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Study reveals innovative gene therapy approach to regenerate functional new neurons

Spinal cord injury (SCI) often causes disability and seriously compromises quality of life. While decades of research have made significant progress in axonal regeneration after SCI, most of the interventions have not been translated into clinical therapies.

18 Dec 2020

COVID-19 pandemic highlights the risk of using systemic corticosteroids

Healthcare workers in tropical and sub-tropical settings where strongyloidiasis is prevalent or caring for patients who have travelled to such areas, need to maintain a high level of awareness about the use of corticosteroids, including when this class of anti-inflammatories is given to patients suspected of infection with SARS-CoV-2.

17 Dec 2020

Research examines processes of lung scarring and chronic rejection of organ after transplantation

Two new papers examine the processes of lung scarring and chronic rejection of the organ after transplantation, and potential therapies to stop the graft, or transplanted organ and its tissue, from failing.

17 Dec 2020

Regulating fas protein may be a route to prevent cancer relapse after immunotherapy

Mount Sinai researchers have solved one of the enduring mysteries of cancer immunotherapy: Why does it completely eliminate tumors in many patients, even when not all the cells in those tumors have the molecular target that the therapy is aimed at?

17 Dec 2020

New toolkit aims to maximize high-quality collection of thrombosis data in COVID-19 clinical studies

The ASH Research Collaborative and the International Society of Haemostasis and Thrombosis, two organizations with multidisciplinary expertise in blood clotting and bleeding disorders, have developed a toolkit to help clinical researchers from across medical disciplines design clinical trials that further the understanding of blood clotting events associated with COVID-19.

17 Dec 2020

MFCR awards new grants to support an emerging approach to cancer therapeutics

The Mark Foundation for Cancer Research has awarded five new grants in support of an important, emerging approach to cancer therapeutics.

17 Dec 2020

Study shows benefits of integrated palliative and oncology care for patients with advanced AML

A first-of-its-kind intervention integrating palliative care early in the course of cancer therapy for patients with advanced acute myeloid leukemia (AML), a highly aggressive cancer of the blood and bone marrow, resulted in substantial improvements in patients' quality of life, mood and end-of-life care, a team of investigators has found.

17 Dec 2020

No added risks to radiation therapy for cancer patients with COVID-19, says study

A team of radiation oncologists at the Zucker School of Medicine at Hofstra/Northwell in the United States aimed to determine if COVID-19 infected cancer patients receiving radiation therapy (RT) have any different outcome than non-infected patients.

17 Dec 2020

Low-intensity pulsed ultrasound combined with microbubbles might enhance chemotherapy delivery

Application of low-intensity pulsed ultrasound in combination with microbubbles might enhance the delivery of chemotherapy medication used for treating cancers.

17 Dec 2020

FAT1 mutations act as tumor suppressor and prevent cancer development, indicates study

Cancer metastasis, which is the dissemination of tumor cells into distant organs, is the leading cause of mortality in cancer patients. To undergo metastasis, cells must leave the primary tumor, circulate into the blood, colonize distant organs, and form distant metastasis.

17 Dec 2020

4E-BP proteins are key to unlock the antidepressant effect of ketamine in the brain

A group of proteins called 4E-BPs, involved in memory formation, is the key to unlocking the antidepressant effect of ketamine in the brain, according to researchers from three Canadian universities. The discovery could lead to better and safer treatments for certain patients suffering from major depression.

17 Dec 2020

Brain protein indicates a link between circadian rhythm dysfunction and Alzheimer's Disease

Fractured sleep, daytime sleepiness and other signs of disturbance in one's circadian rhythm are common complaints of people with Alzheimer's disease, and the problems only get worse as the disease progresses.

17 Dec 2020

Fluorescence guidance can enable surgeons to assess cancer tissues in real-time

A clinical research study published in the British Journal of Surgery shows that fluorescence guidance (where a fluorescent chemical compound re-emits light with a long wavelength) can enable a colorectal surgeon to assess cancer tissues visually and with more specificity in real-time during surgery, by utilising near-infrared (NIR) light from an administered fluorophore in conjunction with artificial intelligence (AI) methods.

17 Dec 2020

Study shows patients are more receptive to using mental health and wellness apps

Kaiser Permanente physicians and therapists now have the ability to refer their patients to evidenced-based mental health and wellness apps through the organization's electronic health record system.

17 Dec 2020

TRIUMF and Fusion Pharmaceuticals to develop next-generation radiopharmaceuticals

TRIUMF, Canada's particle accelerator center, today announced it has entered into a collaboration agreement with Fusion Pharmaceuticals Inc., a clinical-stage oncology company focused on developing next-generation radiopharmaceuticals as precision medicines.

17 Dec 2020

Researchers use new method to deliver anti-cancer drug to suppress tumor growth

Targeting drugs to cancer tissues is a major challenge in cancer treatment. Mesenchymal stem cells (MSCs) are known for their ability to find and target tumor cells in the body, but using MSCs for drug delivery has been tricky, because upon loading with drugs, MSCs lose their viability and migratory ability.

17 Dec 2020

Therapy News and Research

Study reveals innovative gene therapy approach to regenerate functional new neurons

COVID-19 pandemic highlights the risk of using systemic corticosteroids

Research examines processes of lung scarring and chronic rejection of organ after transplantation

Regulating fas protein may be a route to prevent cancer relapse after immunotherapy

New toolkit aims to maximize high-quality collection of thrombosis data in COVID-19 clinical studies

MFCR awards new grants to support an emerging approach to cancer therapeutics

Study shows benefits of integrated palliative and oncology care for patients with advanced AML

No added risks to radiation therapy for cancer patients with COVID-19, says study

Low-intensity pulsed ultrasound combined with microbubbles might enhance chemotherapy delivery

FAT1 mutations act as tumor suppressor and prevent cancer development, indicates study

4E-BP proteins are key to unlock the antidepressant effect of ketamine in the brain

Brain protein indicates a link between circadian rhythm dysfunction and Alzheimer's Disease

Fluorescence guidance can enable surgeons to assess cancer tissues in real-time

Study shows patients are more receptive to using mental health and wellness apps

TRIUMF and Fusion Pharmaceuticals to develop next-generation radiopharmaceuticals

Researchers use new method to deliver anti-cancer drug to suppress tumor growth

Oral hormone therapy significantly alters the metabolome of postmenopausal women

NET study: New theranostic approach effective in reducing tumor volume and extending lifespan

New guideline offers recommendations to use behavioral, psychological therapies for insomnia

New screening platform can be used to discover more effective drugs for type 1 diabetes

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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