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Tumors use unique mechanism to switch on regulatory T cells for protection

Immunologists at St. Jude Children's Research Hospital have discovered that tumors use a unique mechanism to switch on regulatory T cells to protect themselves from attack by the immune system.

24 Feb 2021

New center established at NYU Langone Health to expand psychedelic research and training

Philanthropic support from several donors totaling over $10 million will allow NYU Langone Health to advance its already world-renowned reputation in the field of psychedelic medicine through the establishment of a one-of-a-kind center dedicated to expanding research and professional medical training in this resurging field.

24 Feb 2021

Study shows prevalence of inappropriate treatment for uncomplicated urinary tract infections

Nearly half of women with uncomplicated urinary tract infections received the wrong antibiotics and almost three-quarters received prescriptions for longer than necessary, with inappropriately long treatment durations more common in rural areas, according to a study of private insurance claims data published today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

24 Feb 2021

Magnesium-based micromotors used to improve rheumatoid arthritis symptoms

Rheumatoid arthritis is a chronic inflammatory disorder marked by joint pain, swelling and damage. Although medications, such as steroids, anti-inflammatory drugs and immunosuppressants, can help slow joint destruction and relieve pain, they have side effects and aren't completely successful.

24 Feb 2021

Study offers new insights into "Niemann-Pick type C disease"

In the journal Nature Communications, scientists of the German Center for Neurodegenerative Diseases (DZNE) report new findings on the mechanisms of "Niemann-Pick type C disease" (NPC).

24 Feb 2021

Endocrine-targeted therapies can prevent and treat endometrial cancer recurrence

In a new study led by Yale Cancer Center, researchers demonstrate sex hormones and insulin growth factors are associated with recurrence risk of endometrial cancer.

24 Feb 2021

New platform can help treat neurodegenerative diseases through regenerative medicine

Imagine if surgeons could transplant healthy neurons into patients living with neurodegenerative diseases or brain and spinal cord injuries.

24 Feb 2021

SARS-CoV-2 variants emerge during humoral immunity phase of acute COVID-19

A new preprint research paper posted to the bioRxiv server reports the rapid emergence of variants within an infected individual. The evolution of the virus within an infected host is not excluded by the close similarity between the consensus sequences of single-person SARS-CoV-2, since the number of viral copies is at its peak soon after infection occurs and before the host develops adaptive immunity.

23 Feb 2021

Slight differences can help distinguish between two similar pediatric brain conditions

Slight differences in clinical features can help physicians distinguish between two rare but similar forms of autoimmune brain inflammation in children, a new study by UT Southwestern scientists suggests.

23 Feb 2021

Phase 1 clinical trial shows promising results for monoclonal antibodies against MERS coronavirus

A randomized, placebo-controlled Phase 1 clinical trial of two monoclonal antibodies (mAbs) directed against the coronavirus that causes Middle East respiratory syndrome (MERS) found that they were well tolerated and generally safe when administered simultaneously to healthy adults.

23 Feb 2021

GSK-3 inhibitors show promise in treating coronavirus infections

Researchers in the United States have suggested a new approach to treating infection with coronaviruses such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

23 Feb 2021

'Phage therapy' helps treat mice infected with multidrug-resistant Klebsiella pneumoniae

Using viruses instead of antibiotics to tame troublesome drug-resistant bacteria is a promising strategy, known as bacteriophage or "phage therapy."

23 Feb 2021

mRNA Therapeutics – Analytical and Bioanalytical Characterization

NewsMed interviews Anette Bak from AstraZeneca about her research on developments in mRNA therapeutics that she will present at Pittcon 2021.

From Pittcon 23 Feb 2021

Researchers investigate how CF patients respond to COVID-19

So far, based on clinical data, patients with cystic fibrosis (CF) don't appear to be especially susceptible to COVID-19, and when they do get infected, they don't seem to get sicker. But Ruobing (Ruby) Wang, MD, a physician-scientist in the Division of Pulmonary Medicine at Boston Children's Hospital, cares for patients with CF and thinks there is more to the story.

23 Feb 2021

Review highlights symptoms, effects and probable causes of tinnitus

According to research conducted by JCDR, at least 9 out of 10 adults suffer from low health literacy in India. Health literacy is a vital aspect of any nation's growth - be it developed, underdeveloped, or a developing nation.

22 Feb 2021

Study explores the effects of COVID-19 on Black and Latino individuals living with HIV

With the COVID-19 pandemic taking a disproportionate toll on low-income people of color, a research team headed by Marya Gwadz of the Silver School of Social Work at New York University set out to understand the ways the pandemic may put individuals at risk for adverse outcomes, and the ways they successfully adapted to and coped with the emerging pandemic, focused on those from low-socioeconomic status backgrounds who have lived with HIV for a decade or longer.

22 Feb 2021

In vivo imaging reveals how anti-CD20 antibodies guide the immune system to attack tumors

Monoclonal antibodies are part of the therapeutic arsenal for eliminating cancer cells. Some make use of the immune system to act and belong to a class of treatment called "immunotherapies." But how do these antibodies function within the tumor? And how can we hope to improve their efficacy?

22 Feb 2021

Current monoclonal antibodies less potent against SARS-CoV-2 variants

Researchers at the New York University Grossman School of Medicine and Biohaven Pharmaceuticals found that the REGN10933 and REGN10987 combination was 9.1-fold less potent on the B.1.351 variant, which emerged in South Africa, and 16.2-fold less potent on mink cluster 5.

22 Feb 2021

HIV-positive people with severe immunosuppression, APOE4 gene may have increased risk for dementia

People living with the human immunodeficiency virus (HIV) who have a history of severe immunosuppression and at least one copy of the Alzheimer's disease-related gene variant APOE4, might see a compounded adverse effect on the circuitry that impacts memory.

22 Feb 2021

Scientists find new therapeutic approach to effectively treat age-related macular degeneration

Runt-related transcription factor 1 (RUNX1) has been linked to retinal neovascularization and the development of abnormal blood vessels, which result in vision loss in diabetic retinopathy.

22 Feb 2021

Therapy News and Research

Tumors use unique mechanism to switch on regulatory T cells for protection

New center established at NYU Langone Health to expand psychedelic research and training

Study shows prevalence of inappropriate treatment for uncomplicated urinary tract infections

Magnesium-based micromotors used to improve rheumatoid arthritis symptoms

Study offers new insights into "Niemann-Pick type C disease"

Endocrine-targeted therapies can prevent and treat endometrial cancer recurrence

New platform can help treat neurodegenerative diseases through regenerative medicine

SARS-CoV-2 variants emerge during humoral immunity phase of acute COVID-19

Slight differences can help distinguish between two similar pediatric brain conditions

Phase 1 clinical trial shows promising results for monoclonal antibodies against MERS coronavirus

GSK-3 inhibitors show promise in treating coronavirus infections

'Phage therapy' helps treat mice infected with multidrug-resistant Klebsiella pneumoniae

mRNA Therapeutics – Analytical and Bioanalytical Characterization

Researchers investigate how CF patients respond to COVID-19

Review highlights symptoms, effects and probable causes of tinnitus

Study explores the effects of COVID-19 on Black and Latino individuals living with HIV

In vivo imaging reveals how anti-CD20 antibodies guide the immune system to attack tumors

Current monoclonal antibodies less potent against SARS-CoV-2 variants

HIV-positive people with severe immunosuppression, APOE4 gene may have increased risk for dementia

Scientists find new therapeutic approach to effectively treat age-related macular degeneration

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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