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CWRU grants technology transfer option to Disease Diagnostic Group to evaluate RAM device

Case Western Reserve University has granted a two-year technology transfer option to a research spinoff company developing a hand-held device that diagnoses malaria more quickly, simply and affordably than existing methods.

31 Jul 2013

CHOP researchers advance stem cell studies in childhood leukemia, Diamond Blackfan anemia

First produced only in the past decade, human induced pluripotent stem cells are capable of developing into many or even all human cell types. In new research, scientists reprogrammed skin cells from patients with rare blood disorders into iPSCs, highlighting the great promise of these cells in advancing understanding of those challenging diseases-and eventually in treating them.

31 Jul 2013

AstraZeneca, FibroGen partner to develop, commercialize anemia drug candidate FG-4592

AstraZeneca and FibroGen today announced that they have entered into a strategic collaboration to develop and commercialize FG-4592, a first-in-class oral compound in late stage development for the treatment of anemia associated with chronic kidney disease and end-stage renal disease.

31 Jul 2013

Interferon-free treatment for genotype-1b hepatitis C patients: an interview with Professor Wulf Boecher, Boehringer Ingelheim

Genotype 1 is, worldwide, the most prevalent genotype of the hepatitis C virus. It accounts for around seventy percent of all hepatitis C infections.

30 Jul 2013

Rapamycin extends mice lifespan but has limited effects on aging

The body's repair mechanisms begin to fail with increasing age. As a result, signs of wear and tear appear and the risk for many diseases, including Alzheimer's disease, diabetes, cardiovascular disorders and cancer, increases.

26 Jul 2013

Fixed-ratio transfusion protocol in trauma patients is feasible, but wastes blood plasma

The use of a 1:1:1 blood transfusion protocol in patients with severe trauma is feasible in hospitals, although it is associated with higher waste of plasma, according to a randomized trial published in CMAJ (Canadian Medical Association Journal).

16 Jul 2013

Nerves play critical role in development and spread of prostate tumors, say researchers

Researchers at Albert Einstein College of Medicine of Yeshiva University have found that nerves play a critical role in both the development and spread of prostate tumors. Their findings, using both a mouse model and human prostate tissue, may lead to new ways to predict the aggressiveness of prostate cancer and to novel therapies for preventing and treating the disease. The study published online today in the July 12 edition of Science.

12 Jul 2013

Researchers discover new class of antimalarial compounds

Despite renewed global efforts for eradication, malaria continues to exert devastating effects on human health. An estimated 220 million people are infected each year by malaria-causing Plasmodium parasites, which are transmitted by the bite of an infected mosquito. This enormous infection burden leads to some 660,000 lives lost to malaria each year, the majority of these young children in sub-Saharan Africa. While a vaccine to prevent malaria remains elusive, we depend on antimalarial compounds both to treat infections and prevent disease.

10 Jul 2013

ERYTECH reports fast take-off of GRASPA Phase IIb trial in patients with acute myeloid leukemia

ERYTECH, a French biopharmaceutical company that develops innovative treatments for acute leukemia and other oncology indications with unmet medical needs, announces a fast take-off of its Phase IIb study in Acute Myeloid Leukemia.

4 Jul 2013

CTI announces publication of preclinical, clinical data for pacritinib in Drugs of the Future 2013

Cell Therapeutics, Inc. today announced that a comprehensive article summarizing preclinical and clinical data for pacritinib, an oral JAK2/FLT3 inhibitor, authored by Srdan Verstovsek, M.D., Ph.D., et al., was published in the journal Drugs of the Future 2013.

3 Jul 2013

UCLA researchers introduce gene therapy technique to treat sickle cell disease

Researchers at UCLA's Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research have successfully established the foundation for using hematopoietic (blood-producing) stem cells from the bone marrow of patients with sickle cell disease to treat the disease.

2 Jul 2013

$Higher levels of Omega-3 fatty acids may reduce risk for hip fractures in postmenopausal women$

Higher levels of Omega-3 fatty acids may reduce risk for hip fractures in postmenopausal women

Higher levels of omega-3 fatty acids in the blood may reduce the risk for hip fractures in postmenopausal women, recent research suggests.

28 Jun 2013

Queen Mary engineers develop red blood cells simulator to help treat circulatory problems

Engineers from Queen Mary, University of London have developed the world's most precise computer simulation of how red blood cells might travel around the body to help doctors treat people with serious circulatory problems.

28 Jun 2013

Administering immunoglobulins to pregnant women may prevent Rh blood disorder in newborns

Swedish researchers determined that administering anti-D antibodies (immunoglobulins) to pregnant women who were Rhesus D (RhD) negative could prevent hemolytic disease in the infant.

27 Jun 2013

Researchers develop breakthrough approach to reduce harmful effects from blood transfusions

Researchers from Case Western Reserve University School of Medicine have developed an unprecedented approach to restore nitric oxide to donated blood, a breakthrough that could dramatically reduce harmful effects from transfusions.

26 Jun 2013

New study provides guidelines for stem cell transplantation in older MDS patients

A new study by an international team led by Dana-Farber Cancer Institute scientists provides the first statistically-based guidelines for determining whether a stem cell transplant is appropriate for older patients with myelodysplastic syndromes - the most common blood disorders in people over 60 years of age, and frequently a precursor for leukemia.

25 Jun 2013

Administering large iron doses over short period of time increases patients' risk of infections

While intravenous iron is critical for maintaining the health of many dialysis patients, administering large doses over a short period of time increases patients' risk of developing serious infections, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). Smaller doses given for a longer period of time appears to be much safer.

24 Jun 2013

European Commission amends marketing authorisation for Celgene's REVLIMID

Celgene International Sàrl was today notified that the European Commission has amended the marketing authorisation for REVLIMID. This decision means that REVLIMID is now approved to treat patients with transfusion-dependent anaemia due to low or intermediate-1 risk myelodysplastic syndromes associated with an isolated deletion 5q cytogenetic abnormality when other therapeutic options are insufficient or inadequate.

17 Jun 2013

New research reports that UnaG protein could lead to new liver test

Many scientists dream of making a single discovery that provides fundamental insight into nature, may be used to help save human lives, and can assist in the preservation of an endangered species. In new research reported in the journal Cell, a Japanese team is on the verge of accomplishing this nearly impossible feat.

17 Jun 2013

Researchers to launch Phase II clinical trial to investigate potential new therapy for sickle cell anemia

Seeking to improve the lives of sickle cell anemia sufferers around the world, researchers from the La Jolla Institute for Allergy and Immunology, the Dana-Farber/Children's Hospital Cancer Center in Boston and the BloodCenter of Wisconsin in Milwaukee and others are preparing to launch Phase II of a clinical trial to investigate a potential new therapy for reducing the disorder's severest symptoms.

12 Jun 2013

Red Blood Cells News and Research

CWRU grants technology transfer option to Disease Diagnostic Group to evaluate RAM device

CHOP researchers advance stem cell studies in childhood leukemia, Diamond Blackfan anemia

AstraZeneca, FibroGen partner to develop, commercialize anemia drug candidate FG-4592

Interferon-free treatment for genotype-1b hepatitis C patients: an interview with Professor Wulf Boecher, Boehringer Ingelheim

Rapamycin extends mice lifespan but has limited effects on aging

Fixed-ratio transfusion protocol in trauma patients is feasible, but wastes blood plasma

Nerves play critical role in development and spread of prostate tumors, say researchers

Researchers discover new class of antimalarial compounds

ERYTECH reports fast take-off of GRASPA Phase IIb trial in patients with acute myeloid leukemia

CTI announces publication of preclinical, clinical data for pacritinib in Drugs of the Future 2013

UCLA researchers introduce gene therapy technique to treat sickle cell disease

Higher levels of Omega-3 fatty acids may reduce risk for hip fractures in postmenopausal women

Queen Mary engineers develop red blood cells simulator to help treat circulatory problems

Administering immunoglobulins to pregnant women may prevent Rh blood disorder in newborns

Researchers develop breakthrough approach to reduce harmful effects from blood transfusions

New study provides guidelines for stem cell transplantation in older MDS patients

Administering large iron doses over short period of time increases patients' risk of infections

European Commission amends marketing authorisation for Celgene's REVLIMID

New research reports that UnaG protein could lead to new liver test

Researchers to launch Phase II clinical trial to investigate potential new therapy for sickle cell anemia

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