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MET amplification identified as a potentially actionable driver for non-small cell lung cancer

A study led by D. Ross Camidge, MD, PhD, director of thoracic oncology at the University of Colorado School of Medicine and CU Cancer Center member, has helped to define MET amplification as a rare but potentially actionable driver for non-small cell lung cancer (NSCLC).

20 Jul 2021

Research reveals clues to how a molecule improves appearance of surgery scars

Surgical scars treated with a molecule called alphaCT1 showed a long-term improvement in appearance when compared to control scars, according to multicenter, controlled Phase II clinical trials - a finding that could help surgeons improve patient outcomes.

20 Jul 2021

Targeting Piezo1 protein may be a new and ideal strategy to cure multiple sclerosis

In a new University of California, Irvine-led study, researchers found that a certain protein prevented regulatory T cells (Tregs) from effectively doing their job in controlling the damaging effects of inflammation in a model of multiple sclerosis (MS), a devastating autoimmune disease of the nervous system.

20 Jul 2021

Next-generation COVID-19 vaccine provides robust immunity against SARS-CoV-2 in mice

Researchers in Canada have developed an adenoviral vector-based vaccine against coronavirus disease 2019 (COVID-19) that induced robust immune protection against the ancestral strain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in mice.

20 Jul 2021

Child with Bachmann-Bupp Syndrome successfully treated in just 16 months

Diagnosing a rare medical condition is difficult. Identifying a treatment for it can take years of trial and error. In a serendipitous intersection of research expertise, an ill patient in this case a child and innovative technology, Bachmann-Bupp Syndrome has gone from a list of symptoms to a successful treatment in just 16 months.

20 Jul 2021

ATN framework can be extended to detect frontotemporal degeneration

Alzheimer's disease and related diseases can still only be confirmed in deceased patients' brains via autopsy.

20 Jul 2021

Study reports on COVID-19 vaccine uptake and antibody prevalence in England during May 2021

A new study reports this finding, along with varying antibody prevalence among different groups and regions and between different age groups. In the current paper, available as a preprint on the medRxiv* server, the results of the sixth round of the REACT-2 study are reported.

20 Jul 2021

Graduate student receives NIH grant to study specific molecule’s role in healthy neurodevelopment

Raymundo Hernandez was always drawn to psychology - that is, until he took his first neurobiology class as an undergraduate.

20 Jul 2021

Scientists identify key role of p38-MK2 pathway in determining cell fate in response to stress

Living organisms are often exposed to stress stimuli generated either by external or internal factors, and they need to respond accordingly.

20 Jul 2021

Yeast expressed, RBD-based vaccine provides robust immune responses against SARS-CoV-2

The ongoing coronavirus disease (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused over 190 million cases worldwide. Of these, over 4 million have died due to the infection.

20 Jul 2021

Protein consumption at breakfast can increase muscle size and function, finds study

Proteins constitute an essential dietary component that help in the growth and repair of the body. Composed of long chains of amino acids, proteins promote the growth of skeletal muscles, the group of muscles that help us move.

20 Jul 2021

Exhausted T cells linked to increased risk of COVID-19 mortality

New research led by Nadia R. Roan of Gladstone Institutes and the University of California, San Francisco, finds a correlation between high numbers of inflammatory CXCR4+ T cells and regulatory T cells specific to SARS-CoV-2 and dying from infection. In contrast, people who recovered from severe COVID-19 illness were more likely to have many SARS-CoV-2-specific T cells that perform homeostatic proliferation.

20 Jul 2021

UH researcher receives $2.7 million grant to detect cancer biomarkers in blood by counting exosomes

University of Houston engineering researcher Wei-Chuan Shih has been awarded $2.7 million from the National Institute of Biomedical Imaging and Bioengineering to detect cancer biomarkers in blood by counting exosomes.

20 Jul 2021

Past SARS-CoV-2 infection enhances mRNA vaccine-induced neutralization of variants of concern

Researchers in the United States have conducted a study suggesting that individuals previously infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibit better neutralizing activity against variants of concern following vaccination against coronavirus disease 2019 (COVID-19) than previously uninfected vaccinees.

19 Jul 2021

Neutralizing antibodies persist against SARS-CoV-2 at least a year after infection

Researchers in Finland have conducted a study showing that the neutralizing bodies generated following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – generally persist for at least a year.

19 Jul 2021

A path to treat currently untreatable cases of cystic fibrosis is clearly achievable, study suggests

An experimental drug reported in Nature Communications suggests that a "path is clearly achievable" to treat currently untreatable cases of cystic fibrosis disease caused by nonsense mutations.

19 Jul 2021

Study finds sex differences in astrocyte-mediated synaptic connectivity during brain development

During development, brain cells may find different ways to connect with each other based on sex, according to researchers at the Marshall University Joan C. Edwards School of Medicine.

19 Jul 2021

Chemical modification in RNA molecules may offer protection against liver disease

A chemical modification that occurs in some RNA molecules as they carry genetic instructions from DNA to cells' protein-making machinery may offer protection against non-alcoholic fatty liver, a condition that results from a build-up of fat in the liver and can lead to advanced liver disease, according to a new study by UCLA researchers.

19 Jul 2021

Deadly spider venom could help prevent damage from heart attacks

A potentially life-saving treatment for heart attack victims has been discovered from a very unlikely source - the venom of one of the world's deadliest spiders.

19 Jul 2021

Scientists deconstruct the protein-based machine responsible for SARS-CoV-2 replication

In February 2020, a trio of bio-imaging experts were sitting amiably around a dinner table at a scientific conference in Washington, D.C., when the conversation shifted to what was then a worrying viral epidemic in China.

19 Jul 2021

Protein C News and Research

MET amplification identified as a potentially actionable driver for non-small cell lung cancer

Research reveals clues to how a molecule improves appearance of surgery scars

Targeting Piezo1 protein may be a new and ideal strategy to cure multiple sclerosis

Next-generation COVID-19 vaccine provides robust immunity against SARS-CoV-2 in mice

Child with Bachmann-Bupp Syndrome successfully treated in just 16 months

ATN framework can be extended to detect frontotemporal degeneration

Study reports on COVID-19 vaccine uptake and antibody prevalence in England during May 2021

Graduate student receives NIH grant to study specific molecule’s role in healthy neurodevelopment

Scientists identify key role of p38-MK2 pathway in determining cell fate in response to stress

Yeast expressed, RBD-based vaccine provides robust immune responses against SARS-CoV-2

Protein consumption at breakfast can increase muscle size and function, finds study

Exhausted T cells linked to increased risk of COVID-19 mortality

UH researcher receives $2.7 million grant to detect cancer biomarkers in blood by counting exosomes

Past SARS-CoV-2 infection enhances mRNA vaccine-induced neutralization of variants of concern

Neutralizing antibodies persist against SARS-CoV-2 at least a year after infection

A path to treat currently untreatable cases of cystic fibrosis is clearly achievable, study suggests

Study finds sex differences in astrocyte-mediated synaptic connectivity during brain development

Chemical modification in RNA molecules may offer protection against liver disease

Deadly spider venom could help prevent damage from heart attacks

Scientists deconstruct the protein-based machine responsible for SARS-CoV-2 replication

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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