Laboratory News and Research

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UMSOM researchers to test the safety, tolerability of prototype Shigella-ETEC vaccine

Each year, millions of people contract serious diarrheal illnesses typically from contaminated food and water. Among the biggest causes of diarrheal diseases are the bacteria Shigella and enterotoxigenic Escherichia coli, and researchers at the University of Maryland School of Medicine are testing a vaccine designed to offer protection against these serious pathogens.

10 Dec 2019

Tulane study focuses on treatment of preeclampsia

A Tulane University researcher has received a grant that will support the development of new imaging methods to improve the treatment of preeclampsia.

10 Dec 2019

New joint venture aims to develop implantable cell therapies for debilitating conditions with no cure

Mayo Clinic and W. L. Gore & Associates Inc., a global materials science company, have formed a joint venture to advance the development of implantable cell therapies to treat debilitating conditions with no cure. Avobis Bio will combine Mayo Clinic's clinical and cell expertise and Gore's expertise in material sciences to address some of the most challenging medical issues.

10 Dec 2019

Justified and unjustified violence in movies activate different parts of adolescent brain

The gun violence seen in popular PG-13 movies aimed at children and teenagers has more than doubled since the rating was introduced in 1984. The increasing on-screen gun violence has raised concerns that it will encourage imitation, especially when it is portrayed as "justified."

10 Dec 2019

Modifier gene offers a likely explanation for less infection in some patients with cystic fibrosis

Cystic fibrosis is caused by an inherited mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

10 Dec 2019

Study provides most detailed classification of acute myeloid leukemia, myelodysplastic syndrome

Results from a study conducted by St. Jude Children's Research Hospital and the Munich Leukemia Laboratory were presented today as a late-breaking abstract at the American Society of Hematology annual meeting. The study integrates genomic and transcriptomic sequencing to provide the most detailed classification of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) to date.

10 Dec 2019

Combination regimen shows promising results in preclinical models of triple negative breast cancer

Tumor volume in a preclinical model of triple negative breast cancer (TNBC) was reduced four times more when an experimental polo-like kinase 1 (PLK1) inhibitor was combined with a standard-of-care chemotherapeutic agent than when the agent was used alone.

10 Dec 2019

ERC promotes CRISPR research to better treat infections

Chase Beisel heads the "Synthetic Biology of RNA" research group at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg, a branch of the Helmholtz Centre for Infection Research in Braunschweig and run in collaboration with the Julius-Maximilians-Universität in Würzburg.

10 Dec 2019

UA physician-scientist to study how common stressors affect the aging process

The human body gets stressed every single day. Whether we contract a minor infection or even argue with a loved one, these small stressors impact our immune system.

10 Dec 2019

Neurons in the brain's motor cortex light up during speech of words and syllables

Neurons in the brain's motor cortex previously thought of as active mainly during hand and arm movements also light up during speech in a way that is similar to patterns of brain activity linked to these movements, suggest new findings published today in eLife.

10 Dec 2019

Risk of specific genetic translocation is higher in patients of African ancestry, shows study

Multiple myeloma is a plasma cell cancer that is more common in patients of African American descent than of European American descent.

10 Dec 2019

Mapping genetic links between diseases using data from electronic health records

Physicians use standard disease classifications based on symptoms or location in the body to help make diagnoses. These classifications, called nosologies, can help doctors understand which diseases are closely related, and thus may be caused by the same underlying issues or respond to the same treatments.

9 Dec 2019

Lactobacillus balances intestinal microbiome and ameliorates chronic alcohol-induced liver injury

Researchers demonstrated that Lactobacillus rhamnosus can dose-dependently reestablish a balanced intestinal microbiome and counter the liver-damaging effects of alcohol consumption in mice to reverse the results of chronic alcohol-induced liver injury.

9 Dec 2019

New method to create artificial cells that are active and mimic living cells

Protocells - artificial cells - that are active and mimic living cells by moving independently and that are biocompatible and enzymatically active are now possible using an improved method developed by Penn State researchers.

9 Dec 2019

Groundbreaking technique could help predict a protein's interactions with other proteins

Proteins are the building blocks of life and play a key role in all biological processes. Understanding how they interact with their environment is therefore vital to developing effective therapeutics and the foundation for designing artificial cells.

9 Dec 2019

Research shows how high levels of blood fat induce inflammation and organ damage

Viral and bacterial infections are not the only causes of inflammation of body tissue. It has been known for some time that certain fat molecules in our bloodstream can also trigger an inflammatory response.

9 Dec 2019

Scientists develop a method of targeted drug delivery to cancer cells

A team of scientists from Peter the Great St.Petersburg Polytechnic University together with their colleagues developed a method of targeted drug delivery to cancer cells. The discovery is based on the use of mesenchymal stem cells and microcapsules made of polymeric compounds.

9 Dec 2019

Laboratory News and Research

UMSOM researchers to test the safety, tolerability of prototype Shigella-ETEC vaccine

Tulane study focuses on treatment of preeclampsia

New joint venture aims to develop implantable cell therapies for debilitating conditions with no cure

Justified and unjustified violence in movies activate different parts of adolescent brain

Modifier gene offers a likely explanation for less infection in some patients with cystic fibrosis

Study provides most detailed classification of acute myeloid leukemia, myelodysplastic syndrome

Combination regimen shows promising results in preclinical models of triple negative breast cancer

ERC promotes CRISPR research to better treat infections

UA physician-scientist to study how common stressors affect the aging process

Neurons in the brain's motor cortex light up during speech of words and syllables

Risk of specific genetic translocation is higher in patients of African ancestry, shows study

Mapping genetic links between diseases using data from electronic health records

Lactobacillus balances intestinal microbiome and ameliorates chronic alcohol-induced liver injury

New method to create artificial cells that are active and mimic living cells

Groundbreaking technique could help predict a protein's interactions with other proteins

Research shows how high levels of blood fat induce inflammation and organ damage

Scientists develop a method of targeted drug delivery to cancer cells

Important biomarker may help in determining prognosis of brain cancer patients

Malaysia announces first case of polio in the country for 27 years

Thermo Fisher Scientific to accelerate genomic profiling process in hematology and oncology labs

Pittcon 2024 - Advancing Science on the West Coast eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics