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Research advances understanding of neuroimmune mechanisms in ASD

In the Biological Psychiatry special issue "Neuroimmune Mechanisms in Autism Spectrum Disorder", guest editor Professor Kimberley McAllister of the University of California, Davis, presents five reviews and three original research articles highlighting advances that are transforming the field of autism spectrum disorder (ASD) research.

23 Feb 2017

Study reveals mechanisms behind Zika transmission to fetus and adverse perinatal outcomes

Johns Hopkins researchers say that in early pregnancy in mice with complete immune systems, Zika virus can cross the placenta -- intended to protect the developing fetus -- and appears to lead to a high percentage of miscarriages and to babies born with thin brain tissue and inflammation in brain cells.

23 Feb 2017

Monash-Cardiff researchers gain new understanding of how HIV evades immune system

Monash University and Cardiff University researchers have come a step further in understanding how the human immunodeficiency virus (HIV) evades the immune system.

22 Feb 2017

Penn-led researchers gain better understanding of how T cells support long-lived plasma cells

If you've ever wondered how a vaccine given decades ago can still protect against infection, you have your plasma cells to thank. Plasma cells are long-lived B cells that reside in the bone marrow and churn out antibodies against previously encountered vaccines or pathogens.

22 Feb 2017

Estrogen therapy can lead to healthier teeth and gums in postmenopausal women, study suggests

Estrogen therapy has already been credited with helping women manage an array of menopause-related issues, including reducing hot flashes, improving heart health and bone density, and maintaining levels of sexual satisfaction.

22 Feb 2017

Scientists discover potent trigger of inflammatory disease

Institute scientists have revealed a potent inflammatory molecule released by dying cells triggers inflammation during necroptosis, a recently described form of cell death linked to inflammatory disease.

22 Feb 2017

First breath of newborn shapes lifelong immunological milieu of lungs

The lung is an important interface between the body and the outside environment: with each breath, a surface of roughly 100 square meters exchanges oxygen for carbon dioxide. More than 10,000 liters of air pass adult lungs every day and with this come numerous viruses, bacteria and pollutants, which need to be prevented from entering the body.

22 Feb 2017

Scientists explore role of salt and immune system in raising blood pressure of females

Many of us have noted how our hands and feet swell after eating too much salt. Now scientists are exploring how high salt intake can also make cells throughout the body of females swell, rupture, dump their contents and die, triggering an immune reaction that contributes to chronic high blood pressure.

22 Feb 2017

Study finds Mediterranean foods as key to reduce pain linked to obesity

Eating a Mediterranean diet could decrease the chances an overweight person will experience regular pain, new research suggests.

21 Feb 2017

Review focuses on benefits of mindfulness in aging populations

As mindfulness practices rise in popularity and evidence of their worth continues to accumulate, those who work with aging populations are looking to use the techniques to boost cognitive, emotional and physiological health.

21 Feb 2017

Research may show new ways to repress inflammation at outset

Researchers at the University of Tübingen, working with colleagues in other parts of Germany and in the United States, have identified an enzyme as a kind of biological gauge regulating inflammation in the human body.

21 Feb 2017

Listeria may pose severe risk of miscarriage in early stages of pregnancy

Listeria, a common food-borne bacterium, may pose a greater risk of miscarriage in the early stages of pregnancy than appreciated, according to researchers at the University of Wisconsin-Madison School of Veterinary Medicine studying how pathogens affect fetal development and change the outcome of pregnancy.

21 Feb 2017

MS treatment prevents symptoms of severe disease from worsening for five years, study shows

A type of treatment for multiple sclerosis that 'resets' the immune system may stop progression of the disease in nearly half of patients.

21 Feb 2017

Study opens way for targeted local treatments for patchy skin disorders

With the aid of thousands of skin biopsies and over a hundred kilograms of skin, researchers at Karolinska Institutet have observed how two subgroups of immune cell behave in healthy skin.

20 Feb 2017

Lower vitamin D levels increase risk of clinical relapse in Ulcerative Colitis patients, study finds

A new study led by researchers at Beth Israel Deaconess Medical Center has found that lower levels of vitamin D in the blood increase the risk of clinical relapse in patients with Ulcerative Colitis, an inflammatory bowel disease that causes long-lasting inflammation and ulcers in the colon.

17 Feb 2017

Research: Many ulcerative colitis patients taking conventional treatments describe disease as 'poorly controlled'

New research shows that nearly three-quarters of patients with moderate to severe ulcerative colitis (UC) taking conventional treatments describe their disease as ‘poorly controlled’ (continuous or regular experience of symptoms that negatively affect quality of life), with half saying they are somewhat or completely dissatisfied with their current medication; only 1% were completely satisfied with their current treatment.

17 Feb 2017

Researchers discover new pathway that may play key role in kidney transplant rejection

Researchers have identified a new pathway that likely plays an important role in rejection following kidney transplantation.

17 Feb 2017

Chronic exposure to common food additive alters nutrient absorption in small intestine

The ability of small intestine cells to absorb nutrients and act as a barrier to pathogens is "significantly decreased" after chronic exposure to nanoparticles of titanium dioxide, a common food additive found in everything from chewing gum to bread, according to research from Binghamton University, State University of New York.

17 Feb 2017

Doctors use targeted molecular drugs to treat fatal cancerous blood syndromes

Genomic testing of biopsies from patients with deadly, treatment-resistant cancerous blood syndromes called histiocytoses allowed doctors to identify genes fueling the ailments and use targeted molecular drugs to successfully treat them.

16 Feb 2017

HMS scientists listen to crosstalk between gut microbes and immune system

The human gut is home to some 100 trillion bacteria, comprising between 250 and 500 species. This astounding array of organisms, collectively known as the gut microbiome, is a powerful regulator of disease and health and has been implicated in conditions ranging from inflammatory bowel disease to multiple sclerosis.

16 Feb 2017

Inflammation News and Research

Research advances understanding of neuroimmune mechanisms in ASD

Study reveals mechanisms behind Zika transmission to fetus and adverse perinatal outcomes

Monash-Cardiff researchers gain new understanding of how HIV evades immune system

Penn-led researchers gain better understanding of how T cells support long-lived plasma cells

Estrogen therapy can lead to healthier teeth and gums in postmenopausal women, study suggests

Scientists discover potent trigger of inflammatory disease

First breath of newborn shapes lifelong immunological milieu of lungs

Scientists explore role of salt and immune system in raising blood pressure of females

Study finds Mediterranean foods as key to reduce pain linked to obesity

Review focuses on benefits of mindfulness in aging populations

Research may show new ways to repress inflammation at outset

Listeria may pose severe risk of miscarriage in early stages of pregnancy

MS treatment prevents symptoms of severe disease from worsening for five years, study shows

Study opens way for targeted local treatments for patchy skin disorders

Lower vitamin D levels increase risk of clinical relapse in Ulcerative Colitis patients, study finds

Research: Many ulcerative colitis patients taking conventional treatments describe disease as 'poorly controlled'

Researchers discover new pathway that may play key role in kidney transplant rejection

Chronic exposure to common food additive alters nutrient absorption in small intestine

Doctors use targeted molecular drugs to treat fatal cancerous blood syndromes

HMS scientists listen to crosstalk between gut microbes and immune system

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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