Malignant News and Research

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New technique offers high-resolution 3D view inside tumors

Malignant tumors consume nutrients and oxygen faster than healthy cells. To do so, they recruit blood vessels in their environment. Depending on tumor type and genetic profile, there are differences on how tumors look internally.

26 May 2020

Cell-culture based in vitro test systems for antitumor drug screening

As we know, a malignant tumor is a complex system of mutated cells which constantly interacts with and involves healthy cells in the body.

21 May 2020

Scientists use new model to develop cancer stem cells

Liver cancer is one of the deadliest cancers. It is insidious and does not present symptoms until it has progressed considerably, at which point, treatment options are limited and chances of survival are low. The most common type of liver cancer is hepatocellular carcinoma (HCC).

21 May 2020

Durvalumab plus chemotherapy improved overall survival rate for mesothelioma patients

PrECOG, LLC is reporting clinical efficacy and biomarker analyses from its single-arm phase two study PrE0505 for the initial treatment of patients with malignant pleural mesothelioma.

20 May 2020

Sleep apnea may increase the risk of severe COVID-19, say researchers

An analysis conducted by researchers at the University of Turku and Turku University Hospital in Finland has suggested that obstructive sleep apnea (OSA) may be a risk factor for severe coronavirus disease 2019 (COVID-2019).

19 May 2020

Study shows how normal RAS interacts with mutated RAS in living cells

Many cancer medications fail to effectively target the most commonly mutated cancer genes in humans, called RAS.

19 May 2020

Study shows how cancer protein changes may accelerate tumorigenesis and metastasis

Understanding the genetic mutations and protein changes that take place in the progression of cancer is key to its treatment. Mutations in the gene TP53 and concomitant mutant p53 proteins in cancer cells have become notorious over the course of multiple studies of several different types of cancers.

18 May 2020

First detailed study of the epigenetic landscape of human tumor organoids

The researcher Manel Esteller performs the first massive epigenetic characterization in organoids or 3D cancer cultures and makes the data available to the research community to facilitate new findings on tumor development and progression.

15 May 2020

Researchers find higher prevalence of benign gynecologic lesions than previously reported

Over the last decade researchers have become concerned about a possible link between a benign gynecologic lesion called endosalpingiosis (ES) and ovarian cancer.

13 May 2020

First detailed study of the epigenetic landscape of human tumor organoids

Frequently, promising cancer therapies fail when applied to patients in the real clinical setting. This occurs despite many of these new treatments demonstrating promising results at the preclinical stage in the lab.

13 May 2020

Study provides further insights into the relationship between smoking and COVID-19

A Canadian study available on the preprint server medRxiv* shows that current smokers are slightly more likely than never smokers to test positive for coronavirus disease (COVID-19), but cautions about the possibility of reverse causality where smokers actually quit to avoid the disease.

12 May 2020

Novel radiotracer is an effective option for staging of prostate cancer

The novel radiopharmaceutical 18F-PSMA-1007 is both effective and readily available for detecting malignant prostate cancer lesions, according to research published in the April issue of The Journal of Nuclear Medicine.

11 May 2020

Common allergy medicine may improve survival in patients with malignant melanoma

Can a very common allergy medicine improve survival among patients suffering from the serious skin cancer, malignant melanoma? A new study from Lund University in Sweden indicates that this may be the case.

11 May 2020

Breakthrough study could revolutionize cancer treatment

Scientists have used 3D models to break down the DNA behavior of cancer cells, in a breakthrough new study which could revolutionize treatment for the disease.

10 May 2020

Excluding children from COVID-19 clinical trials may limit their treatment options

A new viewpoint article from Harvard Medical School, published in the journal JAMA Pediatrics, discusses the hesitancy to include children in coronavirus disease 2019 (COVID-19) clinical trials, potentially diminishing their therapeutic options in the long run.

7 May 2020

Growth hormone plays a key role in increasing survival rates following liver surgery

Growth hormone has been identified as playing a key role in reducing inflammation and increasing survival rates following liver surgery.

5 May 2020

Scientists decode herpes simplex virus 1

Until now, scientists had assumed that there are about 80 so-called open reading frames (ORFs) in the genome of herpes simplex virus 1 (HSV-1).

27 Apr 2020

Bayreuth researchers discover natural protective mechanism against cancer

Susanne Hellmuth and Olaf Stemmann from the Chair of Genetics at the University of Bayreuth have discovered a natural protective mechanism that leads to the programmed death of potentially diseased cells.

23 Apr 2020

A new method to deliver therapeutic proteins inside the body

A new way to deliver therapeutic proteins inside the body uses an acoustically sensitive carrier to encapsulate the proteins and ultrasound to image and guide the package to the exact location required, according to Penn State researchers. Ultrasound then breaks the capsule, allowing the protein to enter the cell.

23 Apr 2020

New study may offer a breakthrough in treating telomere diseases

Capping decades of research, a new study may offer a breakthrough in treating dyskeratosis congenita and other so-called telomere diseases, in which cells age prematurely.

21 Apr 2020

Malignant News and Research

New technique offers high-resolution 3D view inside tumors

Cell-culture based in vitro test systems for antitumor drug screening

Scientists use new model to develop cancer stem cells

Durvalumab plus chemotherapy improved overall survival rate for mesothelioma patients

Sleep apnea may increase the risk of severe COVID-19, say researchers

Study shows how normal RAS interacts with mutated RAS in living cells

Study shows how cancer protein changes may accelerate tumorigenesis and metastasis

First detailed study of the epigenetic landscape of human tumor organoids

Researchers find higher prevalence of benign gynecologic lesions than previously reported

First detailed study of the epigenetic landscape of human tumor organoids

Study provides further insights into the relationship between smoking and COVID-19

Novel radiotracer is an effective option for staging of prostate cancer

Common allergy medicine may improve survival in patients with malignant melanoma

Breakthrough study could revolutionize cancer treatment

Excluding children from COVID-19 clinical trials may limit their treatment options

Growth hormone plays a key role in increasing survival rates following liver surgery

Scientists decode herpes simplex virus 1

Bayreuth researchers discover natural protective mechanism against cancer

A new method to deliver therapeutic proteins inside the body

New study may offer a breakthrough in treating telomere diseases

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

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The impact of vibration on microscopy

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