Fracture News and Research

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Proper exsanguinator and tourniquet use poorly understood

Operating theater personnel have a poor understanding of appropriate exsanguinator and tourniquet use, show research results from a hospital in Ireland.

21 Jun 2012

$Study tests link between anesthesia type, complications and mortality after hip fracture surgery$

Study tests link between anesthesia type, complications and mortality after hip fracture surgery

Anesthesia type may affect complications and mortality after hip fracture surgery, according to a new study in the July issue of Anesthesiology. The Perelman School of Medicine at the University of Pennsylvania study tested the association between regional versus general anesthesia, and pulmonary and cardiovascular complications and mortality.

21 Jun 2012

Researchers discover distinct differences in how muscle affects two layers of bone in men, women

Researchers have long been aware that the progressive loss of muscle mass and bone density is a natural part of aging. But little work has investigated how muscle tissue affects the inner and outer layers of bone microstructure.

21 Jun 2012

Osteoporosis screening recommended for men at risk

Men at increased risk for osteoporosis should undergo bone mineral density testing with dual energy X-ray absorptiometry, concludes The Endocrine Society’s Clinical Practice Guideline “Osteoporosis in Men.”

20 Jun 2012

IOF review outlines pathophysiology, diagnosis and management of osteoporosis in young adults

Much of the research defining osteoporosis and fracture risk has focused on older adults, i.e. postmenopausal women and men over the age of 50. While older adults are at highest risk of osteoporosis and related fractures, the disease can also affect younger adults between 20 and 50 years of age. However, the diagnosis and management of osteoporosis in young adults is complicated by special challenges, including a complex pathophysiology and the related fact that there is no clear definition of osteoporosis, or of intervention thresholds, in this age group.

20 Jun 2012

Young men with HIV more likely to experience low bone mass

Young men being treated for HIV are more likely to experience low bone mass than are other men their age, according to results from a research network supported by the National Institutes of Health. The findings indicate that physicians who care for these patients should monitor them regularly for signs of bone thinning, which could foretell a risk for fractures. The young men in the study did not have HIV at birth and had been diagnosed with HIV an average of two years earlier.

20 Jun 2012

$Vertebral fractures flag vascular disease risk$

Vertebral fractures flag vascular disease risk

Abdominal aortic calcification in elderly men appears to be associated with vertebral fractures, say Moroccan scientists.

19 Jun 2012

C-section rates in US stabilize after eight years of steady increase

A new report on trends in women's health in the United States reveals the national C-section rate has held steady at 33 percent since 2009, leveling off after eight years of steady increase that was in part driven by scheduled, elective surgeries and a trend for increasing the repeat C-section.

19 Jun 2012

Clinical practice guidelines for management of osteoporosis in men

Osteoporosis in men causes significant morbidity and mortality. Today, the Endocrine Society released clinical practice guidelines (CPG) for management of this condition in men.

19 Jun 2012

$Combination of low-dose vitamin D and calcium does not reduce fracture risk in women$

Combination of low-dose vitamin D and calcium does not reduce fracture risk in women

Vitamin D and calcium are dietary requirements, but it's unclear how much is best for us. New draft findings by the United States Preventive Services Task Force conclude that for healthy, postmenopausal women, daily supplementation with low levels of vitamin D — up to 400 international units — combined with 1,000 milligrams of calcium, does not reduce fracture risk.

16 Jun 2012

$Hip fracture mortality increases with even mild cognitive decline$

Hip fracture mortality increases with even mild cognitive decline

Patients with just mild-to-moderate cognitive impairment have a high risk for nursing home admission and mortality during the first year after hip fracture, researchers report.

15 Jun 2012

Calcium with vitamin D supplements reduces risk of mortality in seniors

A study recently published in the Endocrine Society's Journal of Clinical Endocrinology and Metabolism (JCEM) suggests that vitamin D-when taken with calcium-can reduce the rate of mortality in seniors, therefore providing a possible means of increasing life expectancy.

15 Jun 2012

Osteoporosis self-reports unreliable measure for case defintions

Self-reports of incident osteoporosis in middle-aged and older women should not be relied on for a case definition, suggest study findings showing poor-to-moderate validity for this measure.

14 Jun 2012

$Environmental factors more important than genetic for vertebral fracture$

Environmental factors more important than genetic for vertebral fracture

Individual-specific environmental factors such as lifestyle have a greater influence on vertebral fracture risk than genetic factors, suggest study findings.

13 Jun 2012

$Extreme elderly account for two-thirds of osteoporotic hip fractures$

Extreme elderly account for two-thirds of osteoporotic hip fractures

Study findings presented at the Annual Congress of the European League Against Rheumatism, held in Berlin, Germany, show that nearly two-thirds of American osteoporotic hip fractures occur among individuals aged 80 years or older.

11 Jun 2012

What are vitamins?

Most people have heard of vitamin C and its effects upon the body; but how much do you know about other vitamins? How many even are there? And what do they all do?

8 Jun 2012

Study calls for more aggressive management of osteoporosis in the extreme elderly

A new American study presented today at EULAR 2012, the Annual Congress of the European League Against Rheumatism, calls for more aggressive management of osteoporosis in the extreme elderly as the true impact of osteoporotic hip fractures in those aged 80 years or older is unveiled.

8 Jun 2012

Branches following complex aortic aneurysm repair appear to be durable: Study

Branches following complex aortic aneurysm repair appear to be durable and are rarely the cause of patient death following complex aortic aneurysm repair according to a study presented at the 66th Vascular Annual Meeting presented by the Society for Vascular Surgery.

8 Jun 2012

Positive results from BioSpecifics’ XIAFLEX Phase III clinical program on Peyronie's disease

BioSpecifics Technologies Corp., a biopharmaceutical company developing first in class collagenase-based products marketed as XIAFLEX in the U.S. and XIAPEX in Europe and Eurasia, today announced positive top-line results from the IMPRESS (The Investigation for Maximal Peyronie's Reduction Efficacy and Safety Studies) Phase III clinical program of XIAFLEX for the treatment of Peyronie's disease, which was conducted by BioSpecifics' partner Auxilium Pharmaceuticals, Inc.

5 Jun 2012

$Gene variant linked to postmenopausal fracture risk$

Gene variant linked to postmenopausal fracture risk

Women who carry a variation in a gene involved in blocking bone morphogenic proteins are more likely to have fragility fractures than women without the variant, Greek research shows.

1 Jun 2012