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Simple TB screening and isoniazid can be effective for HIV patients at risk for TB

The number one killer of HIV patients in resource-limited areas, including parts of Africa and India, is tuberculosis (TB), underscoring the need for optimal treatments and effective strategies to address this deadly co-infection. But TB is harder to detect in HIV-infected patients and diagnostic test results take time, so many healthcare providers prescribe multi-drug TB treatments as a precaution.

20 Mar 2016

Innovative treatment may help prevent brain swelling, death in stroke patients

New research has provided more evidence that an innovative treatment strategy may help prevent brain swelling and death in stroke patients. J. Marc Simard, professor of neurosurgery at the University of Maryland School of Medicine, along with colleagues at Yale University and Massachusetts General Hospital, found that Cirara, an investigational drug, powerfully reduced brain swelling and death in patients who had suffered a type of large stroke called malignant infarction, which normally carries a high mortality rate.

19 Mar 2016

UCMR researchers discover compounds that can attenuate virulence of Listeria monocytogenes

Scientists at Umea Centre for Microbial Research have discovered chemical compounds which are able to attenuate the virulence of the bacterial human pathogen Listeria monocytogenes. Their findings are published today in the high impact journal Cell Chemical Biology.

19 Mar 2016

Manipulation of NAD could lead to potential therapy for acute kidney injury

Approximately one out of five hospitalized adults and one out of three hospitalized children worldwide experience acute kidney injury, the sudden loss of kidney function. Many different factors, including surgery, chemotherapy or shock, can lead to acute kidney injury, but exactly why the kidneys are so vulnerable to these and other stressors has not been well understood.

19 Mar 2016

Intervention programme significantly decreases preschool children's disruptive behaviour

Training parents online and over the telephone significantly decreased preschool children's disruptive behaviour, shows the new Strongest Families study from the Research Centre for Child Psychiatry at the University of Turku.

18 Mar 2016

Clinical study finds no added benefit of using four TB drugs to save people with advanced HIV/AIDS

In a report on the so-called REMEMBER (Reducing Early Mortality and Early Morbidity by Empiric Tuberculosis Treatment) study -- a 10-nation, randomized clinical trial of adult outpatients -- investigators concluded that there was no added benefit of using four drugs for TB over just using one drug, isoniazid, to save lives in people with advanced HIV/AIDS.

18 Mar 2016

Vascular events in CML may not be linked to TKI therapy

The increased risk of vascular events observed among elderly patients with chronic myeloid leukaemia, compared with patients without cancer, may not be driven by tyrosine kinase inhibitor therapy, US researchers suggest.

17 Mar 2016

Austerity measures increase mortality rates in elderly pensioners

Rising mortality rates among pensioners aged 85 and over are linked to reductions in spending on income support for poorer pensioners, suggests new research published today by the Journal of the Royal Society of Medicine.

17 Mar 2016

Stimulus-induced discharges in critically ill not linked to in-hospital death

Stimulus-induced rhythmic, periodic or ictal discharges in critically ill patients are not independently associated with in-hospital death, but are often associated with other electrographic abnormalities signalling poor outcomes, electroencephalography findings show.

17 Mar 2016

MUSC surgeon awarded $3.8 million grant to evaluate transplant drug

Seldom can one say $3.8 million is just the tip of the iceberg, but a newly awarded grant from Gilead Sciences, Inc. is just that. MUSC transplant surgeon Kenneth Chavin, M.D., Ph.D., says the true value of the multi-center drug trial is closer to $26 million, including $22 million in free drugs provided by the pharmaceutical company.

17 Mar 2016

Low levels of radiation exposure does not affect health, study finds

Researchers in Europe have reviewed cancer rates among people in parts of the world where natural background radiation is higher than average and found that incidence is not as high as one might guess. The findings, published in the International Journal of Low Radiation suggests that science ought to take a second look at studies that correlate low levels of radiation exposure with detrimental health effects

16 Mar 2016

Study: New SARS-like WIV1-CoV virus poised to infect humans

A SARS-like virus found in Chinese horseshoe bats may be poised to infect humans without the need for adaptation, overcoming an initial barrier that could potentially set the stage for an outbreak according to a study at the University of North Carolina at Chapel Hill.

16 Mar 2016

Researchers exploring ways to prevent radiation-induced cancer risk in astronauts

NASA limits an astronaut's radiation exposures to doses that keep their added risk of fatal cancer below 3 percent. Unfortunately, that ceiling restricts the time an astronaut may spend in space, which in turn restricts the ability to perform longer missions, say a mission to Mars.

14 Mar 2016

Screening colonoscopy program brings down colorectal cancer rates in Germany

The introduction of screening colonoscopy in Germany is showing results: Within ten years of the start of this screening program for the early detection of colorectal cancer, the number of new cases has significantly dropped in the age groups 55 years and over.

14 Mar 2016

Breast cancer can be more aggressive in obese people

An international team of researchers, with the participation of the University of Granada, has revealed new data on why breast cancer has a higher incidence and is more aggressive in obese people. The reason is that peritumoral fat (the fat around the tumor) facilitates the expansion and invasion of cancer stem cells (CSCs), which are responsible of the onset and growth of the tumor.

11 Mar 2016

Low cost, easy-to-use test could help reduce TB death rate of HIV patients in sub-Saharan Africa

A low cost, easy to use, urine test to diagnose tuberculosis (TB) among patients with HIV could help reduce the TB death rate of HIV-positive patients in hospital, according to a new study published in The Lancet today.

10 Mar 2016

Use of radiotherapy focused around tumour bed with IMRT benefits breast cancer patients

Radiotherapy to the whole breast is standard treatment after breast-conserving surgery for women with early breast cancer, even those who have a low risk of the disease returning in the breast (local relapse). However, whole breast radiotherapy can cause changes in the appearance of the breast, which may also be firmer and tender to the touch, resulting in psychological distress.

10 Mar 2016

Clinician communication increases patient knowledge, relieves distress related to incidental nodule detection

A cross-sectional survey showed a quarter of patients with detected incidental pulmonary nodules experienced significant distress related to the nodule. Detailed clinician communication increased patient knowledge, relieved distress, and improved patient experience.

8 Mar 2016

Study finds strong link between postpartum disorder and suicide risk in new mothers

Over a period spanning four decades, a total of eight Danish women committed suicide within a year of being diagnosed with a birth-related psychiatric disorder, including severe episodes of postpartum depression or psychosis.

7 Mar 2016

Systemic sclerosis: an interview with Dr Kristin Highland

Systemic sclerosis, also known as scleroderma, is a rare disease characterized by the thickening and scarring of connective tissue of multiple organs in the body

7 Mar 2016

Mortality News and Research

Simple TB screening and isoniazid can be effective for HIV patients at risk for TB

Innovative treatment may help prevent brain swelling, death in stroke patients

UCMR researchers discover compounds that can attenuate virulence of Listeria monocytogenes

Manipulation of NAD could lead to potential therapy for acute kidney injury

Intervention programme significantly decreases preschool children's disruptive behaviour

Clinical study finds no added benefit of using four TB drugs to save people with advanced HIV/AIDS

Vascular events in CML may not be linked to TKI therapy

Austerity measures increase mortality rates in elderly pensioners

Stimulus-induced discharges in critically ill not linked to in-hospital death

MUSC surgeon awarded $3.8 million grant to evaluate transplant drug

Low levels of radiation exposure does not affect health, study finds

Study: New SARS-like WIV1-CoV virus poised to infect humans

Researchers exploring ways to prevent radiation-induced cancer risk in astronauts

Screening colonoscopy program brings down colorectal cancer rates in Germany

Breast cancer can be more aggressive in obese people

Low cost, easy-to-use test could help reduce TB death rate of HIV patients in sub-Saharan Africa

Use of radiotherapy focused around tumour bed with IMRT benefits breast cancer patients

Clinician communication increases patient knowledge, relieves distress related to incidental nodule detection

Study finds strong link between postpartum disorder and suicide risk in new mothers

Systemic sclerosis: an interview with Dr Kristin Highland

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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