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Scientists create method for mapping genome-wide DNA damage caused by chemical carcinogen

Scientists have known for decades that smoking cigarettes causes DNA damage, which leads to lung cancer. Now, for the first time, UNC School of Medicine scientists created a method for effectively mapping that DNA damage at high resolution across the genome.

13 Jun 2017

Scientists identify microtubule-based therapy to alleviate Gulf War Illness symptoms

At least 100,000 military veterans who served in the 1990-1991 Gulf War were exposed to chemical weapons, released into the air after the United States bombed an ammunition depot in Khamisiyah, Iraq.

7 Jun 2017

Association found between the uptake of various elements during pregnancy and autism risk

According to a study published on June 1 in Nature Communications, differences in the uptake of multiple toxic and essential elements over the second and third trimesters and in the early postnatal periods of pregnancy are connected with the risk of developing autism spectrum disorders (ASDs).

2 Jun 2017

Differences in uptake of toxins, nutritional elements during late pregnancy and early life linked to ASD risk

Using evidence found in baby teeth, researchers from The Senator Frank R. Lautenberg Environmental Health Sciences Laboratory and The Seaver Autism Center for Research and Treatment at Mount Sinai found that differences in the uptake of multiple toxic and essential elements over the second and third trimesters and early postnatal periods are associated with the risk of developing autism spectrum disorders (ASD), according to a study published June 1 in the journal Nature Communications.

1 Jun 2017

WHO calls for action to stamp out tobacco use

According to a first-ever WHO report on tobacco, stamping out its use could save millions of people’s lives, reduce levels of poverty and decrease damage to the environment.

31 May 2017

JGU chemists develop technique that reduces toxic effects of cigarettes

Chemists at Johannes Gutenberg University Mainz have developed a technique that reduces the toxic effects of commercially available cigarettes.

30 May 2017

TSRI scientists discover potential new therapy to stop deadly botulinum neurotoxin

Botulinum neurotoxin is probably best known to Americans as BOTOX, a cosmetic medicine, rather than as a cause of potentially dangerous foodborne illnesses.

26 May 2017

Clinical study tests 100-year-old drug in children with autism spectrum disorder

In a small, randomized Phase I/II clinical trial (SAT1), researchers at University of California San Diego School of Medicine say a 100-year-old drug called suramin, originally developed to treat African sleeping sickness, was safely administered to children with autism spectrum disorder (ASD), who subsequently displayed measurable, but transient, improvement in core symptoms of autism.

26 May 2017

Study points to new pharmacologic approach to target chemo-resistant lung cancer

Patients with non-small cell lung cancer (NSCLC) often respond to standard chemotherapy, only to develop drug resistance later, and with fatal consequences.

23 May 2017

Light cigarettes have likely contributed to rise of lung adenocarcinoma, study shows

A new study shows that so-called "light" cigarettes have no health benefits to smokers and have likely contributed to the rise of a certain form of lung cancer that occurs deep in the lungs.

22 May 2017

New findings could lead to first broadly effective ebolavirus therapies and vaccines

After analyzing the blood of a survivor of the 2013-16 Ebola outbreak, a team of scientists from academia, industry and the government has discovered the first natural human antibodies that can neutralize and protect animals against all three major disease-causing ebolaviruses.

19 May 2017

New disposable sensor device can identify disease markers in breath

A small, thin square of an organic plastic that can detect disease markers in breath or toxins in a building's air could soon be the basis of portable, disposable sensor devices.

18 May 2017

Scientists identify gene linked to incurable bowel disorders

A key gene that helps to explain an underlying cause of incurable bowel disorders such as Crohn's disease has been identified by scientists.

17 May 2017

‘Disease in a dish’ model pinpoints how defects in blood-brain barrier can cause psychomotor disorder

Scientists for the first time have assembled a "disease in a dish" model that pinpoints how a defect in the blood-brain barrier can produce an incurable psychomotor disorder, Allan-Herndon-Dudley syndrome.

17 May 2017

Scientists use AHDS patients’ cells to recreate disease and mimic blood-brain barrier

The blood-brain barrier is biology's proverbial double-edged sword. An impermeable shield of endothelial cells that protects our brains from toxins and other threats that may lurk in circulating blood, the barrier can also exclude therapeutic drugs and, at times, essential biomolecules required for healthy brain development.

17 May 2017

Poor environmental quality is linked to increased cancer incidence, say researchers

A new study has demonstrated an association between cancer incidence and poor environmental quality across U.S. counties. In counties where exposure to harmful environmental factors is highest, cancer rates are also highest, particularly the rates of breast cancer and prostate cancer.

9 May 2017

Researchers discover new defense mechanism against bacteria during wound healing

Researchers in dermatology at Lund University in Sweden believe they have cracked the mystery of why we are able to quickly prevent an infection from spreading uncontrollably in the body during wounding. They believe this knowledge may be of clinical significance for developing new ways to counteract bacteria.

5 May 2017

Study reveals critical role of omega-3 fatty acids in preserving integrity of the blood-brain barrier

Already extolled for their health benefits as a food compound, omega-3 fatty acids now appear to also play a critical role in preserving the integrity of the blood-brain barrier, which protects the central nervous system from blood-borne bacteria, toxins and other pathogens, according to new research from Harvard Medical School.

5 May 2017

Scientists map genetic changes that help drive aggressive brain tumor

University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators have mapped genetic changes that help drive an aggressive tumor as it develops in the brain – helping to lay the foundation for targeted treatment of the disease.

3 May 2017

Antidepressant improves drug delivery across the blood-brain barrier, rat study shows

NIH rat study suggests amitriptyline temporarily inhibits the blood-brain barrier, allowing drugs to enter the brain.

27 Apr 2017

Toxins News and Research

Scientists create method for mapping genome-wide DNA damage caused by chemical carcinogen

Scientists identify microtubule-based therapy to alleviate Gulf War Illness symptoms

Association found between the uptake of various elements during pregnancy and autism risk

Differences in uptake of toxins, nutritional elements during late pregnancy and early life linked to ASD risk

WHO calls for action to stamp out tobacco use

JGU chemists develop technique that reduces toxic effects of cigarettes

TSRI scientists discover potential new therapy to stop deadly botulinum neurotoxin

Clinical study tests 100-year-old drug in children with autism spectrum disorder

Study points to new pharmacologic approach to target chemo-resistant lung cancer

Light cigarettes have likely contributed to rise of lung adenocarcinoma, study shows

New findings could lead to first broadly effective ebolavirus therapies and vaccines

New disposable sensor device can identify disease markers in breath

Scientists identify gene linked to incurable bowel disorders

‘Disease in a dish’ model pinpoints how defects in blood-brain barrier can cause psychomotor disorder

Scientists use AHDS patients’ cells to recreate disease and mimic blood-brain barrier

Poor environmental quality is linked to increased cancer incidence, say researchers

Researchers discover new defense mechanism against bacteria during wound healing

Study reveals critical role of omega-3 fatty acids in preserving integrity of the blood-brain barrier

Scientists map genetic changes that help drive aggressive brain tumor

Antidepressant improves drug delivery across the blood-brain barrier, rat study shows

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