Paralysis News and Research

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Paralysis is the loss of muscle function in part of your body. It happens when something goes wrong with the way messages pass between your brain and muscles. Paralysis can be complete or partial. It can occur on one or both sides of your body. It can also occur in just one area, or it can be widespread. Paralysis of the lower half of your body, including both legs, is called paraplegia. Paralysis of the arms and legs is quadriplegia.

Polio eradication: an interview with Dr. Kathleen O’Reilly

Polio is a disease caused by a virus and results in paralysis, usually in the legs, of those affected. The paralysis is irreversible. In some extreme cases the virus spreads to the nerve cells of the brain reducing breathing capacity and this rarer form can be fatal.

16 Jul 2012

UMMS scientists identify new genetic mutation that causes familial ALS

A new genetic mutation that causes familial amyotrophic lateral sclerosis (ALS), a fatal neurological disorder also known as Lou Gehrig's Disease, has been identified by a team of scientists led by researchers at the University of Massachusetts Medical School (UMMS).

16 Jul 2012

Researchers link newly discovered gene mutations to ALS

Researchers have linked newly discovered gene mutations to some cases of the progressive fatal neurological disease amyotrophic lateral sclerosis - ALS, also known as Lou Gehrig's disease. Shedding light on how ALS destroys the cells and leads to paralysis, the researchers found that mutations in this gene affect the structure and growth of nerve cells.

16 Jul 2012

Powerful brain chemical systems work together to paralyze skeletal muscles during REM sleep

Two powerful brain chemical systems work together to paralyze skeletal muscles during rapid eye movement (REM) sleep, according to new research in the July 11 issue of The Journal of Neuroscience. The finding may help scientists better understand and treat sleep disorders, including narcolepsy, tooth grinding, and REM sleep behavior disorder.

12 Jul 2012

Poor vaccine uptake blamed for polio rise in Pakistan, Afghanistan

The number of cases of poliomyelitis per year in Pakistan and Afghanistan has more than doubled since 2006 despite improvements in available vaccine efficacy, show study findings in The Lancet.

10 Jul 2012

Polio elimination hindered by unvaccinated children in Pakistan and Afghanistan

Too few children have received sufficient doses of vaccine to wipe out polio in Pakistan and Afghanistan, two of only three countries in the world where endemic polio has yet to be eliminated, according to new research published Online First in The Lancet. The findings suggest that the newly introduced bivalent oral poliovirus vaccine (OPV) has the potential to eliminate polio in these countries if sufficient numbers of children could be reached by vaccination programmes.

4 Jul 2012

Researcher discovers how West Nile virus breaks through the tough blood-brain barrier to CNS

Mosquitoes are buzzing once again, and with that comes the threat of West Nile virus. Tom Hobman, a researcher with the Li Ka Shing Institute of Virology in the Faculty of Medicine & Dentistry, is making every effort to put an end to this potentially serious infection.

4 Jul 2012

New video article describes novel procedure that can monitor brain function

A new video article in JoVE, the Journal of Visualized Experiments, describes a novel procedure to monitor brain function and aid in functional mapping of patients with diseases such as epilepsy. This procedure illustrates the use of pre-placed electrodes for cortical mapping in the brains of patients who are undergoing surgery to minimize the frequency of seizures. This technique, while invasive, provides real-time analysis of brain function at a much higher resolution than current technologies.

27 Jun 2012

Clinical trial to examine functional benefits of combined therapy against stroke

Researchers at Vanderbilt University Medical Center are leading an international clinical trial to examine the functional benefits of a combined therapy to treat acute ischemic stroke, a type of stroke where a blood clot becomes lodged in an artery within the brain, reducing blood flow and depriving brain cells of oxygen. Eighty-seven percent of strokes are ischemic.

26 Jun 2012

PeriGen’s patient safety campaign raises awareness about shoulder dystocia

PeriGen, Inc., the leading innovator of fetal surveillance systems, is launching a patient safety campaign designed to inform pregnant women about shoulder dystocia, a serious childbirth complication.

26 Jun 2012

Gracilis muscle flap an effective treatment for facial paralysis in patients with NF2

A surgical technique using a muscle flap from the thigh restores facial motion—and the ability to smile—in patients with facial nerve paralysis resulting from neurofibromatosis type 2 (NF2), reports a study in this month's special "Operative Neurosurgery" supplement to Neurosurgery, official journal of the Congress of Neurological Surgeons.

21 Jun 2012

New understanding of how motor neurons die in spinal muscular atrophy patients

Cedars-Sinai's Regenerative Medicine Institute has pioneered research on how motor-neuron cell-death occurs in patients with spinal muscular atrophy, offering an important clue in identifying potential medicines to treat this leading genetic cause of death in infants and toddlers.

21 Jun 2012

Foods fortified with folic acid can prevent neural tube defects

Wheat flour milled in Nigeria will soon be fortified with folic acid, a B vitamin known for preventing serious or fatal birth defects of the spine and brain. Women who may become pregnant are encouraged to daily choose foods fortified with this essential vitamin because it can prevent the majority of these devastating birth defects known as neural tube defects.

21 Jun 2012

Positive interim data from Innate MIS416 Phase 1/2 clinical trial for chronic progressive MS

Innate Immunotherapeutics today announced positive interim data from the company's Phase 1/2 clinical trial of MIS416 in patients with chronic progressive multiple sclerosis (MS).

18 Jun 2012

Novel strategy for neutralizing unwanted molecules and clearing them from the body

Researchers have unveiled a novel strategy for neutralizing unwanted molecules and clearing them from the body.

18 Jun 2012

Novel technique can restore hand function in patients with spinal cord injury

Justin M. Brown, MD, reconstructive neurosurgeon at UC San Diego Health System, is one of only a few specialists in the world who have pioneered a novel technique to restore hand function in patients with spinal cord injury. In a delicate four-hour procedure, Brown splices together tiny nerve endings, only one millimeter in width, to help restore hand mobility. Most patients return home 24 hours after surgery.

16 Jun 2012

Anti-TNFs increase risk for herpes zoster infections in IRD patients

Patients with inflammatory rheumatic diseases who are treated with anti-tumor necrosis factor medications are significantly more likely to experience herpes zoster infections than those treated with traditional disease-modifying anti-rheumatic drugs, study results show.

15 Jun 2012

Anti-TNFs increase risk of shingles in patients with inflammatory rheumatic diseases

Patients with inflammatory rheumatic diseases (IRD) treated with anti-tumour necrosis factor medications (anti-TNFs) have a 75% greater risk of developing herpes zoster, or shingles, than patients treated with traditional disease modifying anti-rheumatic drugs (DMARDs), according to a meta-analysis presented today at EULAR 2012, the Annual Congress of the European League Against Rheumatism.

8 Jun 2012

New, more accurate test for paralytic shellfish poisons

For decades, U.S. fisheries have tested the algal toxin levels of shellfish caught for human consumption by processing a sample of the shellfish in a blender and injecting the resulting slurry into the abdomen of live mice, causing them to suffer seizures, paralysis, and death by suffocation.

25 May 2012

UofL receives Helmsley Charitable Trust grant to develop technology for paralyzed people

The University of Louisville has received $6.3 million from the Leona M. and Harry B. Helmsley Charitable Trust to support research in the Department of Neurological Surgery and the Kentucky Spinal Cord Injury Research Center at UofL developing the next generation of technology to help paralyzed people regain movement in their limbs and enhance their quality of life.

25 May 2012

Paralysis News and Research

Further Reading

Polio eradication: an interview with Dr. Kathleen O’Reilly

UMMS scientists identify new genetic mutation that causes familial ALS

Researchers link newly discovered gene mutations to ALS

Powerful brain chemical systems work together to paralyze skeletal muscles during REM sleep

Poor vaccine uptake blamed for polio rise in Pakistan, Afghanistan

Polio elimination hindered by unvaccinated children in Pakistan and Afghanistan

Researcher discovers how West Nile virus breaks through the tough blood-brain barrier to CNS

New video article describes novel procedure that can monitor brain function

Clinical trial to examine functional benefits of combined therapy against stroke

PeriGen’s patient safety campaign raises awareness about shoulder dystocia

Gracilis muscle flap an effective treatment for facial paralysis in patients with NF2

New understanding of how motor neurons die in spinal muscular atrophy patients

Foods fortified with folic acid can prevent neural tube defects

Positive interim data from Innate MIS416 Phase 1/2 clinical trial for chronic progressive MS

Novel strategy for neutralizing unwanted molecules and clearing them from the body

Novel technique can restore hand function in patients with spinal cord injury

Anti-TNFs increase risk for herpes zoster infections in IRD patients

Anti-TNFs increase risk of shingles in patients with inflammatory rheumatic diseases

New, more accurate test for paralytic shellfish poisons

UofL receives Helmsley Charitable Trust grant to develop technology for paralyzed people

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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