Microscopy News and Research

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Researchers develop transgenic mice with the FRET biosensor for in vivo observation of necroptosis

Necroptosis is a form of regulated cell death (RCD) similar to apoptosis, the most commonly studied type of RCD. In contrast to apoptosis, plasma membrane rupture in necroptotic cells occurs at early time points.

9 Dec 2022

Landmark study challenges a 70-year-old theory of protein folding

A landmark study by researchers at the Department of Energy’s SLAC National Accelerator Laboratory and Stanford University reveals how a tiny cellular machine called TRiC directs the folding of tubulin, a human protein that is the building block of microtubules that serve as the cell’s scaffolding and transport system.

9 Dec 2022

Study reveals the presence of metal particles in cannabis vape liquids

Vaping can lead to exposure to metals, with lead levels exceeding tolerance limits in most of the analyzed samples.

9 Dec 2022

Study looks at the possibility of promoting hair cell regeneration using cell reprograming

About 430 million people around the world experience disabling hearing loss. In the United States, approximately 37.5 million adults report some trouble hearing. Hearing loss can happen when any part of the ear or the nerves that carry information on sounds to the brain do not work in the usual way.

8 Dec 2022

Research explores cell receptors for bat viruses to understand emergence of zoonotic diseases

New research shows that the closest bat virus relatives of the human Middle-East Respiratory Syndrome (MERS) coronavirus efficiently bind to bat ACE2 receptors as an entry point into these cells.

8 Dec 2022

Discovery of ’raspberry-shaped’ nanoparticle offers a way to enhance the effectiveness of existing drugs

A newly discovered technique, reported in the journal Nanoscale, offers a low-cost way to enhance the effectiveness of existing drugs.

7 Dec 2022

Leica Microsystems and ASI announce partnership to commercialize customizable microscope for advanced users

Single-objective light sheet microscope launched at Cell Bio 2022

From Leica Microsystems GmbH 7 Dec 2022

Study explores histopathological, serological, and clinical characteristics of PASC in patients with mild COVID-19

Researchers investigated the clinical, histopathological, imaging, and serological characteristics of post-acute sequelae of coronavirus disease 2019 (COVID-19) (PASC) in patients with mild COVID-19.

5 Dec 2022

Study shows how ketamine administration starkly changes neuronal activity patterns in the brain

Ketamine, an established anesthetic and increasingly popular antidepressant, dramatically reorganizes activity in the brain, as if a switch had been flipped on its active circuits, according to a new study by Penn Medicine researchers.

1 Dec 2022

Integrated approach addresses some of the biggest challenges in natural products drug discovery

Many successful drugs have their origins in natural sources such as plants, fungi, and bacteria, but screening natural products to identify potential drugs remains a difficult undertaking.

1 Dec 2022

Study provides a framework to guide the development of variant-resistant SARS-CoV-2 vaccines

Latest research findings show that vaccine-elicited neutralizing antibodies against SARS-CoV-2 are mostly directed against one of the two main domains of the viral entry machinery.

30 Nov 2022

Study reveals key details of how DREADD technology highjacks neuronal activity

Understanding of how neuronal activity modulates brain function is a key first step towards creating more effective drugs to treat a variety of neuropsychiatric illnesses, including depression, anxiety, schizophrenia, substance abuse, epilepsy, and others.

30 Nov 2022

The effect of evolutionary changes in prolonged SARS-CoV-2 infection in an immunosuppressed individual due to advanced HIV

Researchers assessed the impact of SARS-CoV-2 infection on cell death and fusion in an immunocompromised host.

30 Nov 2022

The effects of mechanical forces on musculoskeletal cells and tissues

In this interview, Dr. Marina Danalache, Lab leader at the Laboratory of Cell Biology, Department of Orthopedic Surgery, University of Tübingen talks to News-Medical Life Sciences about the ongoing research on the effects of mechanical forces on musculoskeletal cells and tissues, as well as how these forces mediate homeostasis and drive pathophysiological processes.

From Bruker BioAFM 30 Nov 2022

Microscopy News and Research

Researchers develop transgenic mice with the FRET biosensor for in vivo observation of necroptosis

Landmark study challenges a 70-year-old theory of protein folding

Study reveals the presence of metal particles in cannabis vape liquids

Study looks at the possibility of promoting hair cell regeneration using cell reprograming

Research explores cell receptors for bat viruses to understand emergence of zoonotic diseases

Discovery of ’raspberry-shaped’ nanoparticle offers a way to enhance the effectiveness of existing drugs

Leica Microsystems and ASI announce partnership to commercialize customizable microscope for advanced users

Study explores histopathological, serological, and clinical characteristics of PASC in patients with mild COVID-19

Study shows how ketamine administration starkly changes neuronal activity patterns in the brain

Integrated approach addresses some of the biggest challenges in natural products drug discovery

Study provides a framework to guide the development of variant-resistant SARS-CoV-2 vaccines

Study reveals key details of how DREADD technology highjacks neuronal activity

The effect of evolutionary changes in prolonged SARS-CoV-2 infection in an immunosuppressed individual due to advanced HIV

The effects of mechanical forces on musculoskeletal cells and tissues

Isolated monoclonal antibodies targeting SARS-CoV-2 S1/S2 cleavage effective against Delta and Omicron

Study on the immunogenicity of monkeypox virus messenger ribonucleic acid-based vaccine candidates

Molecular and cellular similarities identified in the brains of SARS-CoV-2 and Alzheimer's disease patients

Nanoparticles displaying SARS-CoV-1 and SARS-CoV-2 spikes induce broad antibody responses in animal model

How Can CPNs Revolutionize Medical Diagnostics?

Novel cancer-fighting nanoparticles co-deliver a chemotherapy drug and immunotherapy

Industry Focus eBook - Life Science Microscopy (2nd Edition) eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo