Neuroscience News and Research

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Research provides new clues to understand link between deficits of AGPO-3, depression

The link between deficits of omega-3 poly-unsaturated fatty acids and the onset of depressive disorders is not new in the medical field. However, what has not been known until now is the brain mechanism by which diet can condition mental health to a certain extent.

5 Feb 2011

North Shore-LIJ begins patient enrollment in epilepsy research study

In the United States, epilepsy affects nearly one million women of childbearing potential and whether there is increased infertility in women with epilepsy is presently unknown. People with epilepsy have been reported to have fewer children, however, the specific factors contributing to this lower birth rate are unknown.

5 Feb 2011

Salk Institute receives $2.3 million CIRM grant for translational research on Parkinson's disease

The Salk Institute has been awarded a $2.3 million grant by the California Institute for Regenerative Medicine for translational research focusing on developing a novel stem cell based therapy for Parkinson's disease.

4 Feb 2011

Merck reports GAAP net income of $861 million for 2010

Merck, known as MSD outside the United States and Canada, today announced financial results for the fourth quarter and full year of 2010. The company reported non-GAAP (generally accepted accounting principles) earnings per share (EPS) for the fourth quarter of $0.88, which excludes purchase accounting adjustments, restructuring costs and merger-related expenses.

4 Feb 2011

Research unmasks long sought stem cell origin of carcinoma

A constellation of different stem cell populations within our skin help it to cope with normal wear and tear. By constantly proliferating, the stem cells allow skin to replenish itself, allowing each cell to be replaced by a new one about once a month. But the normal cycle of division and death within one or more of these stem cell types can sometimes be derailed by genetic mishaps. Such events are believed to spawn carcinomas and other deadly skin cancers, which are the mostly frequently diagnosed cancers in the United States.

4 Feb 2011

Maternal care makes baby's brain less vulnerable to stress

The quality and quantity of maternal milk and maternal-infant contact impact the stress response of the adult offspring, according to recent research published in Developmental Psychobiology.

4 Feb 2011

FDA sets new PDUFA date for AstraZeneca's ticagrelor

AstraZeneca announced today that the US Food and Drug Administration (FDA) has acknowledged receipt of the company's reply to the Complete Response Letter (CRL) for the ticagrelor New Drug Application (NDA).

4 Feb 2011

Scientists analyze relationship between drug abuse, recognition of basic emotions

University of Granada scientists have been the first to analyze the relation between drug abuse and recognition of basic emotions by drug-abusers.

4 Feb 2011

More careful regulation of FDA's Humanitarian Device Exemption in psychiatric patients needed

Warning that patients could be at risk, an interdisciplinary group of multinational investigators is calling on the U.S. Congress and federal regulators to tighten a law that permits use of brain devices to treat rare neuropsychiatric disorders without supporting clinical trials or stringent patient oversight.

4 Feb 2011

USF Health sponsors conference on Parkinson's disease and multiple sclerosis

Some of the country's leading physicians and researchers in the fields of Parkinson's disease and multiple sclerosis will gather later this month to discuss the latest advances in the diagnosis and treatment of these neurological disorders.

3 Feb 2011

Coordinated behavior occurs whether or not neurons are actually connected via synapses

The brain-awake and sleeping-is awash in electrical activity, and not just from the individual pings of single neurons communicating with each other. In fact, the brain is enveloped in countless overlapping electric fields, generated by the neural circuits of scores of communicating neurons.

3 Feb 2011

Concert and WRAIR enter CRADA to evaluate novel compound for seizure protection associated with TBI

Concert Pharmaceuticals, Inc. today announced that it has entered into a Cooperative Research and Development Agreement with the Walter Reed Army Institute of Research. The CRADA will allow the WRAIR to conduct preclinical testing on a novel compound derived from Concert's DCE Platform™ (deuterated chemical entity platform) for seizure protection associated with traumatic brain injury, a major public health concern.

3 Feb 2011

HealthCore, AstraZeneca collaborate to conduct real-world studies on disease states, treatment

AstraZeneca Pharmaceuticals LP and HealthCore, the health outcomes research subsidiary of WellPoint, today announced a collaborative agreement to conduct real-world studies designed to determine how to most effectively and economically treat disease.

3 Feb 2011

ImmunoCellular Therapeutics initiates enrollment in ICT-107 Phase II trial for GBM

ImmunoCellular Therapeutics, Ltd., a biotechnology company that is developing immune-based therapies for the treatment of various forms of cancer, announced today that the first patient has been enrolled in its Phase II trial of ICT-107 at the New Jersey Neuroscience Institute at JFK Medical Center. ICT-107 is the company's dendritic cell based cancer vaccine candidate for the treatment of glioblastoma multiforme (GBM).

3 Feb 2011

Ritalin may help improve brain function in children with iron deficiency

Ritalin may help improve brain function in adolescent rats that were iron deficient during infancy, according to a team of Penn State neuroscientists. This may have implications for iron-deficient human infants as well.

3 Feb 2011

International scientist team identifies gene mutation strongly linked to schizophrenia

In a major advance for schizophrenia research, an international team of scientists, led by Jonathan Sebat, PhD, assistant professor of psychiatry and cellular and molecular medicine at the University of California, San Diego School of Medicine, has identified a gene mutation strongly linked to the brain disorder - and a signaling pathway that may be treatable with existing compounds.

3 Feb 2011

Malarial drugs may help treat specific form of frontotemporal dementia

Frontotemporal dementia is caused by a breakdown of nerve cells in the frontal and temporal region of the brain, which leads to, among other symptoms, a change in personality and behavior. The cause of some forms of frontotemporal dementia is a genetically determined reduction of a hormone-like growth factor, progranulin.

3 Feb 2011

Older people with metabolic syndrome may face high risk of developing memory loss

Older people with larger waistlines, high blood pressure and other risk factors that make up metabolic syndrome may be at a higher risk for memory loss, according to a study published in the February 2, 2011, online issue of Neurology, the medical journal of the American Academy of Neurology.

3 Feb 2011

New study to address causes and risk factors of ovarian cancer in African American women

University Hospitals Case Medical Center and Case Western Reserve University School of Medicine are conducting an important new study addressing the lack of knowledge about causes and risk factors for ovarian cancer in African American women. The five-year study is funded by the National Cancer Institute through Case Western Reserve University School of Medicine.

2 Feb 2011

FDA issues Complete Response Letter for approval of Eisai's rabeprazole sodium extended-release capsules

Eisai announced today that the company received a Complete Response Letter from the United States Food and Drug Administration (FDA) regarding the New Drug Application (NDA) of rabeprazole sodium extended-release capsules, 50 mg, an investigational proton pump inhibitor (PPI) under review for the healing and long-term maintenance of healing and symptom resolution of erosive gastroesophageal reflux disease (GERD), and for the treatment of daytime and nighttime heartburn and other symptoms of non-erosive GERD.

2 Feb 2011

Neuroscience News and Research

Research provides new clues to understand link between deficits of AGPO-3, depression

North Shore-LIJ begins patient enrollment in epilepsy research study

Salk Institute receives $2.3 million CIRM grant for translational research on Parkinson's disease

Merck reports GAAP net income of $861 million for 2010

Research unmasks long sought stem cell origin of carcinoma

Maternal care makes baby's brain less vulnerable to stress

FDA sets new PDUFA date for AstraZeneca's ticagrelor

Scientists analyze relationship between drug abuse, recognition of basic emotions

More careful regulation of FDA's Humanitarian Device Exemption in psychiatric patients needed

USF Health sponsors conference on Parkinson's disease and multiple sclerosis

Coordinated behavior occurs whether or not neurons are actually connected via synapses

Concert and WRAIR enter CRADA to evaluate novel compound for seizure protection associated with TBI

HealthCore, AstraZeneca collaborate to conduct real-world studies on disease states, treatment

ImmunoCellular Therapeutics initiates enrollment in ICT-107 Phase II trial for GBM

Ritalin may help improve brain function in children with iron deficiency

International scientist team identifies gene mutation strongly linked to schizophrenia

Malarial drugs may help treat specific form of frontotemporal dementia

Older people with metabolic syndrome may face high risk of developing memory loss

New study to address causes and risk factors of ovarian cancer in African American women

FDA issues Complete Response Letter for approval of Eisai's rabeprazole sodium extended-release capsules

Event guide: 8th Neuroimmunology Drug Development Summit 2026 eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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