Apoptosis News and Research

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Apoptosis is programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells.

Researchers uncover small molecule that plays key role in protecting against cancer

In a new study, researchers have shown that a small molecule involved in the regulation of gene expression plays an important role in protecting against cancer.

31 Jan 2018

Scientists decipher molecular mechanism of the cell with relevance for cancer development

Achievement in the field of cancer research: Biologists and chemists at the University of Konstanz decipher a molecular mechanism of the cell with relevance for the development of cancer and the fight against that disease.

27 Jan 2018

Researchers uncover key protein that rescues progression of adult spinocerebellar ataxia

Spinocerebellar ataxia is a group of neurodegenerative diseases characterized by progressive incoordination of gait, and is often associated with poor coordination of hands, speech, and eye movements.

27 Jan 2018

TSRI scientists identify factors crucial to mesenchymal stem cell differentiation

Researchers at The Scripps Research Institute recently published a study in the journal Cell Death and Differentiation identifying factors crucial to mesenchymal stem cell differentiation, providing insight into how these cells should be studied for clinical purposes.

24 Jan 2018

Chinese researchers develop multifunctional vehicle to transport gene therapeutics

Gene editing is one of the hottest topics in cancer research. A Chinese research team has now developed a gold-nanoparticle-based multifunctional vehicle to transport the "gene scissors" to the tumor cell genome.

22 Jan 2018

Researchers identify new anti-inflammatory drug target

A new study suggests that parmodulins may provide anti-inflammatory and anti-thrombotic protection to endothelial cells, without interfering with clotting.

16 Jan 2018

The Virus That Causes Hand, Foot and Mouth Disease May Use Human Protein to Aid Infection

The human protein, prohibitin, may be used by the virus to enter motor neurons and cause the neurological complications of hand, foot and mouth disease.

12 Jan 2018

Human cardiac-muscle patches improve recovery from heart attack injury

Large, human cardiac-muscle patches created in the lab have been tested, for the first time, on large animals in a heart attack model. This clinically relevant approach showed that the patches significantly improved recovery from heart attack injury.

11 Jan 2018

New understanding of how molecules regulate enzyme could lead to potential cancer targets

New understandings of how molecules affect the activity of an enzyme could lead to potential targets for the treatment of cancers and neurodegenerative diseases.

5 Jan 2018

UC Davis expert expresses caution on genetically engineered HSCs

In a commentary published in the Jan. 4 issue of the New England Journal of Medicine, UC Davis researcher William Murphy expressed cautious optimism about efforts to genetically engineer hematopoietic stem cells (HSCs) to temporarily resist cell death during transplantation.

4 Jan 2018

Soil-dwelling bacterium produces potential weapon against melanoma

A type of soil-dwelling bacterium produces molecules that induce death in melanoma cells, research at Oregon State University shows.

4 Jan 2018

Selenium protects specialized neurons from cell death during postnatal development

Exactly 200 years ago, the Swedish scientist Jöns Jacob Berzelius discovered the trace element selenium, which he named after the goddess of the moon, Selene.

29 Dec 2017

Study findings could lead to less expensive and more effective cancer treatments

The latest generation of cancer treatments spring from the discovery that the human immune system is able to beat the disease. Like Dorothy in "The Wizard of Oz," what research teams around the world have spent decades searching for was right in their own backyard all along.

20 Dec 2017

Treatment for skin cancer could be more effective if combined with arthritis drug

Treatment for the most deadly form of skin cancer could be more effective if combined with a well-known drug for rheumatoid arthritis, new research has shown.

19 Dec 2017

Researchers use RNA nanotechnology to program exosomes for delivering effective cancer therapies

A new study shows that attaching antibody-like RNA nanoparticles to microvesicles can deliver effective RNA therapeutics such as small interfering RNA specifically to cancer cells.

13 Dec 2017

Scientists discover specific mechanism of Zika virus-associated microcephaly

Epidemiological studies show that in utero fetal infection with the Zika virus (ZIKV) may lead to microcephaly, an irreversible congenital malformation of the brain characterized by an incomplete development of the cerebral cortex.

11 Dec 2017

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

There's a continued drive towards making in vitro assays ever more translational towards in vivo models and ultimately the clinic. This ties in with the resurgence of phenotypic screening and is a response to the perceived poor translation of the traditional simple cell-based assays, often developed to study just single protein targets.

From Sartorius 5 Dec 2017

Process of removing cellular debris can fuel tumor growth in metastatic prostate cancer

The goal of any cancer treatment is to kill tumor cells. Yet, one little understood paradox of certain cancers is that the body's natural process for removing dead and dying cells can actually fuel tumor growth.

28 Nov 2017

Researchers explore new method of destroying tumor cells

Researchers from Lomonosov MSU Faculty of Biology have studied the stages of entosis, a process of cell death when one cell invades the other and gets digested inside of it. Entosis could become a new method of destroying cancer cells.

27 Nov 2017

Study: Alectinib 600 mg more effective than standard therapy in Asian ALK positive NSCLC patients

A subanalysis of the phase III ALEX study has shown that alectinib 600 mg twice daily is more effective than standard of care crizotinib in Asian patients with anaplastic lymphoma kinase (ALK) positive non-small-cell lung cancer (NSCLC), researchers report at the ESMO Asia 2017 Congress.

20 Nov 2017