinical Trials on a Chip researchers plan to build and test common and rare disease models to help improve the clinical trial process.

30 Sep 2020

New trial to evaluate anti-TNF drug as a treatment for COVID-19 patients begins

Researchers at the University of Oxford are starting a new study to explore the effectiveness of the anti-tumour necrosis factor (anti-TNF) drug adalimumab as a treatment for patients with COVID-19 in the community, especially care homes.

30 Sep 2020

Sky-high drug prices driven by pharma profits, House Dems charge

Enormous drug company profits are the primary driver of soaring prescription drug prices in America, according to a damning investigation that Democrats on the House Oversight Committee began releasing Wednesday.

30 Sep 2020

Methamphetamine use linked to risky sexual behavior

Recreational use of the illicit drug methamphetamine has long been associated with increases in overall impatient and risky behavior.

30 Sep 2020

UM171 molecule saves life of young man suffering from severe aplastic anemia

In a world first, a young man suffering from severe aplastic anemia who could not be helped by standard treatments has been given a life-saving blood transplant with the made-in-Canada UM171 molecule.

30 Sep 2020

Cannabinoids can contribute to negative respiratory health events in older adults with COPD

Cannabinoids, a class of prescription pills that contain synthetically-made chemicals found in marijuana, are associated with a 64 per cent increase in death among older adults with chronic obstructive pulmonary disease (COPD), according to the first published data on the impact of cannabinoids on the respiratory health of individuals with the lung disease.

30 Sep 2020

Researchers create drug-like compounds to destroy coronavirus' frameshifting element

Scripps Research chemist Matthew Disney, PhD, and colleagues have created drug-like compounds that, in human cell studies, bind and destroy the pandemic coronavirus' so-called "frameshifting element" to stop the virus from replicating.

30 Sep 2020

Cancer chemotherapy changes the function of cells that repair heart injury

Cancer chemotherapy changes the function of cells that repair heart injury, researchers at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) discovered.

30 Sep 2020

A TLR2 agonist reduces SARS-CoV-2 in upper respiratory tract of ferret model

In a recent bioRxiv* preprint paper, Professor Miles W. Carroll et al. study an agonist for reducing the SARS-CoV-2's viral load. They show that prophylactic intra-nasal administration of TLR2/6 (toll-like receptor) agonist, INNA-051, reduces viral RNA in the nose and throat, in a ferret model.

30 Sep 2020

Researchers develop research model to understand the impact of coronavirus on lungs

Scientists at Boston University's National Emerging Infectious Diseases Laboratories (NEIDL) and the Center for Regenerative Medicine (CReM) joined forces to develop the most relevant research model possible for understanding how the coronavirus virus impacts the lungs, by engineering living, "breathing" human lung cells from stem cells for the task.

30 Sep 2020

Drugs News and Research

Machine learning can predict pediatric ECMO patients at risk of brain injury

Calibr's novel 'switchable' CAR-T cell therapy granted FDA's Fast Track designation

Compounds repurposed from malaria treatment can kill diarrheal pathogen

Study shows how cancer cells gain access to nerve signal to enter the bloodstream

Immunotherapy drug improves survival over standard chemotherapy for lung cancer patients

Researchers identify a promising method to treat multiple sclerosis

NIH awards grants for using bioengineered models to improve clinical trial design

New trial to evaluate anti-TNF drug as a treatment for COVID-19 patients begins

Sky-high drug prices driven by pharma profits, House Dems charge

Methamphetamine use linked to risky sexual behavior

UM171 molecule saves life of young man suffering from severe aplastic anemia

Cannabinoids can contribute to negative respiratory health events in older adults with COPD

Researchers create drug-like compounds to destroy coronavirus' frameshifting element

Cancer chemotherapy changes the function of cells that repair heart injury

A TLR2 agonist reduces SARS-CoV-2 in upper respiratory tract of ferret model

Researchers develop research model to understand the impact of coronavirus on lungs

Study shows how Cisplatin chemotherapy leads to neuronal apoptosis

Gut bacteria may play a role in prostate cancer therapies

Novel nasal treatment could protect people from COVID-19

Blocking the self-destruction process of enzymes can mitigate age-related diseases

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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